Zobrazeno 1 - 10
of 27
pro vyhledávání: '"David M. Hoover"'
Autor:
Girma Woldehawariat, Pedro E Martinez, Peter Hauser, David M Hoover, Wayne W C Drevets, Francis J McMahon
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99980 (2014)
Anatomical differences in the corpus callosum have been found in various psychiatric disorders, but data on the genetic contributions to these differences have been limited. The current study used morphometric MRI data to assess the heritability of c
Externí odkaz:
https://doaj.org/article/5d55462c3eb042b7a010b43508f2fcfc
Autor:
Martha L. Ludwig, David M. Hoover
Publikováno v:
Protein Science. 6:2525-2537
In Escherichia coli, flavodoxin is the physiological electron donor for the reductive activation of the enzymes pyruvate formate-lyase, anaerobic ribonucleotide reductase, and B12-dependent methionine synthase. As a basis for studies of the interacti
Publikováno v:
Journal of Biological Chemistry. 282:1819-1829
Defensins are small (30-45 amino acid residues) cationic proteins with broad antimicrobial activity against many bacteria and fungi, some enveloped viruses, and other activities such as chemoattraction of a range of different cell types to the sites
Publikováno v:
Annual Review of Immunology. 22:181-215
Mammals generate a diverse array of antimicrobial proteins, largely represented by defensins or cathelicidins. The direct in vitro microbicidal activity of antimicrobial proteins has long been considered an important innate immune defense, although t
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 59:1165-1173
Thymus and activation-regulated chemokine (TARC) is a CC chemokine that is mainly expressed in the thymus. TARC interacts primarily with the CCR4 receptor and to a lesser extent with the CCR8 receptor. The structures of TARC have been solved by molec
Autor:
David M. Hoover, De Yang, Joost J. Oppenheim, Cyril Boulègue, Wuyuan Lu, Jacek Lubkowski, Kenneth D. Tucker
Publikováno v:
Journal of Biological Chemistry. 277:37647-37654
Human macrophage inflammatory protein-3alpha (MIP-3alpha; CCL20) is a CC-type chemokine that binds to and activates CC chemokine receptor-6 (CCR6). Although MIP-3alpha does not share the binding site of CCR6 with any other chemokine, human beta-defen
Publikováno v:
Journal of Biological Chemistry. 276:39021-39026
Defensins are a class of small cationic peptides found in higher organisms that serve as both antimicrobial and cell signaling molecules. The exact mechanism of the antimicrobial activity of defensins is not known, but two models have been postulated
Autor:
Anita L. Metzger, Christian Weber, Catherine L. Drennan, Katherine A. Pattridge, David M. Hoover, Martha L. Ludwig
Publikováno v:
Journal of Molecular Biology. 294:711-724
Flavodoxin from Anacystis nidulans ( Synechococcus PCC 7942) was the first member of the flavodoxin family to be characterized, and is the structural prototype for the “long-chain” flavodoxins that have molecular masses of ∼20 kDa. Crystal stru
Autor:
Catherine L. Drennan, Martha L. Ludwig, Christian Weber, Anita L. Metzger, David M. Hoover, Charles Osborne, Katherine A. Pattridge
Publikováno v:
Journal of Molecular Biology. 294:725-743
The long-chain flavodoxins, with 169-176 residues, display oxidation-reduction potentials at pH 7 that vary from -50 to -260 mV for the oxidized/semiquinone (ox/sq) equilibrium and are -400 mV or lower for the semiquinone/hydroquinone (sq/hq) equilib
Autor:
Satish Menon, Alexander Wlodawer, Céline Schalk-Hihi, Chuan-Chu Chou, Alexander Zdanov, David M. Hoover
Publikováno v:
European Journal of Biochemistry. 262:134-141
Interleukin-10 (IL-10) is a pleiotropic immunosuppressive cytokine that has a wide range of effects in controlling inflammatory responses. Viral IL-10 (vIL-10) is a homologue of human IL-10 (hIL-10) produced by Epstein-Barr virus (EBV). Both hIL-10 a