Zobrazeno 1 - 10 of 45 pro vyhledávání: '"David M. Small"'
1
Akademický článek
An intravital window to image the colon in real time
Autor: Nikolai Rakhilin, Aliesha Garrett, Chi-Yong Eom, Katherine Ramos Chavez, David M. Small, Andrea R. Daniel, Melanie M. Kaelberer, Menansili A. Mejooli, Qiang Huang, Shengli Ding, David G. Kirsch, Diego V. Bohórquez, Nozomi Nishimura, Bradley B. Barth, Xiling Shen
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Performing intravital imaging of the colon in mouse models is challenging due to the colon’s anatomic location and motility. Here, the authors develop a murine colonic window for intravital chronic imaging that maximises long-term animal survival a
Externí odkaz: https://doaj.org/article/4870e24dd7e84d5da10cc08b011dd0cb
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2
Akademický článek
Intravital Microscopy of the Beating Murine Heart to Understand Cardiac Leukocyte Dynamics
Autor: Nathaniel H. Allan-Rahill, Michael R. E. Lamont, William M. Chilian, Nozomi Nishimura, David M. Small
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Cardiovascular disease is the leading cause of worldwide mortality. Intravital microscopy has provided unprecedented insight into leukocyte biology by enabling the visualization of dynamic responses within living organ systems at the cell-scale. The
Externí odkaz: https://doaj.org/article/1a4b440a40e042eeafa9cad2a59f75eb
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3
Akademický článek
Simultaneous optical and electrical in vivo analysis of the enteric nervous system
Autor: Nikolai Rakhilin, Bradley Barth, Jiahn Choi, Nini L. Muñoz, Subhash Kulkarni, Jason S. Jones, David M. Small, Yu-Ting Cheng, Yingqiu Cao, Colleen LaVinka, Edwin Kan, Xinzhong Dong, Michael Spencer, Pankaj Pasricha, Nozomi Nishimura, Xiling Shen
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
The enteric nervous system (ENS) plays a key role in regulating gut motility and homeostasis yet it remains a challenging system to record from. Here, the authors develop a novel abdominal window permitting simultaneous optical and electrical recordi
Externí odkaz: https://doaj.org/article/4b4722d9119741f99ce5fe47d5448f2b
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4
Akademický článek
In Vivo Calcium Imaging of Cardiomyocytes in the Beating Mouse Heart With Multiphoton Microscopy
Autor: Jason S. Jones, David M. Small, Nozomi Nishimura
Publikováno v: Frontiers in Physiology, Vol 9 (2018)
Background: Understanding the microscopic dynamics of the beating heart has been challenging due to the technical nature of imaging with micrometer resolution while the heart moves. The development of multiphoton microscopy has made in vivo, cell-res
Externí odkaz: https://doaj.org/article/488bdcedd9ec40ac9524f321e43345d6
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5
Akademický článek
Genetically engineered mice for combinatorial cardiovascular optobiology
Autor: Frank K Lee, Jane C Lee, Bo Shui, Shaun Reining, Megan Jibilian, David M Small, Jason S Jones, Nathaniel H Allan-Rahill, Michael RE Lamont, Megan A Rizzo, Sendoa Tajada, Manuel F Navedo, Luis Fernando Santana, Nozomi Nishimura, Michael I Kotlikoff
Publikováno v: eLife, Vol 10 (2021)
Optogenetic effectors and sensors provide a novel real-time window into complex physiological processes, enabling determination of molecular signaling processes within functioning cellular networks. However, the combination of these optical tools in
Externí odkaz: https://doaj.org/article/1b8cb82950fd45838080d740449051eb
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8
Genetically engineered mice for combinatorial cardiovascular optobiology
Autor: Michael I. Kotlikoff, Shaun Reining, Manuel F. Navedo, Jason S. Jones, David M. Small, Megan A. Rizzo, Bo Shui, Nozomi Nishimura, Nathaniel H. Allan-Rahill, Megan Jibilian, Luis Fernando Santana, Sendoa Tajada, Michael R. E. Lamont, Frank K. Lee, Jane C. Lee
Publikováno v: eLife
eLife, Vol 10 (2021)
Rationale: Optogenetic effectors and sensors provide a novel real-time window into complex physiological processes, enabling determination of molecular signaling processes within functioning cellular networks. The effective combination of these optic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9644e2560d7cacf543df9470f0f62595
https://escholarship.org/uc/item/0rx691mc
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10
Intravital Microscopy of the Beating Murine Heart to Understand Cardiac Leukocyte Dynamics
Autor: Nozomi Nishimura, William M. Chilian, Michael R. E. Lamont, David M. Small, Nathaniel H. Allan-Rahill
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Cardiovascular disease is the leading cause of worldwide mortality. Intravital microscopy has provided unprecedented insight into leukocyte biology by enabling the visualization of dynamic responses within living organ systems at the cell-scale. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134bc124d2da6d3e2634277312ff3b5a
https://www.frontiersin.org/article/10.3389/fimmu.2020.00092/full
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