Anti-CRISPR-Based and CRISPR-Based Genome Editing of Sulfolobus islandicus Rod-Shaped Virus 2

Autor: David Mayo-Muñoz, Fei He, Jacob Bruun Jørgensen, Poul Kári Madsen, Yuvaraj Bhoobalan-Chitty, Xu Peng

Publikováno v: Viruses, Vol 10, Iss 12, p 695 (2018)

Genetic engineering of viruses has generally been challenging. This is also true for archaeal rod-shaped viruses, which carry linear double-stranded DNA genomes with hairpin ends. In this paper, we describe two different genome editing approaches to

Externí odkaz: https://doaj.org/article/d4847d84960e4aa19c69adf3700e64a0

Type IV CRISPR–Cas systems are highly diverse and involved in competition between plasmids

Autor: Jakob Russel, Rafael Pinilla-Redondo, Lennart Randau, Shiraz A. Shah, S. J. Soerensen, Roger A. Garrett, David Mayo-Muñoz

Publikováno v: Nucleic Acids Research
Pinilla-Redondo, R, Mayo-Muñoz, D, Russel, J, Garrett, R A, Randau, L, Sørensen, S J & Shah, S A 2020, ' Type IV CRISPR-Cas systems are highly diverse and involved in competition between plasmids ', Nucleic Acids Research, vol. 48, no. 4, pp. 2000-2012 . https://doi.org/10.1093/nar/gkz1197

CRISPR-Cas systems provide prokaryotes with adaptive immune functions against viruses and other genetic parasites by leveraging small non-coding RNAs for nuclease-dependent degradation of their nucleic acid targets. In contrast to all other types of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b029ad0978d7b42d5968c52e279435c3
https://doi.org/10.1093/nar/gkz1197

CRISPRCasTyper: Automated Identification, Annotation, and Classification of CRISPR-Cas Loci

Autor: Rafael Pinilla-Redondo, Søren J. Sørensen, Jakob Russel, David Mayo-Muñoz, Shiraz A. Shah

Publikováno v: The CRISPR journal. 3(6)

Automated classification of CRISPR-Cas systems has been challenged by their dynamic nature and expanding classification. Here, we developed CRISPRCasTyper, an automated tool with improved capabilities for identifying and typing CRISPR arrays and cas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb25cd7dfec023f705d2f62a0d1e0f2
https://pubmed.ncbi.nlm.nih.gov/33275853

Viral Genome Isolation from Human Faeces for Succession Assessment of the Human Gut Virome

Autor: David, Mayo-Muñoz

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1838

Despite the important role of the microbiota in the human gastrointestinal tract (GIT) and its impact on life-long health, the successional process through which this microbial community develops during infancy is still poorly understood. Specially,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2101b9f5688681ce783bc4632d7d907
https://pubmed.ncbi.nlm.nih.gov/30128992

Anti-CRISPR-Based and CRISPR-Based Genome Editing of Sulfolobus islandicus Rod-Shaped Virus 2

Autor: Fei He, Jacob Bruun Jørgensen, Yuvaraj Bhoobalan-Chitty, Poul Kári Madsen, David Mayo-Muñoz, Xu Peng

Publikováno v: Mayo-Muñoz, D, He, F, Jørgensen, J B, Madsen, P K, Bhoobalan-Chitty, Y & Peng, X 2018, ' Anti-CRISPR-Based and CRISPR-Based Genome Editing of Sulfolobus islandicus Rod-Shaped Virus 2 ', Viruses, vol. 10, no. 12, 695, pp. 1-17 . https://doi.org/10.3390/v10120695
Viruses
Volume 10
Issue 12
Viruses, Vol 10, Iss 12, p 695 (2018)

Genetic engineering of viruses has generally been challenging. This is also true for archaeal rod-shaped viruses, which carry linear double-stranded DNA genomes with hairpin ends. In this paper, we describe two different genome editing approaches to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b26d80dc348f558bea460c99be720f
https://curis.ku.dk/portal/da/publications/anticrisprbased-and-crisprbased-genome-editing-of-sulfolobus-islandicus-rodshaped-virus-2(85cd8e05-a21d-4dc2-9b8d-b1049762fae7).html