Zobrazeno 1 - 10
of 74
pro vyhledávání: '"David M. Lyerly"'
Publikováno v:
ACS Infectious Diseases. 6:2818-2829
Clostridioides difficile is a dangerous human pathogen because it can grow to high numbers in the intestine, cause colitis with its potent toxins, and persist as spores. C. difficile infection (CDI) is the primary hospital-acquired infection in North
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f93b131798a857ba39e7674ba5acbc57
https://doi.org/10.1021/acsinfecdis.0c00290
https://doi.org/10.1021/acsinfecdis.0c00290
Autor:
Mary K Young, Jhansi L Leslie, Gregory R Madden, David M Lyerly, Robert J Carman, Matthew W Lyerly, David B Stewart, Mayuresh M Abhyankar, William A Petri
Publikováno v:
Open Forum Infectious Diseases. 9
Background The incidence of Clostridioides difficile infection (CDI) has increased over the past 2 decades and is considered an urgent threat by the Centers for Disease Control and Prevention. Hypervirulent strains such as ribotype 027, which possess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::668cfc949a3488dd0df99c36188fbe56
https://doi.org/10.1093/ofid/ofac001
https://doi.org/10.1093/ofid/ofac001
Autor:
David M. Lyerly, William A. Petri, Jhansi L. Leslie, Mayuresh M. Abhyankar, David B Stewart, Gregory R Madden, Robert J. Carman, Mary K Young
BackgroundThe incidence of Clostridioides difficile infection (CDI) has increased over the past two decades and is considered an urgent threat by the Centers for Disease Control. Hypervirulent strains such as ribotype 027, that possess genes for an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2346accde5540480b311f21e9815ddb
https://doi.org/10.1101/2021.07.30.21261256
https://doi.org/10.1101/2021.07.30.21261256
Autor:
Mary K, Young, Jhansi L, Leslie, Gregory R, Madden, David M, Lyerly, Robert J, Carman, Matthew W, Lyerly, David B, Stewart, Mayuresh M, Abhyankar, William A, Petri
Publikováno v:
Open forum infectious diseases. 9(3)
The incidence ofWe retrospectively tested stool from 215 CDI patients for CDT by enzyme-linked immunosorbent assay (ELISA). Stratifying patients by CDT status, we assessed if disease severity and clinical outcomes correlated with CDT positivity. Addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4eaa07c50b534d2c8013446a80c970a9
https://pubmed.ncbi.nlm.nih.gov/35146046
https://pubmed.ncbi.nlm.nih.gov/35146046
Autor:
Miseon Park, Megan F. Hiltonsmith, David M. Lyerly, Christopher W. Genheimer, Robert J. Carman, Fatemeh Rafii
Publikováno v:
Anaerobe. 15:244-248
To characterize the extent and diversity of moxifloxacin resistance among Clostridium difficile isolates recovered during a predominantly Anaerobe Reference Unit (ARU) ribotype 027-associated nosocomial outbreak of antibiotic associated diarrhea we m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66e985636b75efd2c253fccbafa7fe7
https://doi.org/10.1016/j.anaerobe.2009.09.009
https://doi.org/10.1016/j.anaerobe.2009.09.009
Autor:
David M. Lyerly, Steven M. Becker, Lisa Barroso, Thomas S. Vedvick, Steven G. Reed, William A. Petri, Eric R. Houpt, Xiaoti Guo
Publikováno v:
Infection and Immunity. 77:3909-3918
We have previously shown that vaccination with purifiedEntamoeba histolyticaGal/GalNAc lectin or recombinant subunits can protect mice from intestinal amebiasis upon intracecal challenge. In this study, we demonstrated with adoptive-transfer experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43142f69b26e23c2fa09a97d03d96521
https://doi.org/10.1128/iai.00487-09
https://doi.org/10.1128/iai.00487-09
Autor:
Ellie J. C. Goldstein, Limin Zheng, David M. Lyerly, Christopher W. Genheimer, Diane M. Citron, Robert J. Carman, Stephanie F. Sigmon
Publikováno v:
Anaerobe. 13:114-120
Amongst 25 extra-intestinal clinical isolates of Clostridium difficile, A(+)B(+) (72%) and A(-)B(+) (4%) toxigenic phenotypes, as well as the non-toxigenic phenotype (A(-)B(-)) (24%), were identified. The A(-)B(-) isolates did not express toxin, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e8336660e6152689cfd1d5418f74ea
https://doi.org/10.1016/j.anaerobe.2007.04.001
https://doi.org/10.1016/j.anaerobe.2007.04.001
Multicenter Evaluation of a New Screening Test That Detects Clostridium difficile in Fecal Specimens
Autor:
Limin Zheng, David M. Lyerly, K. Ye, Curt A. Gleaves, S. Perez, C. W. Genheimer, Stephen Young, Sue J. Kohlhepp, S. F. Keller, Robert J. Carman
Publikováno v:
Journal of Clinical Microbiology. 42:3837-3840
Clostridium difficile causes approximately 25% of nosocomial antibiotic-associated diarrheas and most cases of pseudomembranous colitis. We evaluated C. DIFF CHEK , a new screening test that detects glutamate dehydrogenase of C. difficile . Our resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e341a370c693cb4c9d20b0d53dfbbcb8
https://doi.org/10.1128/jcm.42.8.3837-3840.2004
https://doi.org/10.1128/jcm.42.8.3837-3840.2004
Autor:
William A. Petri, David M. Lyerly, Lauren A. Lockhart, Rhonda L. Wright, Carole L. Cramer, Lisa Barroso, Eric R. Houpt
Publikováno v:
Vaccine. 22:611-617
Prevention of intestinal infection by Entamoeba histolytica would block both invasive disease and parasite transmission. The amebic Gal/GalNAc lectin mediates parasite adherence to the colonic surface and fecal anti-lectin IgA is associated with prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7696e13f86d0790786a1f690a3afa21f
https://doi.org/10.1016/j.vaccine.2003.09.003
https://doi.org/10.1016/j.vaccine.2003.09.003
Autor:
Tracy D. Wilkins, David M. Lyerly
Publikováno v:
Journal of Clinical Microbiology. 41:531-534
More than 20 years ago, as Clostridium difficile was being established as the cause of pseudomembranous colitis and antibiotic-associated diarrhea (AAD), many clinical laboratories were using or beginning to use cycloserine-cefoxitin-fructose agar, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6aad736d199ada2cfc10688d2578554
https://doi.org/10.1128/jcm.41.2.531-534.2003
https://doi.org/10.1128/jcm.41.2.531-534.2003