Zobrazeno 1 - 10
of 22
pro vyhledávání: '"David M. Schwope"'
Publikováno v:
Journal of Addiction Medicine.
Publikováno v:
Journal of Analytical Toxicology. 42:512-517
Cocaine (COC) is widely abused and associated with significant adverse effects. Forensic and clinical laboratories often test for COC intake through detection of the primary metabolite, benzoylecgonine (BZE) in urine. Testing for BZE alone may result
Background: Identification of drug-drug interactions (DDIs) typically relies on patient medication lists which are prone to inaccuracies. This study describes use of a mass spectrometry test to detect recently ingested substances in urine with subseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844e2b08f6b02dde734ccc62869527d7
Autor:
David L. Black, Yale H. Caplan, David M. Schwope, Rebecca Heltsley, Edward J. Cone, Anne Z. DePriest
Publikováno v:
Journal of Analytical Toxicology. 38:513-518
Zolpidem (Ambien(®)) is the most prescribed insomnia treatment in the USA; however, little is known about zolpidem metabolite excretion in chronic pain patients. As zolpidem is extensively metabolized in vivo to zolpidem 4-phenyl carboxylic acid (ZC
Autor:
Deanna L. Kelly, Jennifer R. Schroeder, Denis Bonnet, Eugene W. Schwilke, Marilyn A. Huestis, Catherine Ortemann-Renon, David A. Gorelick, David M. Schwope, Robert S. Goodwin
Publikováno v:
The American Journal on Addictions. 22:510-514
Background and Objectives Δ9-tetrahydrocannabinol (THC) promotes sleep in animals; clinical use of THC is associated with somnolence. Human laboratory studies of oral THC have not shown consistent effects on sleep. We prospectively evaluated self-re
Autor:
Eugene W. Schwilke, Marilyn A. Huestis, Deanna L. Kelly, David A. Gorelick, David M. Schwope, Erin L. Karschner, Robert S. Goodwin
Publikováno v:
Drug and Alcohol Dependence. 125:313-319
Determining time since last cannabis/Δ9-tetrahydrocannabinol (THC) exposure is important in clinical, workplace, and forensic settings. Mathematical models calculating time of last exposure from whole blood concentrations typically employ a theoreti
Autor:
Marilyn A. Huestis, David M. Schwope, Allan J. Barnes, Dayong Lee, David A. Gorelick, Garry Milman
Publikováno v:
Clinical Chemistry. 58:1101-1109
BACKGROUND Defining cannabinoid stability in authentic oral fluid (OF) is critically important for result interpretation. There are few published OF stability data, and of those available, all employed fortified synthetic OF solutions or elution buff
Publikováno v:
Clinica Chimica Acta. 413:765-770
Background ∆9-Tetrahydrocannabinol (THC) in oral fluid (OF) implies cannabis intake, but eliminating passive exposure and improving interpretation of test results requires additional research. Methods Ten adult cannabis users smoked ad libitum one
Autor:
Robert S. Goodwin, David A. Gorelick, Eugene W. Schwilke, Marilyn A. Huestis, William D. Darwin, David M. Schwope, Deanna L. Kelly, Garry Milman
Publikováno v:
Clinical Chemistry. 57:1597-1606
BACKGROUND Oral fluid (OF) testing is increasingly important for drug treatment, workplace, and drugged-driving programs. There is interest in predicting plasma or whole-blood concentrations from OF concentrations; however, the relationship between t
Autor:
Garry Milman, Eugene W. Schwilke, David M. Schwope, Robert S. Goodwin, Deana L. Kelly, Allan J. Barnes, David A. Gorelick, Marilyn A. Huestis
Publikováno v:
Analytical and Bioanalytical Chemistry. 401:599-607
Oral fluid (OF) is an increasingly accepted matrix for drug testing programs, but questions remain about its usefulness for monitoring cannabinoids. Expectorated OF specimens (n = 360) were obtained from 10 adult daily cannabis smokers before, during