Zobrazeno 1 - 10
of 20
pro vyhledávání: '"David Mauduit"'
Autor:
Isabel Punzón, David Mauduit, Bryan Holvoet, Jean-Laurent Thibaud, Pauline de Fornel, Christophe M. Deroose, Nicolas Blanchard-Gutton, Jean-Thomas Vilquin, Maurilio Sampaolesi, Inès Barthélémy, Stéphane Blot
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 317-327 (2020)
Stem cell-based therapies are a promising approach for the treatment of degenerative muscular diseases; however, clinical trials have shown inconclusive and even disappointing results so far. Noninvasive cell monitoring by medicine imaging could impr
Externí odkaz:
https://doaj.org/article/e8ffdcf12e3d4aac926b9e51736f109b
Autor:
David Mauduit, Ibrahim Ihsan Taskiran, Liesbeth Minnoye, Maxime de Waegeneer, Valerie Christiaens, Gert Hulselmans, Jonas Demeulemeester, Jasper Wouters, Stein Aerts
Publikováno v:
eLife, Vol 10 (2021)
Understanding how enhancers drive cell-type specificity and efficiently identifying them is essential for the development of innovative therapeutic strategies. In melanoma, the melanocytic (MEL) and the mesenchymal-like (MES) states present themselve
Externí odkaz:
https://doaj.org/article/8cc6826acf8940b387a34efa788b6d00
Autor:
Carmen Bravo González‐Blas, Xiao‐Jiang Quan, Ramon Duran‐Romaña, Ibrahim Ihsan Taskiran, Duygu Koldere, Kristofer Davie, Valerie Christiaens, Samira Makhzami, Gert Hulselmans, Maxime deWaegeneer, David Mauduit, Suresh Poovathingal, Sara Aibar, Stein Aerts
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 5, Pp n/a-n/a (2020)
Abstract Single‐cell technologies allow measuring chromatin accessibility and gene expression in each cell, but jointly utilizing both layers to map bona fide gene regulatory networks and enhancers remains challenging. Here, we generate independent
Externí odkaz:
https://doaj.org/article/32070ef12bcb4df19d0631375f7ed3e5
Autor:
Carmen Bravo González-Blas, Irina Matetovici, Hanne Hillen, Ibrahim Ihsan Taskiran, Roel Vandepoel, Valerie Christiaens, Leticia Sansores-García, Elisabeth Verboven, Gert Hulselmans, Suresh Poovathingal, Jonas Demeulemeester, Nikoleta Psatha, David Mauduit, Georg Halder, Stein Aerts
Cell type identity is encoded by gene regulatory networks (GRN), in which transcription factors (TFs) bind to enhancers to regulate target gene expression. In the mammalian liver, lineage TFs have been characterized for the main cell types, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95e9f9ff0c29adecbe4774fcbe8d6a24
https://doi.org/10.1101/2022.12.08.519575
https://doi.org/10.1101/2022.12.08.519575
Autor:
David Mauduit, Maxime de Waegeneer, Florian Rambow, Dennis Pedri, Jean-Christophe Marine, Samira Makhzami, Carmen Bravo González-Blas, Zeynep Kalender-Atak, Kristofer Davie, Stein Aerts, Ghanem Elias Ghanem, Ahmad Najem, Suresh Poovathingal, Michael Dewaele, Valerie Christiaens, Liesbeth Minnoye, Jasper Wouters, Gert Hulselmans, Frederik Ceyssens, Katina I. Spanier
Publikováno v:
Nature Cell Biology
Melanoma cells can switch between a melanocytic and a mesenchymal-like state. Scattered evidence indicates that additional intermediate state(s) may exist. Here, to search for such states and decipher their underlying gene regulatory network (GRN), w
Autor:
David Mauduit, Stéphane Blot, Nicolas Blanchard-Gutton, Isabel Punzón, Maurilio Sampaolesi, Bryan Holvoet, Inès Barthélémy, Christophe Deroose, Jean-Thomas Vilquin, Jean-Laurent Thibaud, Pauline de Fornel
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods and Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2020, 17, pp.317-327. ⟨10.1016/j.omtm.2019.12.011⟩
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 317-327 (2020)
Molecular Therapy-Methods and Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2020, 17, pp.317-327. ⟨10.1016/j.omtm.2019.12.011⟩
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 317-327 (2020)
Stem cell-based therapies are a promising approach for the treatment of degenerative muscular diseases; however, clinical trials have shown inconclusive and even disappointing results so far. Noninvasive cell monitoring by medicine imaging could impr
Autor:
David Mauduit, Ibrahim Ihsan Taskiran, Liesbeth Minnoye, Maxime de Waegeneer, Valerie Christiaens, Gert Hulselmans, Jonas Demeulemeester, Jasper Wouters, Stein Aerts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d8f9ec62bcd4e4bd311c0d8ca79b0d
https://doi.org/10.7554/elife.71735.sa2
https://doi.org/10.7554/elife.71735.sa2
Autor:
Valerie Christiaens, Liesbeth Minnoye, Ibrahim Ihsan Taskiran, Stein Aerts, Jens Wouters, Gert Hulselmans, M. De Waegeneer, David Mauduit, Jonas Demeulemeester
Understanding how enhancers drive cell type specificity and efficiently identifying them is essential for the development of innovative therapeutic strategies. In melanoma, the melanocytic (MEL) and the mesenchymal-like (MES) states present themselve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94962a247da34ca853e8e4bc829974f4
https://doi.org/10.1101/2021.07.27.453936
https://doi.org/10.1101/2021.07.27.453936
Autor:
Zeynep Kalender Atak, Jonas Demeulemeester, Ibrahim Ihsan Taskiran, Stein Aerts, Christopher Flerin, Valerie Christiaens, Jasper Wouters, Gert Hulselmans, Ghanem Elias Ghanem, Liesbeth Minnoye, David Mauduit
Publikováno v:
Genome research, 31 (6
Genome Res
Genome Research
Genome Res
Genome Research
Genomic sequence variation within enhancers and promoters can have a significant impact on the cellular state and phenotype. However, sifting through the millions of candidate variants in a personal genome or a cancer genome, to identify those that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d68150a28d624b0c14940612ffdda8
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326913
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/326913
Autor:
Abraham, Avrah, Adjoumane, Marcellin Manzan André, Ali, Atif, van den Bergh, Justine, David-Mauduit, Pacôme, Das, Ashmita, Dinh, Hong Huy, van der Doorn, Laura, Gegout, Layla, Ha, Hoang Hieu, Ha, Ngoc Hai Binh, Heer, Marieke, Hillesheim, Alexandra, Huertas Garcia, Marina, Jacoby, Emma, Jumbeck, Angela Lorene, Malhotra, Chaandi, Parihar, Pratik Vijay, Proud, Mary Mackenzie, Ngo, Thi Ngoc Thuy, Nguyen, Tuan Viet, Nieuw, Christle, Oksiutycz-Munyawiri, Anetta, Pham, Quang Khai, Proctor, Jess, Romijn, Gijs, Slob, Wietse, Soriano, Paloma, Suarez Escalante, Myrka, Tran, Minh Man, Tran, The Kiet, Velema, Pia Lou, Sonnenfeld, D., Thanh Hien Ho, Thi, Ross, V.M., Student, J.R.
Many innovations have been developed as a response to the challenges of COVID-19 to make cities more green, resilient and inclusive. In these complex urban systems, solutions must be made taking into consideration how they affect the wider context. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::097e0811ac07a358f4041a3a990dbd7c
https://research.wur.nl/en/publications/resilience-beyond-covid-19-piecing-together-the-puzzle-of-green-a
https://research.wur.nl/en/publications/resilience-beyond-covid-19-piecing-together-the-puzzle-of-green-a