Zobrazeno 1 - 10 of 150 pro vyhledávání: '"David M. Jackman"'
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Data from Autocrine Production of Amphiregulin Predicts Sensitivity to Both Gefitinib and Cetuximab in EGFR Wild-type Cancers
Autor: Pasi A. Jänne, Bruce E. Johnson, Andrew M. Rogers, Feng Zhao, David M. Jackman, Alison J. Homes, Neal Lindeman, Kreshnik Zejnullahu, Kimio Yonesaka
Purpose: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors, gefitinib and erlotinib, lead to significant tumor regressions in 10% to 15% of non-small cell lung cancer (NSCLC) patients with EGFR activating mutations. However, 30% to 4
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084c4ec565e0e763a3396a75b07064fc
https://doi.org/10.1158/1078-0432.c.6516916.v1
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Supplemental Figure 2 from Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma
Autor: Pasi A. Jänne, David M. Jackman, Geoffrey R. Oxnard, Suzanne E. Dahlberg, Christine Lydon, Mohit Butaney, Jason L. Hornick, Ashley K. Pelton, Scott J. Rodig, Lynette M. Sholl, Antonio Calles
Supplemental Figure 2. A, KRAS G12C mutation is the most frequently mutated in smokers while G12D is most common in never-smokers. B and C, Never-smokers were significantly more likely than former or current smokers to have a transition mutation (G>A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e3f79c852edc3b4f79ef8a65b92632
https://doi.org/10.1158/1078-0432.22461309
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Plný text Recenzováno Digitální knihovna AV ČR
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