Zobrazeno 1 - 10
of 311
pro vyhledávání: '"David M. Koelle"'
Autor:
Kening Wang, Tristan Jordan, Kennichi Dowdell, Richard Herbert, Ian N. Moore, David M. Koelle, Jeffrey I. Cohen
Publikováno v:
PLoS Pathogens, Vol 20, Iss 9 (2024)
Externí odkaz:
https://doaj.org/article/d39e89f6ad864ca1906fffda1d57ae1f
Autor:
Michiel van Gent, Werner J. D. Ouwendijk, Victoria L. Campbell, Kerry J. Laing, Georges M. G. M. Verjans, David M. Koelle
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Trigeminal ganglia (TG) neurons are an important site of lifelong latent varicella-zoster virus (VZV) infection. Although VZV-specific T-cells are considered pivotal to control virus reactivation, their protective role at the site
Externí odkaz:
https://doaj.org/article/14716dfbf27c4c7298ae00f3d4233611
Autor:
Kerry J. Laing, Werner J. D. Ouwendijk, Victoria L. Campbell, Christopher L. McClurkan, Shahin Mortazavi, Michael Elder Waters, Maxwell P. Krist, Richard Tu, Nhi Nguyen, Krithi Basu, Congrong Miao, D. Scott Schmid, Christine Johnston, Georges M. G. M. Verjans, David M. Koelle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
T cells are considered important for controlling skin infections. Here, the authors report that varicella-zoster virus-specific T cells preferentially persist as tissue-resident-memory T cells in rash-involved skin after recovery from zoster.
Externí odkaz:
https://doaj.org/article/a1fabd9c8f51401c94e1954711560ae7
Autor:
Claire Buchta Rosean, Erica C. Leyder, Jeneice Hamilton, Joseph J. Carter, Denise A. Galloway, David M. Koelle, Paul Nghiem, Teri Heiland
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMost cases of Merkel cell carcinoma (MCC), a rare and highly aggressive type of neuroendocrine skin cancer, are associated with Merkel cell polyomavirus (MCPyV) infection. MCPyV integrates into the host genome, resulting in expression of
Externí odkaz:
https://doaj.org/article/6826851a63ae444b9426a08543e37702
Autor:
Anuradha Sooda, Francois Rwandamuriye, Celestine N. Wanjalla, Lichen Jing, David M. Koelle, Bjoern Peters, Shay Leary, Abha Chopra, Michael A. Calderwood, Simon A. Mallal, Rebecca Pavlos, Mark Watson, Elizabeth J. Phillips, Alec J. Redwood
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
HLA-B*57:01 restricted EBV-specific T-cell receptor specificity is altered by abacavir, suggesting a potentially inhibitory effect of abacavir on HLA-B*57:01 restricted TCR recognition.
Externí odkaz:
https://doaj.org/article/bcdd7ff4c80c420a8da2e27c19a3a258
Autor:
Charlotte A. James, Yuexin Xu, Melissa S. Aguilar, Lichen Jing, Erik D. Layton, Martine Gilleron, Adriaan J. Minnaard, Thomas J. Scriba, Cheryl L. Day, Edus H. Warren, David M. Koelle, Chetan Seshadri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
CD4 and CD8 co-receptors are routinely used to define distinct functional and phenotypic lineages of T cells. Here the authors show CD4 and CD8 also modulate the functional avidity of the CD1b-restricted response to mycobacterial lipid antigens
Externí odkaz:
https://doaj.org/article/5ffbba8ac40b4631bfdd4ca36548cb97
Autor:
Andres Chang, Anton M. Sholukh, Andreas Wieland, David L. Jaye, Mary Carrington, Meei-Li Huang, Hong Xie, Keith R. Jerome, Pavitra Roychoudhury, Alexander L. Greninger, Jean L. Koff, Jonathon B. Cohen, David M. Koelle, Lawrence Corey, Christopher R. Flowers, Rafi Ahmed
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 18 (2022)
Background Herpes simplex virus lymphadenitis (HSVL) is an unusual presentation of HSV reactivation in patients with chronic lymphocytic leukemia (CLL) and is characterized by systemic symptoms and no herpetic lesions. The immune responses during HSV
Externí odkaz:
https://doaj.org/article/b553259f84e34b31aaacb3c20315e95c
Autor:
Isabelle Q. Phan, Sandhya Subramanian, David Kim, Michael Murphy, Deleah Pettie, Lauren Carter, Ivan Anishchenko, Lynn K. Barrett, Justin Craig, Logan Tillery, Roger Shek, Whitney E. Harrington, David M. Koelle, Anna Wald, David Veesler, Neil King, Jim Boonyaratanakornkit, Nina Isoherranen, Alexander L. Greninger, Keith R. Jerome, Helen Chu, Bart Staker, Lance Stewart, Peter J. Myler, Wesley C. Van Voorhis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Rapid generation of diagnostics is paramount to understand epidemiology and to control the spread of emerging infectious diseases such as COVID-19. Computational methods to predict serodiagnostic epitopes that are specific for the pathogen c
Externí odkaz:
https://doaj.org/article/3d810cad4f2b46a1aaf7b89ba641e8bb
Autor:
Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Jim Boonyaratanakornkit, Anna Wald, Stacy Selke, Mark H. Wener, Chihiro Morishima, Alexander L. Greninger, Michael Gale Jr., Tien-Ying Hsiang, Lichen Jing, Michael R. Holbrook, Ian M. Kaplan, H. Jabran Zahid, Damon H. May, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S. Robins, David M. Koelle
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
BACKGROUND Measuring the immune response to SARS-CoV-2 enables assessment of past infection and protective immunity. SARS-CoV-2 infection induces humoral and T cell responses, but these responses vary with disease severity and individual characterist
Externí odkaz:
https://doaj.org/article/c720e1a7f2ea4a9bb6e8db6d06e7b8ab
Autor:
Lichen Jing, Xia Wu, Maxwell P. Krist, Tien-Ying Hsiang, Victoria L. Campbell, Christopher L. McClurkan, Sydney M. Favors, Lawrence A. Hemingway, Charmie Godornes, Denise Q. Tong, Stacy Selke, Angela C. LeClair, Chu-Woo Pyo, Daniel E. Geraghty, Kerry J. Laing, Anna Wald, Michael Gale Jr., David M. Koelle
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
SARS-CoV-2 provokes a robust T cell response. Peptide-based studies exclude antigen processing and presentation biology, which may influence T cell detection studies. To focus on responses to whole virus and complex antigens, we used intact SARS-CoV-
Externí odkaz:
https://doaj.org/article/ac5bab028d2c47d8a3ac6df92bba3c0e