Zobrazeno 1 - 10
of 183
pro vyhledávání: '"David M. Mutch"'
Autor:
Scott B. Maitland, Paula Brauer, David M. Mutch, Dawna Royall, Doug Klein, Angelo Tremblay, Caroline Rheaume, Khursheed Jeejeebhoy
Publikováno v:
BMC Primary Care, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Substantial variability in response to lifestyle interventions has been recognized for many years, and researchers have begun to disentangle sources of error from inherent differences in individual responsiveness. The objective of
Externí odkaz:
https://doaj.org/article/add7ed22b840479e9165faa080921acb
Autor:
Adam H. Metherel, Rodrigo Valenzuela, Brinley J. Klievik, Giulia Cisbani, Ruxandra D. Rotarescu, Melissa Gonzalez-Soto, Céline Cruciani-Guglielmacci, Sophie Layé, Christophe Magnan, David M. Mutch, Richard P. Bazinet
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 6, Pp 100548- (2024)
DHA is abundant in the brain where it regulates cell survival, neurogenesis, and neuroinflammation. DHA can be obtained from the diet or synthesized from alpha-linolenic acid (ALA; 18:3n-3) via a series of desaturation and elongation reactions occurr
Externí odkaz:
https://doaj.org/article/dc5d416deb604260a24530657c36dc62
Autor:
Ritchie Ly, Brittany C. MacIntyre, Stuart M. Philips, Chris McGlory, David M. Mutch, Philip Britz-McKibbin
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 11, Pp 100445- (2023)
Optimal dietary intake of omega-3 long-chain polyunsaturated fatty acids (n3-LCPUFAs) is critical to human health across the lifespan. However, omega-3 index (O3I) determination is not routinely assessed due to complicated procedures for n3-LCPUFA an
Externí odkaz:
https://doaj.org/article/81360f8065254cea869d070ef8691d17
Autor:
Chenxuan Wang, Barbora Hucik, Ousseynou Sarr, Liam H. Brown, Kyle R.D. Wells, Keith R. Brunt, Manabu T. Nakamura, Ewa Harasim-Symbor, Adrian Chabowski, David M. Mutch
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 6, Pp 100376- (2023)
The Δ-6 desaturase (D6D) enzyme is not only critical for the synthesis of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from α-linolenic acid (ALA), but recent evidence suggests that it also plays a role in adipocyte lipid metabolism a
Externí odkaz:
https://doaj.org/article/03285ef0270040c3b186ceb9e6e46e07
Autor:
Paula Brauer, Dawna Royall, Airu Li, Ariellia Rodrigues, Jennifer Green, Sharon Macklin, Alison Craig, Miranda Chan, Jennifer Pasanen, Lucie Brunelle, Rupinder Dhaliwal, Doug Klein, Angelo Tremblay, Caroline Rheaume, David M. Mutch, Khursheed Jeejeebhoy
Publikováno v:
BMC Nutrition, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Background Personalized diet counselling, as part of lifestyle change programs for cardiometabolic risk conditions (combinations of prediabetes or type 2 diabetes, hypertension, dyslipidemia and high waist circumference) has been shown to re
Externí odkaz:
https://doaj.org/article/19ddb248b860471fb7d854b9edf25f27
Autor:
Brittany C. MacIntyre, Meera Shanmuganathan, Shannon L. Klingel, Zachary Kroezen, Erick Helmeczi, Na-Yung Seoh, Vanessa Martinez, Adrian Chabowski, Zeny Feng, Philip Britz-McKibbin, David M. Mutch
Publikováno v:
Metabolites, Vol 13, Iss 10, p 1071 (2023)
The Omega-3 Index (O3I) reflects eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) content in erythrocytes. While the O3I is associated with numerous health outcomes, its widespread use is limited. We investigated whether urinary metabolites
Externí odkaz:
https://doaj.org/article/b8e4897cd64c4913a62d68856c4b1663
Autor:
Barbora Hucik, Andrew J. Lovell, Evan M. Hoecht, Daniel T. Cervone, David M. Mutch, David J. Dyck
Publikováno v:
Adipocyte, Vol 10, Iss 1, Pp 338-349 (2021)
Ghrelin is released from the stomach as an anticipatory signal prior to a meal and decreases immediately after. Previous research has shown that both acylated (AG) and unacylated (UnAG) ghrelin blunt adrenoreceptor-stimulated lipolysis in rat white a
Externí odkaz:
https://doaj.org/article/33c3d66a0be345f0900d43c6c9e792b2
Autor:
Chenxuan Wang, Jessica Murphy, Kerri Z. Delaney, Natalie Khor, José A. Morais, Michael A. Tsoukas, Dana E. Lowry, David M. Mutch, Sylvia Santosa
Publikováno v:
Adipocyte, Vol 10, Iss 1, Pp 124-130 (2021)
Fatty acid desaturase 1 (FADS1) polymorphisms alter fatty acid content in subcutaneous adipose tissue (SAT); however, existing evidence is limited and conflicting regarding the association between FADS1 variants and SAT inflammatory status. To advanc
Externí odkaz:
https://doaj.org/article/4e0bf114784a455698b0aeddd7b45508
Autor:
Justine Keathley, Véronique Garneau, Valérie Marcil, David M. Mutch, Julie Robitaille, Iwona Rudkowska, Gabriela Sofian, Sophie Desroches, Marie-Claude Vohl
Publikováno v:
Frontiers in Nutrition, Vol 8 (2022)
BackgroundA recent systematic review, which used the GRADE methodology, concluded that there is strong evidence for two gene-diet associations related to omega-3 and plasma triglyceride (TG) responses. Systematic reviews can be used to inform the dev
Externí odkaz:
https://doaj.org/article/3641d5799f3f4771895b74152b466cae
Autor:
Angelo Tremblay, Marie-Pier Bélanger, Rupinder Dhaliwal, Paula Brauer, Dawna Royall, David M. Mutch, Caroline Rhéaume
Publikováno v:
Archives of Public Health, Vol 78, Iss 1, Pp 1-12 (2020)
Résumé Contexte Le syndrome métabolique (SMet) est un problème de santé caractérisé par des anomalies métaboliques prédisant un risque accru de développer une maladie cardiovasculaire (MCV) et un diabète de type 2 (DT2). Il peut être rés
Externí odkaz:
https://doaj.org/article/76c89a927d5344eb8f553b69fab34b7d