Zobrazeno 1 - 10
of 35
pro vyhledávání: '"David M. Kelso"'
Autor:
Matthew A. Butzler, Mário F. Neto, David M. Kelso, Jennifer L. Reed, Xiang Rui, Mark James Fisher, Sally M. McFall
Publikováno v:
Journal of Virological Methods. 248:107-115
The lack of hepatitis C virus (HCV) diagnostic tests designed for use in decentralized settings is a major obstacle for providing access to treatment and prevention services particularly in low and middle income countries. Here we describe the develo
Autor:
Debby Basu, Mark P. Nicol, Jennifer L. Reed, David M. Kelso, Sally M. McFall, Zachary J. Walker, Veronica Allen
Publikováno v:
Tuberculosis. 101:114-124
SummaryNucleic acid amplification tests for Mycobacterium tuberculosis (MTB) detection from sputum are highly sensitive and specific with smear microscopy positive specimens, but their sensitivity with smear-negative/culture-positive specimens is muc
Autor:
Sally M. McFall, Sujit Jangam, Robin L. Wagner, Diana Hardie, David M. Kelso, Douglas H. Yamada
Publikováno v:
Journal of Virological Methods. 214:37-42
Early diagnosis and access to treatment for infants with human immunodeficiency virus-1 (HIV-1) is critical to reduce infant mortality. The lack of simple point-of-care tests impedes the timely initiation of antiretroviral therapy. The development of
Autor:
David M. Kelso, Roger Ekins
Publikováno v:
Clinical Chemistry. 57:372-375
The need for assay methods of sufficient sensitivity to determine the low concentrations of hormones present in body fluids led to the original development of immunoassays and analogous “binding” (or “ligand”) assays in the late 1950s and ear
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 55:413-419
Currently, the majority of HIV-infected infants are found within limited-resource settings, where inadequate screening for HIV due to the lack of access to simple and affordable point-of-care tests impedes implementation of antiretroviral therapy. He
Multispectral image analysis of binary encoded microspheres for highly multiplexed suspension arrays
Autor:
David M. Kelso, Abhishek Mathur
Publikováno v:
Cytometry Part A. :356-365
To push the 100-plex envelope of suspension array technology, we have developed fully automated methods to acquire multi-spectral images of multiplexed quantum-dot (QD) encoded microspheres, to segment them in the images, to classify them based on th
Publikováno v:
Journal of Clinical Microbiology. 47:2363-2368
PCR detection of human immunodeficiency virus type 1 (HIV-1) proviral DNA is the method recommended for use for the diagnosis of HIV-1 infection in infants in limited-resource settings. Currently, testing must be performed in central laboratories, wh
Autor:
Matilda Nduna, Tyler Joseph Maiers, Sally M. McFall, Kara M. Palamountain, Wendy S. Stevens, David M. Kelso, Mark James Fisher, Natasha Gous, Lesley Scott
Publikováno v:
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 105(3)
Background: Viral load (VL) quantification is an important tool in determining newly developed drug resistance or problems with adherence to antiretroviral therapy (ART) in HIV-positive patients. VL monitoring is becoming the standard of care in many
Publikováno v:
Annals of Allergy, Asthma & Immunology. 116:475-476
Publikováno v:
Analytical Chemistry. 75:1147-1154
An automated imaging system was developed to quantify fluorescence signals from particles immobilized on hydrogel-coated slides. Arrays of submicrometer-diameter particles were printed with up to 600 particles/spot. The slides were read under 20x mag