Zobrazeno 1 - 10
of 27
pro vyhledávání: '"David M. Woodcock"'
Autor:
Rebecca Randell, Lynn McVey, Judy Wright, Hadar Zaman, V-Lin Cheong, David M Woodcock, Frances Healey, Dawn Dowding, Peter Gardner, Nicholas R Hardiker, Alison Lynch, Chris Todd, Christopher Davey, Natasha Alvarado
Publikováno v:
Health and Social Care Delivery Research, Vol 12, Iss 05 (2024)
Background Falls are the most common safety incident reported by acute hospitals. The National Institute of Health and Care Excellence recommends multifactorial falls risk assessment and tailored interventions, but implementation is variable. Aim To
Externí odkaz:
https://doaj.org/article/6dbac2aa25a64b5ab661325472e995a5
Publikováno v:
Gene. 206:63-67
Mouse ES cells with a null mutation of the known DNA methyltransferase retain some residual DNA methylation and can methylate foreign sequences de novo. We have used bisulfite genomic sequencing to examine the sequence specificity and distributions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c949b672b1f2a556c67576982c9640fd
https://doi.org/10.1016/s0378-1119(97)00566-0
https://doi.org/10.1016/s0378-1119(97)00566-0
Publikováno v:
Journal of Oncology Pharmacy Practice. 3:186-192
Objective. To provide an overview of the known pharmacological activity of the solvent for pacli taxel, Cremophor, and the implications for therapy with paclitaxel. Data Sources. Following an outline of the chemistry of Cremophor and its potential to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::553dfa35b5dd87fd858519a7972d7e73
https://doi.org/10.1177/107815529700300402
https://doi.org/10.1177/107815529700300402
Autor:
Michael Millward, Carmel G. Morton, Martha E. Linsenmeyer, Lorraine K. Webster, James F. Bishop, David M. Woodcock
Publikováno v:
JNCI: Journal of the National Cancer Institute. 85:1685-1690
Background Paclitaxel (Taxol) is the first of a new class of cytotoxic agents with activity against tumors resistant to other drugs. For clinical use, paclitaxel is currently formulated in a vehicle of 50% ethanol and 50% polyethoxylated surfactant C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf1894ef70be83ec306aa1148e86cce
https://doi.org/10.1093/jnci/85.20.1685
https://doi.org/10.1093/jnci/85.20.1685
Publikováno v:
Gene. 124:37-44
We have tested whether, and to what extent, recombinant clones from DNA segments with 5-methylation of cytosines recovered in methylation-restrictive (mcr+) hosts contain mutations. We constructed a model system in which the tetracycline-resistance-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cc6ba79362525112ef3a3ec9e3c0ac
https://doi.org/10.1016/0378-1119(93)90759-v
https://doi.org/10.1016/0378-1119(93)90759-v
Publikováno v:
Gene. 124:29-35
We have attempted to produce Escherichia coli strains with the optimal combination of host mutations required for the construction of genomic libraries in lambda and cosmid vectors. For lambda vectors, we defined this as a strain that combined high e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6505e825258cd9d7aaaa728b2535d3
https://doi.org/10.1016/0378-1119(93)90758-u
https://doi.org/10.1016/0378-1119(93)90758-u
Autor:
J.P. Doherty, Penelope J. Crowther, Martha E. Linsenmeyer, M.W. Graham, Michael Williamson, David M. Woodcock
Publikováno v:
Gene. 98:77-82
The use of optimally methylation-tolerant mcrA − mcrB − strains has been shown to produce an over tenfold increase in the plating efficiencies of mammalian genomic libraries, compared to a superior conventional phage host strain LE392 which is mc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497be21b326bd08f99694af20d758abd
https://doi.org/10.1016/0378-1119(91)90106-l
https://doi.org/10.1016/0378-1119(91)90106-l
Publikováno v:
Plant Molecular Biology Reporter. 8:18-27
It has recently become apparent that many strains ofE. coli contain nucleases encoded by themcrA andmcrB loci that, recognize the modified base 5-methylcytosine in DNA. Plant DNAs have particularly high levels of this modification and the activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39c9b4f7b15490189fe900a96ca35ae3
https://doi.org/10.1007/bf02668877
https://doi.org/10.1007/bf02668877
Publikováno v:
SPIE Proceedings.
We use finite-element simulations of a micromachined gas-flow sensor as an example to demonstrate and critically compare various design- and analysis-of-experiments methods for the generation of simple, surrogate functional approximations. Such appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd9fe395d7aa3697346ae99246d59943
https://doi.org/10.1117/12.360486
https://doi.org/10.1117/12.360486
Autor:
Celine B. Lawler, Martha E. Linsenmeyer, David M. Woodcock, William D. Warren, Judith P. Doherty
Publikováno v:
The Journal of biological chemistry. 272(12)
We have investigated the function and sequence specificity of DNA methylation in the hypermethylated CpG island promoter region of the endogenous human LINE-1 (L1) retrotransposon family. In nontransformed human embryonic fibroblasts, inhibition of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86644121beeded23746a8cea1d9db30
https://pubmed.ncbi.nlm.nih.gov/9065445
https://pubmed.ncbi.nlm.nih.gov/9065445