Zobrazeno 1 - 10
of 11
pro vyhledávání: '"David M. Putman"'
Autor:
Daniela F Quail, Guihua Zhang, Logan A Walsh, Gabrielle M Siegers, Dylan Z Dieters-Castator, Scott D Findlay, Heather Broughton, David M Putman, David A Hess, Lynne-Marie Postovit
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48237 (2012)
Breast cancers expressing human embryonic stem cell (hESC)-associated genes are more likely to progress than well-differentiated cancers and are thus associated with poor patient prognosis. Elevated proliferation and evasion of growth control are sim
Externí odkaz:
https://doaj.org/article/7915dbe6ff8a45268257ce18fb1d04f6
Autor:
Gilles A. Lajoie, Stephen E. Sherman, David M. Putman, Miljan Kuljanin, Tyler T. Cooper, David A. Hess
Publikováno v:
Paediatrics Publications
During culture expansion, multipotent mesenchymal stromal cells (MSCs) differentially express aldehyde dehydrogenase (ALDH), an intracellular detoxification enzyme that protects long-lived cells against oxidative stress. Thus, MSC selection based on
Autor:
Marcelo Cypel, Stephen C. Juvet, A. Duong, David M. Putman, Tereza Martinu, Shaf Keshavjee, G.C. Madu, Jonathan C. Yeung
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S150
Purpose Lung transplantation (LTx) is limited by the scarcity of suitable donor lungs. One option to expand the donor pool is the use of donation after circulatory death (DCD) lungs. Additionally, ex vivo lung perfusion (EVLP) allows for evaluation a
Autor:
Gillian I. Bell, Tyler T. Cooper, Ayesh K. Seneviratne, Stephen E. Sherman, David A. Hess, David M. Putman
Publikováno v:
Paediatrics Publications
Human umbilical cord blood (UCB) hematopoietic progenitor cells (HPC) purified for high aldehyde dehydrogenase activity (ALDHhi) stimulate islet regeneration after transplantation into mice with streptozotocin-induced β cell deletion. However, ALDHh
Autor:
Mark Hewitt, Ayesh K. Seneviratne, Stephen E. Sherman, David M. Putman, David A. Hess, Gillian I. Bell, Tyler T. Cooper
Publikováno v:
Paediatrics Publications
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Uncompromised by chronic disease-related comorbidities, human umbilical cord blood (UCB) progenitor cells with high aldehyde dehydrogenase activity (ALDHhi cells) stimulate blood vessel regeneration after intra-muscular transplantation. However, impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332679103418898caf62303f570a0af2
https://ir.lib.uwo.ca/context/paedpub/article/2917/viewcontent/522.pdf
https://ir.lib.uwo.ca/context/paedpub/article/2917/viewcontent/522.pdf
Autor:
Marcelo Cypel, Manyin Chen, David M. Putman, T. Kanou, Y. Watanabe, Akihiro Ohsumi, K. Boonstra, Tereza Martinu, Shaf Keshavjee, Stephen C. Juvet
Publikováno v:
The Journal of Heart and Lung Transplantation. 36:S376
Autor:
David M. Putman, David A. Hess
Publikováno v:
Current Protocols in Stem Cell Biology
This unit describes the isolation and application of human umbilical cord blood progenitor cells to modulate vascular regenerative functions using in vitro co-culture systems and in vivo transplantation models. Using aldehyde dehydrogenase as a marke
Publikováno v:
Paediatrics Publications
Umbilical cord blood (UCB) represents a readily available source of hematopoietic and endothelial precursors at early ontogeny. Understanding the proangiogenic functions of these somatic progenitor subtypes after transplantation is integral to the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944c8eea597357cfa131328dcb2e8277
https://ir.lib.uwo.ca/context/paedpub/article/3706/viewcontent/1373.pdf
https://ir.lib.uwo.ca/context/paedpub/article/3706/viewcontent/1373.pdf
Publikováno v:
Paediatrics Publications
Aims/hypothesis We sought to investigate the stimulation of islet regeneration by transplanted human umbilical cord blood (UCB) cells purified according to high aldehyde dehydrogenase (ALDH) activity (ALDHhi), a conserved characteristic of multiple p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049cd5558b1c45cc95ac17a74828f025
https://ir.lib.uwo.ca/paedpub/2108
https://ir.lib.uwo.ca/paedpub/2108
Publikováno v:
Regenerative Therapy Using Blood-Derived Stem Cells ISBN: 9781617794704
Cell sorting based on high aldehyde dehydrogenase (ALDH) activity has emerged as a clinically applicable method to purify human bone marrow (BM) and umbilical cord blood (UCB) progenitors based on a conserved stem cell function. Although rare, ALDHhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb64100d13202d7b88f36fbcdb351bef
https://doi.org/10.1007/978-1-61779-471-1_3
https://doi.org/10.1007/978-1-61779-471-1_3