Zobrazeno 1 - 10
of 24
pro vyhledávání: '"David Mathar"'
Autor:
Karima Chakroun, Antonius Wiehler, Ben Wagner, David Mathar, Florian Ganzer, Thilo van Eimeren, Tobias Sommer, Jan Peters
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Dopamine fundamentally contributes to reinforcement learning, but recent accounts also suggest a contribution to specific action selection mechanisms and the regulation of response vigour. Here, we examine dopaminergic mechanisms underlying
Externí odkaz:
https://doaj.org/article/6fb6176da3044439b1fa6b57fcb8cae7
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 12, p e1010785 (2022)
Supplementation with the catecholamine precursor L-Tyrosine might enhance cognitive performance, but overall findings are mixed. Here, we investigate the effect of a single dose of tyrosine (2g) vs. placebo on two catecholamine-dependent trans-diagno
Externí odkaz:
https://doaj.org/article/fcd1b8a67f924b258f9d49b0d80a9eaf
Publikováno v:
Computational Psychiatry, Vol 6, Iss 1 (2022)
Gambling disorder is a behavioral addiction that negatively impacts personal finances, work, relationships and mental health. In this pre-registered study (https://osf.io/5ptz9/) we investigated the impact of real-life gambling environments on two co
Externí odkaz:
https://doaj.org/article/8ce1e18e542d4024bf672f0c2e740643
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008410 (2020)
Computational modeling of dopamine transmission is challenged by complex underlying mechanisms. Here we present a new computational model that (I) simultaneously regards release, diffusion and uptake of dopamine, (II) considers multiple terminal rele
Externí odkaz:
https://doaj.org/article/e7b693942ccd4c2388ee4ad3e2ca9ec4
Publikováno v:
eLife, Vol 9 (2020)
Involvement of dopamine in regulating exploration during decision-making has long been hypothesized, but direct causal evidence in humans is still lacking. Here, we use a combination of computational modeling, pharmacological intervention and functio
Externí odkaz:
https://doaj.org/article/11a498eee8dd4ea8a71160de62ab424e
Publikováno v:
Computational Psychiatry. 6:142-165
Gambling disorder is a behavioral addiction that negatively impacts personal finances, work, relationships and mental health. In this pre-registered study (https://osf.io/5ptz9/?view_only=62956a2afcd1495984db4be18c54b50a) we investigated the impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718778ac22847d84ca81cca68d727a37
https://doi.org/10.5334/cpsy.84
https://doi.org/10.5334/cpsy.84
When given a choice, humans and many animals prefer smaller but sooner over larger but later rewards, a tendency referred to as temporal discounting. Alterations in devaluation of future rewards have been reported in a range of maladaptive behaviors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5b8611096f733b007999a65ae47a86
https://doi.org/10.1101/2022.11.21.517327
https://doi.org/10.1101/2022.11.21.517327
Autor:
Karima Chakroun, Antonius Wiehler, Ben Wagner, David Mathar, Florian Ganzer, Thilo vanEimeren, Tobias Sommer, Jan Peters
Dopamine fundamentally contributes to reinforcement learning by encoding prediction errors, deviations of an outcome from expectation. Prediction error coding in dopaminergic regions in human functional neuroimaging studies is well replicated. In con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d72ed12cd97810b918e4ca72fba99512
https://doi.org/10.1101/2022.09.29.509499
https://doi.org/10.1101/2022.09.29.509499
Computational psychiatry focuses on identifying core cognitive processes that appear altered across a broad range of psychiatric disorders. Temporal discounting of future rewards and model-based control during reinforcement learning have proven as tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39be820a93cc19c246b78ea8f3377f43
https://doi.org/10.1101/2022.09.04.506507
https://doi.org/10.1101/2022.09.04.506507
Supplementation with the catecholamine precursor L-Tyrosine might enhance cognitive performance, but overall findings are mixed. Here, we investigate the effect of a single dose of tyrosine (2g) vs. placebo on two key aspects of catecholamine-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ed951b734880f54f246512b4617d47e
https://doi.org/10.1101/2022.02.09.479693
https://doi.org/10.1101/2022.02.09.479693