Zobrazeno 1 - 10
of 164
pro vyhledávání: '"David M. Perrin"'
Autor:
Joseph Lau, Jinhe Pan, Etienne Rousseau, Carlos F. Uribe, Sudhakara Reddy Seelam, Brent W. Sutherland, David M. Perrin, Kuo-Shyan Lin, François Bénard
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Introduction [18F]AmBF3-TATE is a somatostatin agonist that selectively binds to somatostatin receptor subtype 2 (SSTR2). For clinical translation, pharmacokinetics, radiation dosimetry, and acute toxicity of [18F]AmBF3-TATE were assessed wi
Externí odkaz:
https://doaj.org/article/24c809a2cd514b37b99d494b1b93c70c
Publikováno v:
Molecules, Vol 20, Iss 8, Pp 13591-13602 (2015)
To expand the chemical functionality of DNAzymes and aptamers, several new modified deoxyuridine triphosphates have been synthesized. An important precursor that enables this aim is 5-aminomethyl dUTP, whereby the pendent amine serves as a handle for
Externí odkaz:
https://doaj.org/article/42a39051e6514d109594028d017f94b9
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 66:130-137
Autor:
Christopher M. Overall, David M. Perrin, François Bénard, Thomas J. Ruth, Michael J. Adam, Shoukat Dedhar, Reinhild Kappelhoff, Curtis Harwig, Richard Ting, Philipp F. Lange, Yuanmei Lou, Ying Li, Caroline L. Bellac, Ulrich auf dem Keller
Supplementary Figures 1-2, Methods from Novel Matrix Metalloproteinase Inhibitor [18F]Marimastat-Aryltrifluoroborate as a Probe for In vivo Positron Emission Tomography Imaging in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b46e65311654a53696d5c03dabcfe8e
https://doi.org/10.1158/0008-5472.22384635.v1
https://doi.org/10.1158/0008-5472.22384635.v1
Publikováno v:
Angewandte Chemie International Edition. 62
Publikováno v:
Angewandte Chemie. 135
Autor:
Alla Pryyma, David M. Perrin, Yong Jia Bu, Helen Merkens, Francois Benard, Zhengxing Zhang, Kaveh Matinkhoo
Publikováno v:
RSC Chemical Biology
Targeted cancer therapy represents a paradigm-shifting approach that aims to deliver a toxic payload selectively to target-expressing cells thereby sparing normal tissues the off-target effects associated with traditional chemotherapeutics. Since mos
Publikováno v:
Angewandte Chemie International Edition. 62
Autor:
Felipe Eltit, Nicole Robinson, Pak Lok Ivan Yu, Mitali Pandey, Jerome Lozada, Yubin Guo, Manju Sharma, Dogancan Ozturan, Laetitia Ganier, Eric Belanger, Nathan A. Lack, David M. Perrin, Michael E. Cox, S. Larry Goldenberg
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031261626
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7985325a1ca38d2208c4de6e0aed181
https://doi.org/10.1007/978-3-031-26163-3_16
https://doi.org/10.1007/978-3-031-26163-3_16
Autor:
Torsten Hechler, Andreas Pahl, Alexandra Braun, Kaveh Matinkhoo, Brandon Kato, Christoph Müller, Francesca Gallo, Antonio A. W. L. Wong, Charlie Wei, Chido M. Hambira, David M. Perrin
Publikováno v:
Chemistry – A European Journal. 27:10282-10292
Alpha-amanitin, an extremely toxic bicyclic octapeptide extracted from the death-cap mushroom, Amanita phalloides, is a highly selective allosteric inhibitor of RNA polymerase II. Following on growing interest in using this toxin as a payload in anti