Zobrazeno 1 - 10
of 215
pro vyhledávání: '"David M. Kern"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionResults of retrospective studies examining the relationship between prolactin increasing antipsychotics and incident breast cancer have been inconsistent. This study assessed the association between use of high prolactin increasing antips
Externí odkaz:
https://doaj.org/article/4c599318a5be4181aa9cf067055979e8
Autor:
Yi Chai, Kenneth K. C. Man, Hao Luo, Carmen Olga Torre, Yun Kwok Wing, Joseph F. Hayes, David P. J. Osborn, Wing Chung Chang, Xiaoyu Lin, Can Yin, Esther W. Chan, Ivan C. H. Lam, Stephen Fortin, David M. Kern, Dong Yun Lee, Rae Woong Park, Jae-Won Jang, Jing Li, Sarah Seager, Wallis C. Y. Lau, Ian C. K. Wong
Publikováno v:
Epidemiology and Psychiatric Sciences, Vol 33 (2024)
Abstract Aims Population-wide restrictions during the COVID-19 pandemic may create barriers to mental health diagnosis. This study aims to examine changes in the number of incident cases and the incidence rates of mental health diagnoses during the C
Externí odkaz:
https://doaj.org/article/06d9737b96e4437897447ac610afa4aa
Publikováno v:
Epilepsia Open, Vol 7, Iss 4, Pp 598-607 (2022)
Abstract Objective The prevalence of epilepsy is slightly higher in women than in men and sensitivity to seizure stimuli differs between sexes. Some evidence suggests sex differences in response to antiseizure medications exist mainly due to inconsis
Externí odkaz:
https://doaj.org/article/f6a6afd43ffd4a5ba42b2834f1bb71b7
Autor:
David M. Kern, Carla M. Canuso, Ella Daly, Jonathan C. Johnson, Dong Jing Fu, Teodora Doherty, Cori Blauer‐Peterson, M. Soledad Cepeda
Publikováno v:
Brain and Behavior, Vol 13, Iss 8, Pp n/a-n/a (2023)
Abstract Background The impact of treatment‐resistant depression (TRD) or prior suicidal ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major depressive disorder (MDD) is not well known. This retrospective, observation
Externí odkaz:
https://doaj.org/article/ee48d3f794b64e1da90c9a8a22676717
Autor:
David M. Kern, Rachel E. Teneralli, Christopher M. Flores, Gayle M. Wittenberg, James P. Gilbert, M. Soledad Cepeda
Publikováno v:
Psychiatric Research and Clinical Practice, Vol 4, Iss 1, Pp 12-20 (2022)
Objective To systematically identify novel pharmacological strategies for preventing or treating post‐traumatic stress disorder (PTSD) by leveraging large‐scale analysis of real‐world observational data. Methods Using a self‐controlled study
Externí odkaz:
https://doaj.org/article/bd6ca9d67bf74e66a848765def5716e3
Autor:
Susheel K. Gunasekar, Litao Xie, Ashutosh Kumar, Juan Hong, Pratik R. Chheda, Chen Kang, David M. Kern, Chau My-Ta, Joshua Maurer, John Heebink, Eva E. Gerber, Wojciech J. Grzesik, Macaulay Elliot-Hudson, Yanhui Zhang, Phillip Key, Chaitanya A. Kulkarni, Joseph W. Beals, Gordon I. Smith, Isaac Samuel, Jessica K. Smith, Peter Nau, Yumi Imai, Ryan D. Sheldon, Eric B. Taylor, Daniel J. Lerner, Andrew W. Norris, Samuel Klein, Stephen G. Brohawn, Robert Kerns, Rajan Sah
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-25 (2022)
Type 2 diabetes is associated with insulin resistance, impaired insulin secretion and liver steatosis. Here the authors report a proof-of-concept study for small molecule SWELL1 modulators as a therapeutic approach to treat diabetes and associated li
Externí odkaz:
https://doaj.org/article/f4d1fee19c624c0a9f1b40ef56f78e04
Autor:
Yiting Wang, Laura L. Hester, Jennifer Lofland, Shawn Rose, Chetan S. Karyekar, David M. Kern, Margaret Blacketer, Kourtney Davis, Kimberly Shields-Tuttle
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-6 (2022)
Abstract Objective To provide current estimates of the number of patients with prevalent systemic lupus erythematosus (SLE) by major health insurance types in the US and to describe patient characteristics. Four large US health insurance claims datab
Externí odkaz:
https://doaj.org/article/4f3f3ff6bc46415793a20559ff76f219
Publikováno v:
BMC Psychiatry, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background There is a knowledge gap regarding the treatment patterns of patients with major depressive disorder (MDD) who experience suicidal ideation or a suicide attempt (SI/SA). Methods Patients with SI/SA were identified from a large US-
Externí odkaz:
https://doaj.org/article/edb39b9d3c874f6fa91e5d990465357d
Autor:
Kimberly A Dolan, Mandira Dutta, David M Kern, Abhay Kotecha, Gregory A Voth, Stephen G Brohawn
Publikováno v:
eLife, Vol 11 (2022)
SARS-CoV-2 encodes four structural proteins incorporated into virions, spike (S), envelope (E), nucleocapsid (N), and membrane (M). M plays an essential role in viral assembly by organizing other structural proteins through physical interactions and
Externí odkaz:
https://doaj.org/article/e30b73ef0ebc4151b16b3ceff1fe0988
Autor:
David M. Kern, M. Soledad Cepeda
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background The treatment landscape for multiple sclerosis (MS) is quickly evolving. Understanding real-world treatment patterns of patients is necessary to identifying potential gaps in care. Methods Patients with incident MS were identified
Externí odkaz:
https://doaj.org/article/e03df307c2c546928cf226572fccfceb