Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David M. Hedges"'
Autor:
David M. Hedges, John C. Hegman, Jefferson R. Brown, Jack T. Wilburn, Brian E. Chapman, Christopher R. Butson
Publikováno v:
Frontiers in Neuroinformatics, Vol 14 (2020)
BackgroundNeuromodulation therapies, such as deep brain stimulation (DBS), spinal cord stimulation (SCS), responsive neurostimulation (RNS), transcranial magnetic stimulation (TMS), transcranial direct stimulation (tDCS), and vagus nerve stimulation
Externí odkaz:
https://doaj.org/article/39cc6ad813b34795b88e6cfef9220c53
Autor:
David M. Hedges, Jordan T. Yorgason, Andrew W. Perez, Nathan D. Schilaty, Benjamin M. Williams, Richard K. Watt, Scott C. Steffensen
Publikováno v:
Antioxidants, Vol 9, Iss 12, p 1285 (2020)
Parkinson’s disease is associated with degeneration of neuromelanin (NM)-containing substantia nigra dopamine (DA) neurons and subsequent decreases in striatal DA transmission. Dopamine spontaneously forms a melanin through a process called melanog
Externí odkaz:
https://doaj.org/article/ae3bf70cd6c443d7a7babb84b59ce6c0
Autor:
Scott C. Steffensen, Mark Woodbury, David M. Hedges, Marilou A. Andres, Kyle B. Bills, Eun Young Jang, Ben Williams, Mandy J Parsons, J Daniel Obray, Jordan T. Yorgason
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Methamphetamine (METH) enhances exocytotic dopamine (DA) signals and induces DA transporter (DAT) mediated efflux in brain striatal regions such as the nucleus accumbens (NAc). Blocking sigma receptors prevents METH-induced DA increases. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc4aa8ad129b11334f39659855c0ba7
https://doi.org/10.1007/s00213-020-05459-2
https://doi.org/10.1007/s00213-020-05459-2
Autor:
David M. Hansen, Alyssa L. Stockard, Scott C. Steffensen, Eun Young Jang, Anna M. Lee, James N. Brundage, Nathan D. Schilaty, Elizabeth J. Anderson, Martin Wallner, David M. Hedges, Hillary A. Wadsworth, Stephen T. Jones, Benjamin M. Williams, Summer B. Arthur, Jordan T. Yorgason
Publikováno v:
Addict Biol
Previous studies indicate that moderate-to-high ethanol (EtOH) concentrations enhance dopamine (DA) neurotransmission in the mesolimbic DA system from the ventral tegmental area (VTA) and projecting to the nucleus accumbens core (NAc). However, volta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b34453712ee97c23190f6d57438374
https://doi.org/10.1111/adb.13108
https://doi.org/10.1111/adb.13108
Autor:
David M. Hedges, William B. Kiosses, Amanda J. Roberts, Roman Vlkolinsky, Florence P. Varodayan, Reesha R. Patel, Marisa Roberto, Michal Bajo, Tali Nadav, Michael Q. Steinman, Sophia Khom, Ilham Polis
Publikováno v:
Brain, Behavior, and Immunity. 75:208-219
The interleukin-1 system (IL-1) is a prominent pro-inflammatory pathway responsible for the initiation and regulation of immune responses. Human genetic and preclinical studies suggest a critical role for IL-1β signaling in ethanol drinking and depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97618181382a91f359d7b4bc3facbd9
https://doi.org/10.1016/j.bbi.2018.10.009
https://doi.org/10.1016/j.bbi.2018.10.009
Autor:
Dean Kirson, David M. Hedges, Florence P. Varodayan, Sarah A. Wolfe, Sophia Khom, Marisa Roberto, Reesha R. Patel, Michal Bajo
Publikováno v:
J Neurosci
Excessive serotonin (5-HT) signaling plays a critical role in the etiology of alcohol use disorder. The central nucleus of the amygdala (CeA) is a key player in alcohol-dependence associated behaviors. The CeA receives dense innervation from the dors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d25513065c92791bf7884c45b2e568c
https://pubmed.ncbi.nlm.nih.gov/32769108
https://pubmed.ncbi.nlm.nih.gov/32769108
Autor:
David M. Hedges, John C. Hegman, Jefferson R. Brown, Jack T. Wilburn, Brian E. Chapman, Christopher R. Butson
Publikováno v:
Frontiers in Neuroinformatics
Frontiers in Neuroinformatics, Vol 14 (2020)
Frontiers in Neuroinformatics, Vol 14 (2020)
Background Neuromodulation therapies, such as deep brain stimulation (DBS), spinal cord stimulation (SCS), responsive neurostimulation (RNS), transcranial magnetic stimulation (TMS), transcranial direct stimulation (tDCS), and vagus nerve stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70af955b2debe569afffa4ed26aa3871
https://pubmed.ncbi.nlm.nih.gov/33071769
https://pubmed.ncbi.nlm.nih.gov/33071769
Autor:
Henrique Ballalai Ferraz, David M. Hedges, Gordon Duffley, Lauren E. Schrock, Johannes Vorwerk, Camila C. Aquino, Christopher R. Butson, Paul A. House, John D. Rolston
Publikováno v:
Movement disorders : official journal of the Movement Disorder SocietyReferences. 34(11)
BACKGROUND In patients with Parkinson's disease, stimulation above the subthalamic nucleus (STN) may engage the pallidofugal fibers and directly suppress dyskinesia. OBJECTIVES The objective of this study was to evaluate the effect of interleaving st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad96c7aa71fefc46fa043eba977926a4
https://pubmed.ncbi.nlm.nih.gov/31483534
https://pubmed.ncbi.nlm.nih.gov/31483534
Autor:
Eun Young Jang, Soo Phil Kim, Scott C. Steffensen, Tyler G. Ekins, Brandon T. Garcia, David M. Hedges, Ashley C. Nelson, Hee Young Kim, Jun Yeon Lee, Nam Jun Kim, Chae Ha Yang
Publikováno v:
Addiction Biology. 22:1304-1315
Methamphetamine (METH) markedly increases dopamine (DA) release in the mesolimbic DA system, which plays an important role in mediating the reinforcing effects of METH. METH-induced DA release results in the formation of reactive oxygen species (ROS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fa61892a920fa8957a84d23ed83aca8
https://doi.org/10.1111/adb.12419
https://doi.org/10.1111/adb.12419
Autor:
David M. Hedges, Tony D. Davis, Marisa Roberto, Reesha R. Patel, Yuri A. Blednov, Michael D. Burkart, Michal Bajo, Roman Vlkolinsky, Florence P. Varodayan
Publikováno v:
Brain Sciences
Volume 9
Issue 12
Volume 9
Issue 12
Myeloid differentiation primary response protein (MyD88) is a critical neuroimmune adaptor protein in TLR (Toll-like receptor) and IL-1R (Interleukin-1 receptor) signaling complexes. These two pro-inflammatory families play an important role in the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e9160fec2b0c0f148812375fb992ae
https://doi.org/10.3390/brainsci9120361
https://doi.org/10.3390/brainsci9120361