Zobrazeno 1 - 10
of 96
pro vyhledávání: '"David M. Maslove"'
Autor:
John Muscedere, MD, David M. Maslove, MD, MS, Christopher J. Barden, PhD, Donald F. Weaver, MD, PhD, J. Gordon Boyd, MD, PhD, Stephanie Sibley, MD, MS, Tracy Boyd, Oleksa Rewa, MD, MSc, Martin Albert, Marios Roussos, MD, MPH, Patrick A. Norman, MSc, Andrew G. Day, MSc, for the Canadian Critical Care Trials Group
Publikováno v:
Critical Care Explorations, Vol 6, Iss 2, p e1045 (2024)
OBJECTIVES:. Respiratory failure secondary to COVID-19 is associated with morbidity and mortality. Current anti-inflammatory therapies are effective but are given systemically and have significant side effects. Furosemide has anti-inflammatory proper
Externí odkaz:
https://doaj.org/article/75bfeef1c7a44b88adb6c1fa800a9118
Autor:
Natasha A. Jawa, Samuel A. Silver, Rachel M. Holden, Stephen H. Scott, Andrew G. Day, Patrick A. Norman, Benjamin Y. M. Kwan, David M. Maslove, John Muscedere, J. Gordon Boyd
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 10 (2023)
Background: Acute kidney injury (AKI) resulting in kidney replacement therapy is rising among critically ill adults. Long-term kidney replacement therapy and critical illness are independently linked to acute and prolonged cognitive impairment, and s
Externí odkaz:
https://doaj.org/article/23f17f7e323949cba5072152f7127dcf
Autor:
Brian Chen, David M. Maslove, Jeffrey D. Curran, Alexander Hamilton, Philip R. Laird, Parvin Mousavi, Stephanie Sibley
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Background Atrial fibrillation (AF) is the most common cardiac arrhythmia in the intensive care unit and is associated with increased morbidity and mortality. New-onset atrial fibrillation (NOAF) is often initially paroxysmal and fleeting, m
Externí odkaz:
https://doaj.org/article/7e427bcb649d4f92aebef7860f4d104d
Autor:
Brian J. Laight, Natasha A. Jawa, Kathrin Tyryshkin, David M. Maslove, J. Gordon Boyd, Peter A. Greer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSepsis is a result of initial over-activation of the immune system in response to an infection or trauma that results in reduced blood flow and life-threatening end-organ damage, followed by suppression of the immune system that prevents
Externí odkaz:
https://doaj.org/article/1ac1ce10d21644db81c691534adf5743
Publikováno v:
Critical Care Explorations, Vol 4, Iss 12, p e0814 (2022)
OBJECTIVES:. High-frequency data streams of vital signs may be used to generate individualized hemodynamic targets for critically ill patients. Central to this precision medicine approach to resuscitation is our ability to screen these data streams f
Externí odkaz:
https://doaj.org/article/3c9f291dfdff4f7f8ff799d7a4b4fc2a
Autor:
Gabrielle Levin, J. Gordon Boyd, Andrew Day, Miranda Hunt, David M. Maslove, Patrick Norman, Nicole O’Callaghan, Stephanie Sibley, John Muscedere
Publikováno v:
Intensive Care Medicine Experimental, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Introduction Immunological dysfunction is common in critically ill patients but its clinical significance and the optimal method to measure it are unknown. The level of tumor necrosis factor alpha (TNF-α) after ex-vivo whole blood stimulati
Externí odkaz:
https://doaj.org/article/95019cba79f24712a6d82a5c9c4391f7
Autor:
Ross T. Prager, MD, Michael T. Pratte, BSc, Laura H. Thompson, PhD, Kylie E. McNeill, PhD, Christina Milani, MSc, David M. Maslove, MD, MSc, Shannon M. Fernando, MD, MSc, Kwadwo Kyeremanteng, MD, MBA
Publikováno v:
Critical Care Explorations, Vol 3, Iss 12, p e0596 (2021)
IMPORTANCE:. Prognostication following ICU admission can often be determined based on known risk factors, including demographics and illness severity; however, little is known about outcomes of patients deemed to be “low-risk” at the time of hosp
Externí odkaz:
https://doaj.org/article/f521e11ada37481fbc8a4790f8e31d9f
Autor:
Michael D. Wood, Jill A. Jacobson, David M. Maslove, John G. Muscedere, J. Gordon Boyd, The Cerebral Oxygenation and Neurological Outcomes Following Critical Illness (CONFOCAL) Research Group
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Background To maintain adequate oxygen delivery to tissue, resuscitation of critically ill patients is guided by assessing surrogate markers of perfusion. As there is no direct indicator of cerebral perfusion used in routine critical care, i
Externí odkaz:
https://doaj.org/article/f5905824a44547de8dd21e47cd95f9ed
Autor:
Ryan R. Kroll, Erica D. McKenzie, J. Gordon Boyd, Prameet Sheth, Daniel Howes, Michael Wood, David M. Maslove, for the WEARable Information Technology for hospital INpatients (WEARIT-IN) study group
Publikováno v:
Journal of Intensive Care, Vol 5, Iss 1, Pp 1-8 (2017)
Abstract Background Wearable devices generate signals detecting activity, sleep, and heart rate, all of which could enable detailed and near-continuous characterization of recovery following critical illness. Methods To determine the feasibility of u
Externí odkaz:
https://doaj.org/article/df91715f8de642b5a5a180c50cc3de6f
Publikováno v:
Critical Care, Vol 21, Iss 1, Pp 1-9 (2017)
Abstract Precision medicine is increasingly touted as a groundbreaking new paradigm in biomedicine. In the ICU, the complexity and ambiguity of critical illness syndromes have been identified as fundamental justifications for the adoption of a precis
Externí odkaz:
https://doaj.org/article/3b1f2e069d2141b29d33427647de443b