Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David M. Marsden"'
Autor:
Rebecca L. Nicholson, Gemma L. Thomas, James T. Hodgkinson, David M. Marsden, Martin Welch, George P. C. Salmond, David R. Spring, Xianbin Su, Richard J. Spandl
Publikováno v:
Synlett. 2008:2122-2126
The synthesis of bacterial quorum-sensing regulator N-(3-oxohexanoyl)-L-homoserine lactone (OHHL) and biotin-tagged OHHL is reported. The latter will be applied to developing a general method to address the 'target identification problem' in chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcf09315d4ed6f031c2d6e2351680fdc
https://doi.org/10.1055/s-2008-1077978
https://doi.org/10.1055/s-2008-1077978
Publikováno v:
Tetrahedron Letters. 51:5930-5932
A tetrafluorophenol acrylamide monomer unit was synthesised, co-polymerised and grafted onto a glass slide to form individual gel spots. As a proof of principle study, a small library of amides was rapidly synthesised within these gel spots using ‘
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fe9479766caf577961f860aa174918
https://doi.org/10.1016/j.tetlet.2010.09.024
https://doi.org/10.1016/j.tetlet.2010.09.024
Autor:
David M. Marsden, Robert C. Glen, Freija G. Glansdorp, Gemma L. Thomas, Emma E. Wyatt, Richard J. Spandl, Rebecca L. Nicholson, Andreas Bender, David R. Spring, Warren R. J. D. Galloway, Suzanne Fergus
Publikováno v:
Ernst Schering Research Foundation Workshop ISBN: 9783540278658
This article covers the diversity-oriented synthesis (DOS) of small molecules in order to generate a collection of pure compounds that are attractive for lead generation in a phenotypic, high-throughput screening approach useful for chemical genetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::838406e84f999f4c28b06b1e8cb2e2e6
https://doi.org/10.1007/978-3-540-37635-4_4
https://doi.org/10.1007/978-3-540-37635-4_4
Autor:
Hannah F. Sore, David M. Marsden, Mette E. Skindersoe, Martin Welch, Mark Ladlow, Rebecca L. Nicholson, George P. C. Salmond, David R. Spring, Warren R. J. D. Galloway, Michael Givskov
Publikováno v:
Organic & Biomolecular Chemistry. 8:5313
The screening of large arrays of drug-like small-molecules was traditionally a time consuming and resource intensive task. New methodology developed within our laboratories provides an attractive low cost, 3D microarray-assisted screening platform th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ceb032772920dd7caba402a456a66c
https://doi.org/10.1039/c0ob00300j
https://doi.org/10.1039/c0ob00300j
Publikováno v:
Chemical Communications; Nov2009, Vol. 2009 Issue 46, p7107-7109, 3p