Zobrazeno 1 - 10
of 133
pro vyhledávání: '"David M. Markovitz"'
Autor:
Thao Ngoc Huynh, Jody Toperzer, Allison Scherer, Anne Gumina, Tonya Brunetti, Michael K. Mansour, David M. Markovitz, Brian C. Russo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The intermediate filament vimentin is present in immune cells and is implicated in proinflammatory immune responses. Whether and how it supports antimicrobial activities of neutrophils are not well established. Here, we developed an immortalized neut
Externí odkaz:
https://doaj.org/article/88eeae99cf5346b9aac4248b852902b5
Autor:
Souren Paul, Mark H. Kaplan, Dinesh Khanna, Preston M. McCourt, Anjan K. Saha, Pei-Suen Tsou, Mahek Anand, Alexander Radecki, Mohamad Mourad, Amr H. Sawalha, David M. Markovitz, Rafael Contreras-Galindo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Fibrosis of the skin plays an important role in scleroderma. Here the authors demonstrate genetic and epigenetic abnormalities at the centromere that affect the replication of the chromosomes, resulting in activation of pathways involved in inflammat
Externí odkaz:
https://doaj.org/article/d5eaf6cdd6504e8d8ebc8070af2ffb48
Autor:
Natalie H. Matthews, MD, MPhil, Cayla M. Pichan, BS, Alexandra C. Hristov, MD, David M. Markovitz, MD, Allison M. Darland, MD
Publikováno v:
JAAD Case Reports, Vol 29, Iss , Pp 62-63 (2022)
Externí odkaz:
https://doaj.org/article/6b5e054546ff466b800994998fb12f9d
Autor:
Evelyn M. Covés-Datson, Steven R. King, Maureen Legendre, Michael D. Swanson, Auroni Gupta, Sandra Claes, Jennifer L. Meagher, Arnaud Boonen, Lihong Zhang, Birte Kalveram, Zoe Raglow, Alexander N. Freiberg, Mark Prichard, Jeanne A. Stuckey, Dominique Schols, David M. Markovitz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Lectins, carbohydrate-binding proteins, have been regarded as potential antiviral agents, as some can bind glycans on viral surface glycoproteins and inactivate their functions. However, clinical development of lectins has been stalled by th
Externí odkaz:
https://doaj.org/article/283392a3b205412094e2427caa1508b6
Autor:
Ilias Christodoulou, Ruyan Rahnama, Jonas W. Ravich, Jaesung Seo, Sergey N. Zolov, Andrew N. Marple, David M. Markovitz, Challice L. Bonifant
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
H84T-Banana Lectin (BanLec) CAR-NK cells bind high mannose glycosites that decorate the SARS-CoV-2 envelope, thereby decreasing cellular infection in a model of SARS-CoV-2. H84T-BanLec CAR-NK cells are innate effector cells, activated by virus. This
Externí odkaz:
https://doaj.org/article/e1a08cabdeee4585bd26b7c7a028c51f
Autor:
Nirit Mor-Vaknin, Anjan Saha, Maureen Legendre, Carmelo Carmona-Rivera, M Asif Amin, Bradley J. Rabquer, Marta J. Gonzales-Hernandez, Julie Jorns, Smriti Mohan, Srilakshmi Yalavarthi, Dave A. Pai, Kristine Angevine, Shelley J. Almburg, Jason S. Knight, Barbara S. Adams, Alisa E. Koch, David A. Fox, David R. Engelke, Mariana J. Kaplan, David M. Markovitz
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
DEK is a secreted protein abundant in the synovia of patients with juvenile idiopathic arthritis. Here the authors show DEK is important for neutrophil extracellular trap formation and joint inflammation, and demonstrate therapeutic efficacy of DEK-t
Externí odkaz:
https://doaj.org/article/2c912d0db4e646ad89d036163808223e
Autor:
Qi Xiao, Zhichun Wang, Dewight Williams, Pawaret Leowanawat, Mihai Peterca, Samuel E. Sherman, Shaodong Zhang, Daniel A. Hammer, Paul A. Heiney, Steven R. King, David M. Markovitz, Sabine André, Hans-Joachim Gabius, Michael L. Klein, Virgil Percec
Publikováno v:
ACS Central Science, Vol 2, Iss 12, Pp 943-953 (2016)
Externí odkaz:
https://doaj.org/article/3009908fbc0743e6ac8d56ab3c0ce45c
Autor:
Pallab Ghosh, Elizabeth M. Halvorsen, Dustin A. Ammendolia, Nirit Mor-Vaknin, Mary X. D. O’Riordan, John H. Brumell, David M. Markovitz, Darren E. Higgins
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Listeria monocytogenes is a facultative intracellular bacterial pathogen that is frequently associated with food-borne infection. Of particular concern is the ability of L. monocytogenes to breach the blood-brain barrier, leading to life-thr
Externí odkaz:
https://doaj.org/article/3987dc4dc043403987c170c9dc79fd39
Publikováno v:
Current Pharmaceutical Design. 27:4212-4222
Background: In December 2019, China announced the first case of an infection caused by an, until then, unknown virus: SARS-CoV-2. Since then, researchers have been looking for viable alternatives for the treatment and/or cure of viral infection. Amon
Autor:
James Ropa, Sarah Gutch, Lindsay Beasley, Paola Aguilar Neuville, Scott Cooper, Di Cao, Wouter van't Hof, Maureen Legendre, Mark Kaplan, David M Markovitz, Maegan L. Capitano
Publikováno v:
Blood. 140:8576-8577