Zobrazeno 1 - 6
of 6
pro vyhledávání: '"David M. J. Duhl"'
Publikováno v:
Genetics. 144:265-277
The mouse agouti protein is a paracrine signaling molecule that causes yellow pigment synthesis. A pale ventral coloration distinguishes the light-bellied agouti (AW) from the agouti (A) allele, and is caused by expression of ventral-specific mRNA is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23cd4a80579ba933d6f2bb9eecb04146
https://doi.org/10.1093/genetics/144.1.265
https://doi.org/10.1093/genetics/144.1.265
Publikováno v:
Proceedings of the National Academy of Sciences. 91:5667-5671
The agouti coat color gene encodes a paracrine signaling molecule that controls the production of yellow and black pigment by melanocytes within hair follicles. Some agouti alleles affect the dorsum and ventrum independently, which has provided the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1561d59f78d31331dfa6fa55bfe415c2
https://doi.org/10.1073/pnas.91.12.5667
https://doi.org/10.1073/pnas.91.12.5667
Autor:
Mary E. Stevens, M. W. Miller, P. J. Saxon, Gregory S. Barsh, David M. J. Duhl, C. J. Epstein, Harry Vrieling
Publikováno v:
Development. 120:1695-1708
Heterozygosity for the mouse lethal yellow(Ay) mutation leads to obesity, increased tumor susceptibility and increased activity of the agouti coat color gene; homozygosity for Ay results in embryonic death around the time of implantation. Although th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0856a8f5faa53f9413b19c4d242c5b
https://doi.org/10.1242/dev.120.6.1695
https://doi.org/10.1242/dev.120.6.1695
Autor:
M. W. Miller, B. M. Winkes, F. Arredondo-Vega, P. J. Saxon, Gregory S. Barsh, C. J. Epstein, David M. J. Duhl, Michael S. Hershfield, G. L. Wolff
Publikováno v:
The EMBO Journal. 13:1806-1816
The lethal nonagouti (a(x)) mutation is a hypomorphic allele of the agouti coat color locus which, when homozygous, also leads to embryonic death around the time of implantation. To understand the molecular basis of these phenotypes, we identified an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1893583c26ef1d8d3348f02bd56bb86
https://doi.org/10.1002/j.1460-2075.1994.tb06449.x
https://doi.org/10.1002/j.1460-2075.1994.tb06449.x
Autor:
M. W. Miller, B. M. Winkes, David M. J. Duhl, Harry Vrieling, Gregory S. Barsh, Sabine P. Cordes, Michael Martin Ollmann
Publikováno v:
Genes & Development. 7:454-467
The mouse agouti gene controls the deposition of yellow and black pigment in developing hairs. Several dominant alleles, including lethal yellow (Ay), result in the exclusive production of yellow pigment and have pleiotropic effects that include obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641c57cf8941157d503d4000b0db454a
https://doi.org/10.1101/gad.7.3.454
https://doi.org/10.1101/gad.7.3.454
Publikováno v:
Nature genetics. 8(1)
Several dominant mutations of the mouse agouti coat colour gene have pleiotropic effects that include obesity and a yellow coat. The Ay allele is caused by a large deletion that affects the expression of several contiguous genes. We show that three o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c0e9894c7f90c4710795c5eb9a25c0
https://pubmed.ncbi.nlm.nih.gov/7987393
https://pubmed.ncbi.nlm.nih.gov/7987393