Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David M. Raiser"'
Publikováno v:
Am J Respir Cell Mol Biol
Autor:
Benjamin L. Ebert, Johan Flygare, Kavitha Siva, Yi Zhou, Jessica M. Humphries, Leonard I. Zon, Megan C. Blair, Linda T. Vo, Alison M. Taylor, Arish N Shah, Katherine E. McGrath, Vijay G. Sankaran, Emma Stillman, Sergei Doulatov, David M. Raiser, Iris T. Chan, George Q. Daley, Anindita Basak, Elizabeth R. Macari, Eliezer Calo, Richard I. Gregory, Blanche P. Alter, Mehdi Pirouz
Publikováno v:
PMC
Sci Transl Med
Sci Transl Med
© 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works Diamond-Blackfan anemia (DBA) is a rare hematopoietic disease characterized by a block in re
Autor:
Benjamin L. Ebert, Ram Ajore, David M. Raiser, Gordon Saksena, Steven R. Ellis, Bernd Boidol, Brenton G. Mar, Magnus Jöud, Marie McConkey, David M. Weinstock, Scott A. Armstrong, Björn Nilsson
Publikováno v:
EMBO Molecular Medicine. 9:498-507
Heterozygous inactivating mutations in ribosomal protein genes (RPGs) are associated with hematopoietic and developmental abnormalities, activation of p53, and altered risk of cancer in humans and model organisms. Here we performed a large‐scale an
Autor:
Arati Khanna-Gupta, Anupama Narla, A. Thomas Look, Benjamin L. Ebert, Nancy Berliner, David M. Raiser, Slater N. Hurst, Elspeth Payne, Nirmalee Abayasekara
Publikováno v:
British Journal of Haematology. 167:524-528
Haploinsufficiency of ribosomal proteins (RPs) and upregulation of the tumour suppressor TP53 have been shown to be the common basis for the anaemia observed in Diamond Blackfan anaemia and 5q- myelodysplastic syndrome. We previously demonstrated tha
Autor:
Allison N. Lau, Muhammad Aslam, Joo-Hyeon Lee, Eva Leder, Laura E. Fredenburgh, Kristen A. Tropea, Stella Kourembanas, David M. Raiser, Vivek Balasubramaniam, Carla F. Kim, S. Alex Mitsialis
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 302:L829-L837
Bronchopulmonary dysplasia (BPD) remains a major complication of prematurity resulting in significant morbidity and mortality. The pathology of BPD is multifactorial and leads to alveolar simplification and distal lung injury. Previous studies have s
Autor:
Katherine McGrath, Kavitha Siva, Alison M. Taylor, Johan Flygare, Benjamin L. Ebert, David M. Raiser, Leonard I. Zon, Jessica M Humphries, Elizabeth R Macari
Publikováno v:
Blood. 128:332-332
Ribosomal protein (RP) mutations are found in many diseases, including Diamond Blackfan anemia (DBA), where defective erythropoiesis, craniofacial abnormalities and increased cancer risk are major complications. RP mutations are thought to cause p53
Publikováno v:
Leukemialymphoma. 55(3)
More than a decade has passed since the initial identification of ribosomal protein gene mutations in patients with Diamond-Blackfan anemia (DBA), a hematologic disorder that became the founding member of a class of diseases known as ribosomopathies.
Autor:
Johan Flygare, Elizabeth R Macari, Jessica M Humphries, Alison M. Taylor, David M. Raiser, Kavitha Siva, Leonard I. Zon, Katherine McGrath, Benjamin L. Ebert
Publikováno v:
Blood. 126:672-672
Ribosomal protein (RP) mutations are found in many diseases, including Diamond Blackfan anemia (DBA), where defective erythropoiesis, craniofacial abnormalities and increased cancer risk are major complications. RP mutations cause p53 activation thro
Autor:
Carla F. Kim, Bethany E. Schaffer, Caitlin M. Roake, Kwok-Kin Wong, Mei-Chih Liang, Anne Flore Zmoos, Kwon-Sik Park, Rebecca R. Roach, Zandra E. Walton, Christina Kriegel, Julien Sage, David M. Raiser, Raffaella Zamponi, Stephen J. Curtis
Small cell lung carcinoma (SCLC) is a neuroendocrine subtype of lung cancer that affects more than 200,000 people worldwide every year with a very high mortality rate. Here, we used a mouse genetics approach to characterize the cell of origin for SCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8189c612e15eb42207d1d9abb78d546
https://europepmc.org/articles/PMC3219544/
https://europepmc.org/articles/PMC3219544/
Autor:
David M. Raiser, Carla F. Kim
Publikováno v:
Stem cells (Dayton, Ohio). 27(3)
In two separate articles published in this issue, Teisanu et al. and McQualter et al. report the use of flow cytometry and cell sorting to identify putative bronchiolar stem cells that are low in expression for the cell surface marker Sca-1 yet negat