Zobrazeno 1 - 10
of 185
pro vyhledávání: '"David M. Ho"'
Autor:
Filip Ottosson, Francesco Russo, Anna Abrahamsson, Nadia MacSween, Julie Courraud, Kristin Skogstrand, Olle Melander, Ulrika Ericson, Marju Orho-Melander, Arieh S. Cohen, Jakob Grove, Preben Bo Mortensen, David M. Hougaard, Madeleine Ernst
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background The prevalence of autism in Denmark has been increasing, reaching 1.65% among 10-year-old children, and similar trends are seen elsewhere. Although there are several factors associated with autism, including genetic, environmental
Externí odkaz:
https://doaj.org/article/c2ef8d3921514b3ea5ecafec64670785
Autor:
Maria Victoria Fernandez, Menghan Liu, Aleksandra Beric, Matt Johnson, Arda Cetin, Maulik Patel, John Budde, Pat Kohlfeld, Kristy Bergmann, Joseph Lowery, Allison Flynn, William Brock, Brenda Sanchez Montejo, Jen Gentsch, Nicholas Sykora, Joanne Norton, Olga Valdez, Priyanka Gorijala, Jessie Sanford, Yichen Sun, Ciyang Wang, Dan Western, Jigyasha Timsina, Tassia Mangetti Goncalves, Anh N. Do, Yun Ju Sung, Guoyan Zhao, John C. Morris, Krista Moulder, David M. Holtzman, Randall J. Bateman, Celeste Karch, Jason Hassenstab, Chengjie Xiong, Suzanne E. Schindler, Joyce (Joy) Balls-Berry, Tammie L. S. Benzinger, Richard J. Perrin, Andrea Denny, B. Joy Snider, Susan L. Stark, Laura Ibanez, Carlos Cruchaga
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-19 (2024)
Abstract The Knight-Alzheimer Disease Research Center (Knight-ADRC) at Washington University in St. Louis has pioneered and led worldwide seminal studies that have expanded our clinical, social, pathological, and molecular understanding of Alzheimer
Externí odkaz:
https://doaj.org/article/1469c9617a64436fbff15b0d11b166cb
Autor:
Chengjie Xiong, Jingqin Luo, David A. Wolk, Leslie M. Shaw, Erik D. Roberson, Charles F. Murchison, Rachel L. Henson, Tammie L. S. Benzinger, Quoc Bui, Folasade Agboola, Elizabeth Grant, Emily N. Gremminger, Krista L. Moulder, David S. Geldmacher, Olivio J. Clay, Ganesh Babulal, Carlos Cruchaga, David M. Holtzman, Randall J. Bateman, John C. Morris, Suzanne E. Schindler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Blood-based biomarkers of Alzheimer disease (AD) may facilitate testing of historically under-represented groups. The Study of Race to Understand Alzheimer Biomarkers (SORTOUT-AB) is a multi-center longitudinal study to compare AD biomarkers
Externí odkaz:
https://doaj.org/article/7e17f1f8091f4e35b67e41ede981da17
Autor:
L. David Carter, Donna Christensen, David M. Hopkins, John V. Matthews, Robert E. Nelson, Lynn E. Ovenden, Natalia Rybczynski, Tamara L. Fletcher
Publikováno v:
Arctic, Antarctic, and Alpine Research, Vol 56, Iss 1 (2024)
Motivated by the need for more paleodata for Pliocene paleoclimate data-model comparison, we revisited unpublished investigations of a fossiliferous site on the Niguanak River in Arctic North America. Analyses of the samples indicates forested condit
Externí odkaz:
https://doaj.org/article/29317c716f5848ca956364b559a70c96
Autor:
Joeri Meijsen, Kejia Hu, Morten D. Krebs, Georgios Athanasiadis, Sarah Washbrook, Richard Zetterberg, Raquel Nogueira Avelar e Silva, John R. Shorter, Jesper R. Gådin, Jacob Bergstedt, David M. Howard, Weimin Ye, Yi Lu, Unnur A. Valdimarsdóttir, Andrés Ingason, Dorte Helenius, Oleguer Plana-Ripoll, John J. McGrath, Nadia Micali, Ole A. Andreassen, Thomas M. Werge, Fang Fang, Alfonso Buil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Mental disorders are leading causes of disability and premature death worldwide, partly due to high comorbidity with cardiometabolic disorders. Reasons for this comorbidity are still poorly understood. We leverage nation-wide health records
Externí odkaz:
https://doaj.org/article/b590855b0172469c974a0c55e5a42e1d
Autor:
Zengjie Xia, Emily E. Prescott, Agnieszka Urbanek, Hollie E. Wareing, Marianne C. King, Anna Olerinyova, Helen Dakin, Tom Leah, Katy A. Barnes, Martyna M. Matuszyk, Eleni Dimou, Eric Hidari, Yu P. Zhang, Jeff Y. L. Lam, John S. H. Danial, Michael R. Strickland, Hong Jiang, Peter Thornton, Damian C. Crowther, Sohvi Ohtonen, Mireia Gómez-Budia, Simon M. Bell, Laura Ferraiuolo, Heather Mortiboys, Adrian Higginbottom, Stephen B. Wharton, David M. Holtzman, Tarja Malm, Rohan T. Ranasinghe, David Klenerman, Suman De
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Which isoforms of apolipoprotein E (apoE) we inherit determine our risk of developing late-onset Alzheimer’s Disease (AD), but the mechanism underlying this link is poorly understood. In particular, the relevance of direct interactions bet
Externí odkaz:
https://doaj.org/article/65a320a335c64d1798e94a4de6e507f4
Autor:
Megan E. Bosch, Hemraj B. Dodiya, Julia Michalkiewicz, Choonghee Lee, Shabana M. Shaik, Ian Q. Weigle, Can Zhang, Jack Osborn, Aishwarya Nambiar, Priyam Patel, Samira Parhizkar, Xiaoqiong Zhang, Marie L. Laury, Prasenjit Mondal, Ashley Gomm, Matthew John Schipma, Dania Mallah, Oleg Butovsky, Eugene B. Chang, Rudolph E. Tanzi, Jack A. Gilbert, David M. Holtzman, Sangram S. Sisodia
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/14d8b48203894334ae62b75a08c5835b
Autor:
Jeremy L. Pinyon, Georg vonJonquieres, Edward N. Crawford, Amr Al Abed, John M. Power, Matthias Klugmann, Cherylea J. Browne, David M. Housley, Andrew K. Wise, James B. Fallon, Robert K. Shepherd, John Y. Lin, Catherine McMahon, David McAlpine, Catherine S. Birman, Waikong Lai, Ya Lang Enke, Paul M. Carter, James F. Patrick, Robert D. Gay, Corinne Marie, Daniel Scherman, Nigel H. Lovell, Gary D. Housley
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Viral vectors and lipofection‐based gene therapies have dispersion‐dependent transduction/transfection profiles that thwart precise targeting. The study describes the development of focused close‐field gene electrotransfer (GET) techno
Externí odkaz:
https://doaj.org/article/1f120ece41dd42df991a8e5de27489c2
Autor:
Kenneth I. Aycock, Tom Battisti, Ashley Peterson, Jiang Yao, Steven Kreuzer, Claudio Capelli, Sanjay Pant, Pras Pathmanathan, David M. Hoganson, Steve M. Levine, Brent A. Craven
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Computational models of patients and medical devices can be combined to perform an in silico clinical trial (ISCT) to investigate questions related to device safety and/or effectiveness across the total product life cycle. ISCTs can potentially accel
Externí odkaz:
https://doaj.org/article/ccb778af6883417ab746f816059b55be
Autor:
David M. Hoganson, MD, Vijay Govindarajan, PhD, Noah E. Schulz, MS, Emily R. Eickhoff, MS, Roger E. Breitbart, MD, Gerald R. Marx, MD, Pedro J. del Nido, MD, Peter E. Hammer, PhD
Publikováno v:
JACC: Advances, Vol 3, Iss 7, Pp 101057- (2024)
Background: Single ventricle (SV) patients with interrupted inferior vena cava (iIVC) and azygos continuation are at high risk for unbalanced hepatic venous flow (HVF) distribution to the lungs after Fontan completion and subsequent pulmonary arterio
Externí odkaz:
https://doaj.org/article/84a69bdb279e4fadb03794f070dcf3a3