Výsledky vyhledávání - "David M. Stout"

Akademický článek

Advanced artificial intelligence–guided hemodynamic management within cardiac enhanced recovery after surgery pathways: A multi-institution reviewCentral MessagePerspective

Autor: V. Seenu Reddy, MD, MBA, FACS, FACC, David M. Stout, MD, Robert Fletcher, MS, Andrew Barksdale, MD, FACS, Manesh Parikshak, MD, FACS, Chanice Johns, RN, BSN, CCRN, Marc Gerdisch, MD, FACS, FACC, FHRS

Publikováno v: JTCVS Open, Vol 16, Iss , Pp 480-489 (2023)

Objective: The study objective was to report early outcomes of integrating Hypotension Prediction Index–guided hemodynamic management within a cardiac enhanced recovery pathway on total initial ventilation hours and length of stay in the intensive

Externí odkaz: https://doaj.org/article/20b4dd604317462b8be3af4d5219e4d0

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Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists

Autor: YiLi Ding, Yongxin Han, François G. Gervais, Shilan Liu, Leanne Bedard, Robert B. Lobell, Hongmei Wang, Shuhui Chen, Angela Wong, Martin Henault, Jingchao Dong, David M. Stout, Hao Wu, Ge Li, Stacia Kargman, Nicole Sawyer, R. W. Friesen, Yinhui Liu, Manuel Chan

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 19:5741-5745

We describe herein a novel series of 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective inhibitors against the CXCR2 chemokine receptor and IL-8-mediated chemotaxis of a CXCR2-expressing cell line. Furthermore, these alkyl-hydrazin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffc3d9548b1256ab1668d8e9a829d4a
https://doi.org/10.1016/j.bmcl.2009.08.014

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Bee Associates of Flowering Astragalus and Onobrychis Genebank Accessions at a Snake River Site in Eastern Washington

Autor: Richard W. Rust, Stephen L. Clement, Terry L. Griswold, Barbara C. Hellier, David M. Stout

Publikováno v: Ca

A 3 yr survey of the bee associates of flowering accessions of Astragalus and Onobrychis species was conducted in open-pollinated field nurseries at Central Ferry, Washington to gain insight into the potential for bee-mediated inter-accession out-cro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc1b9f5944e5dd4d2b5435bd51225e3
https://doi.org/10.2317/0505.02.1

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MarketLine Company Profile: Jabil Inc.

Publikováno v: Jabil Inc. MarketLine Company Profile. 10/8/2024, p1-32. 32p.

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Identification and structure-activity relationship studies of 3-methylene-2-norbornanone as potent anti-proliferative agents presumably working through p53 mediated apoptosis

Autor: David M. Stout, Long Ye, Prabhavathi B. Fernandes, Jeanette Hill, N. Laxma Reddy

Publikováno v: Bioorganicmedicinal chemistry letters. 14(22)

We have identified a novel series of α-methylene carbonyl compounds through structure–activity relationship (SAR) studies with high levels of anti-proliferative activities. The lead molecule, 3-methylene-2-norbornanone ( 3 ) showed potent activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce6037d2033d471cf97c571a077d056
https://pubmed.ncbi.nlm.nih.gov/15482940

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Asymmetric Strecker synthesis: isolation of pure enantiomers and mechanistic implications

Autor: Lawrence A. Black, David M. Stout, William L. Matier

Publikováno v: The Journal of Organic Chemistry. 48:5369-5373

Etude du mecanisme de la reaction de Strecker conduisant a des α-[phenyl-1 ethylamino] benzeneacetonitriles par reaction de derives du benzaldehyde avec NaCN et la phenyl-1 ethylamine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93f4cdb8cf5f68e97ffcf25dadeb749b
https://doi.org/10.1021/jo00174a046

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Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 2. Amides

Autor: William L. Matier, Barry S. Brown, Robert D. Reynolds, David M. Stout, Cynthia Barcelon-Yang

Publikováno v: Journal of Medicinal Chemistry. 27:1347-1350

Thirty amides patterned after the antiarrhythmic drug changrolin were synthesized and their antiarrhythmic and parasympatholytic activities were assessed. There was no correlation between antiarrhythmic and parasympatholytic activities. Several of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93754f251edd542c7a0bfa210aa09ca2
https://doi.org/10.1021/jm00376a022

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Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 3. Modifications to the linkage region (region 3)

Autor: W. L. Matier, Cynthia Barcelon-Yang, David M. Stout, Barry S. Brown, Robert D. Reynolds

Publikováno v: Journal of Medicinal Chemistry. 28:295-298

As part of a continuing program of systematically modifying the structure of the class I antiarrhythmic drug changrolin, we synthesized 15 analogues in which the linkage between the two aromatic regions was altered. High antiarrhythmic activity and l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fad73c1ee6f6dddf0d93040c93e5158
https://doi.org/10.1021/jm00381a006

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