Zobrazeno 1 - 10
of 55
pro vyhledávání: '"David M. Kofler"'
Autor:
Viktoria Golumba‐Nagy, Shuaifeng Yan, Eva Steinbach‐Knödgen, Jan Thiele, Ruth L. Esser, Thomas H. Haak, Anastasia Nikiforov, Anja Meyer, Tamina Seeger‐Nukpezah, David M. Kofler
Publikováno v:
Physiological Reports, Vol 11, Iss 19, Pp n/a-n/a (2023)
Abstract The JAK/STAT pathway plays a crucial role in the pathogenesis of rheumatoid arthritis (RA) and JAK inhibitors have emerged as a new group of effective drugs for RA treatment. Recently, high STAT3 levels have been associated with the upregula
Externí odkaz:
https://doaj.org/article/81438bdbe9c5496dade440d63be182ff
Autor:
Anne L. Astier, David M. Kofler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0cc15a12b73042e78cdff5b55f8b1573
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Regulatory T (Treg) cells are garnering increased attention in research related to autoimmune diseases, including rheumatoid arthritis (RA). They play an essential role in the maintenance of immune homeostasis by restricting effector T cell activity.
Externí odkaz:
https://doaj.org/article/89634c9a00084e9c8784d5f2a61ccf07
Autor:
Charlotte Klasen, Anja Meyer, Paula S. Wittekind, Iris Waqué, Schafiq Nabhani, David M. Kofler
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-13 (2019)
Abstract Background Th17 cells are involved in the pathogenesis of ankylosing spondylitis (AS). However, the mechanism underlying enhanced Th17 cell accumulation in AS remains unknown. The prostaglandin E2 receptor EP2/EP4 signaling pathway plays a c
Externí odkaz:
https://doaj.org/article/afbca042b73f4a15b7b24ca0dd21abb0
Autor:
Mara Dittrich-Salamon, Anja Meyer, Shuaifeng Yan, Eva Steinbach-Knödgen, Konstantin Kotschenreuther, David Stahl, Carola tho Pesch, Joanna Schiller, Franziska Byrtus, Dorothee Jochimsen, Viktoria Golumba-Nagy, David M. Kofler
Publikováno v:
Cells, Vol 11, Iss 14, p 2171 (2022)
Regulatory T (Treg) cells play an important role in immune tolerance and contribute to the prevention of autoimmune diseases, including rheumatoid arthritis (RA). The differentiation, function and stability of Treg cells is controlled by members of t
Externí odkaz:
https://doaj.org/article/5ebacef5e47e46d2b8a3982cf6fed0c8
Autor:
Nils Venhoff, Wolfgang A Schmidt, Raoul Bergner, Jürgen Rech, Leonore Unger, Hans-Peter Tony, Stephanie Finzel, Ioana Andreica, David M Kofler, Stefan M Weiner, Peter Lamprecht, Hendrik Schulze-Koops, Christine App, Effie Pournara, Meryl H Mendelson, Christian Sieder, Meron Maricos, Jens Thiel
Publikováno v:
The Lancet Rheumatology. 5:e341-e350
Autor:
Michaela Koehm, Tanja Rossmanith, Ann C Foldenauer, Eva Herrmann, Jan Brandt-Jürgens, Gerd R Burmester, Herbert Kellner, Uta Kiltz, David M Kofler, Jürgen Rech, Sorwe Mojtahed-Poor, Christin Jonetzko, Harald Burkhardt, Frank Behrens, Rieke H.E. Alten, Karolina Benesova, Raoul Bergner, Jürgen Braun, Winfried Demary, Stephanie Finzel, Peter Kästner, Arnd Kleye, Klaus Krüger, Gabriele Lorenz, Regina Max, Denis Poddubnyy, Andrea Rubbert-Roth, Holger Schwenke, Maren Sieburg, Diamant Thaci, Astrid Thiele, Reinhard E. Voll, Ulrich von Hinüber, Jochen Walter, Siegfried Wassenberg
Publikováno v:
The Lancet Rheumatology. 5:e14-e23
Autor:
Tina Schreiber, Lars Hagmeyer, David M. Kofler, Torsten Kubacki, Konrad Frank, Winfried J. Randerath
Publikováno v:
Pneumologie. 76:614-621
ZusammenfassungDie interstitielle Lungenerkrankung bedingt durch eine rheumatoide Arthritis (RA-ILD) hat eine hohe klinische Relevanz. Sie beeinflusst nicht nur die Lebensqualität, sondern hat auch einen erheblichen Anteil an der Mortalität der rhe
Autor:
David Stahl, David M. Kofler
Publikováno v:
Arthritis & Rheumatology.
Autor:
David Stahl, Carola tho Pesch, Carolin Brück, Ruth L Esser, Jan Thiele, Veronica Di Cristanziano, David M Kofler
Publikováno v:
RMD open. 8(2)
BackgroundSeveral health authorities recommend a third (booster) vaccination to protect patients with rheumatic and musculoskeletal diseases from severe COVID-19. Methotrexate has been shown to reduce the efficacy of the first and second dose of SARS