Zobrazeno 1 - 10
of 106
pro vyhledávání: '"David M. Pierce"'
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 1, Pp 100233- (2022)
Objective: We recently initiated microcracks, i.e. micron-scale cracks in the collagen networks of cartilage, using both single low-energy impacts and unconfined, cyclic compressions. We also tracked the propagation of microcracks after cyclic compre
Externí odkaz:
https://doaj.org/article/4f0af919bb974ac7bef126281aebd594
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 4, Pp 100086- (2020)
Summary: Objective: We aimed to directly quantify the zone-specific evolution in morphology of collagen fibers and networks in human cartilage during the progression of early osteoarthritis. Collagen fibers exhibit depth-dependent orientations and di
Externí odkaz:
https://doaj.org/article/85166119a9fe4ae2a1822f43df9f2196
Publikováno v:
Bioengineering, Vol 7, Iss 4, p 152 (2020)
Abnormal colorectal biomechanics and mechanotransduction associate with an array of gastrointestinal diseases, including inflammatory bowel disease, irritable bowel syndrome, diverticula disease, anorectal disorders, ileus, and chronic constipation.
Externí odkaz:
https://doaj.org/article/73e0e1a10f6b480dac625d831a718994
Publikováno v:
Bioengineering, Vol 7, Iss 4, p 130 (2020)
Many lower gastrointestinal diseases are associated with altered mechanical movement and deformation of the large intestine, i.e., the colon and rectum. The leading reason for patients’ visits to gastrointestinal clinics is visceral pain, which is
Externí odkaz:
https://doaj.org/article/2e4c1c4b5eea411da013fe809cf88d56
Autor:
Stephanie E. Schneider, Adrienne K. Scott, Benjamin Seelbinder, Courtney Van Den Elzen, Robert L. Wilson, Emily Y. Miller, Quinn I. Beato, Soham Ghosh, Jeanne E. Barthold, Jason Bilyeu, Nancy C. Emery, David M. Pierce, Corey P. Neu
Publikováno v:
Acta Biomaterialia. 163:339-350
Cells are continuously exposed to dynamic environmental cues that influence their behavior. Mechanical cues can influence cellular and genomic architecture, gene expression, and intranuclear mechanics, providing evidence of mechanosensing by the nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dfba7e3b193c43b53442f22a115250
https://doi.org/10.1016/j.actbio.2022.07.002
https://doi.org/10.1016/j.actbio.2022.07.002
Autor:
Borja Rodriguez‐Vila, Vera Gonzalez‐Hospital, Enrique Puertas, Juan‐Jose Beunza, David M. Pierce
Publikováno v:
Journal of Orthopaedic Research.
In this study we aimedto democratize access to Convolutional Neural Networks (CNN) for segmenting cartilage volumes, generating state-of-the-art results for specialized, real-world applications in hospitals and research. Segmentation of cross-section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95edada54c8d497e51ca5fbc1b3304fd
https://doi.org/10.1002/jor.25509
https://doi.org/10.1002/jor.25509
Autor:
Bin Feng, David M. Pierce
Publikováno v:
Visceral Pain ISBN: 9783031257018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e75695e9c302f450b0cf315f1f223645
https://doi.org/10.1007/978-3-031-25702-5_7
https://doi.org/10.1007/978-3-031-25702-5_7
Publikováno v:
Journal of magnetic resonance imaging : JMRIReferences.
Healthy articular cartilage presents structural gradients defined by distinct zonal patterns through the thickness, which may be disrupted in the pathogenesis of several disorders. Analysis of textural patterns using quantitative MRI data may identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b51e9031006854f1bf7eaa8fc77d48
https://pubmed.ncbi.nlm.nih.gov/36285338
https://pubmed.ncbi.nlm.nih.gov/36285338
Autor:
David M. Pierce
Publikováno v:
Archive of Applied Mechanics. 92:513-528
Finite element (FE) modeling plays a well-established and increasingly significant role in analyses of articular cartilage at the organ, tissue, and cell scales: for example understanding the functional relationships among constituents, microstructur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b76cbd08e206133bbc407731c2ad0e4a
https://doi.org/10.1007/s00419-021-01959-5
https://doi.org/10.1007/s00419-021-01959-5
Publikováno v:
Computer Methods and Programs in Biomedicine. 231:107419
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c9ce3bb9a0f6518904553246a183013
https://doi.org/10.1016/j.cmpb.2023.107419
https://doi.org/10.1016/j.cmpb.2023.107419