Zobrazeno 1 - 10
of 213
pro vyhledávání: '"David M. Guidot"'
Autor:
Benyam P. Yoseph, Elise Breed, Christian E. Overgaard, Christina J. Ward, Zhe Liang, Maylene E. Wagener, Daniel R. Lexcen, Elizabeth R. Lusczek, Greg J. Beilman, Eileen M. Burd, Alton B. Farris, David M. Guidot, Michael Koval, Mandy L. Ford, Craig M. Coopersmith
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
Externí odkaz:
https://doaj.org/article/5fe87ad187354094a43e42780e6cc4ce
Autor:
Barbara Schlingmann, Christian E. Overgaard, Samuel A. Molina, K. Sabrina Lynn, Leslie A. Mitchell, StevenClaude Dorsainvil White, Alexa L. Mattheyses, David M. Guidot, Christopher T. Capaldo, Michael Koval
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Alcohol abuse is a risk factor for acute respiratory distress syndrome, flooding of the lungs due to compromised barrier function. Here the authors report that alcohol upregulates claudin-5 that is then recruited to tight junctions in alveolar epithe
Externí odkaz:
https://doaj.org/article/a496d44daea84ffd8ac69b4def97a4bf
Autor:
Deena B. Chihade, Prestina Smith, David A. Swift, Shunsuke Otani, Wenxiao Zhang, Ching-Wen Chen, Lauren A. Jeffers, Zhe Liang, Takashi Shimazui, Eileen M. Burd, Alton B. Farris, Bashar S. Staitieh, David M. Guidot, Mandy L. Ford, Michael Koval, Craig M. Coopersmith
Publikováno v:
Shock. 59:612-620
Autor:
Gregory W. Wigger, Darya Khani, Mariam Ahmed, Layal Sayegh, Sara C. Auld, Xian Fan, David M. Guidot, Bashar S. Staitieh
Publikováno v:
Alcoholism: Clinical and Experimental Research. 46:2214-2224
Alcohol impairs pulmonary innate immune function and is associated with an increased risk of tuberculosis (TB). Toll-like receptor 2 (TLR2) is a pattern recognition receptor on alveolar macrophages that recognizes Mycobacterium tuberculosis (Mtb). Th
Publikováno v:
Am J Med Sci
Background Despite anti-retroviral therapy, HIV-1 infection increases the risk of pneumonia and causes oxidative stress and defective alveolar macrophage (AM) immune function. We have previously determined that HIV-1 proteins inhibit antioxidant defe
Autor:
David M. Guidot
Publikováno v:
The American journal of the medical sciences. 362(6)
Therefore, we inevitably increase tidal volume, driving pressure, and MP in individuals with the most severe lung injury such that these parameters may be associated with, but not causal to, the outcomes in acute lung injury. However, I remember all
Autor:
Bashar S. Staitieh, Brooks M. Hybertson, Xian Fan, Bifeng Gao, Joe M. McCord, David M. Guidot, Abiodun T. Kukoyi
Publikováno v:
Am J Physiol Cell Physiol
Chronic HIV infection causes redox stress and increases the risk of acute and chronic lung injury, even when individuals are adherent to antiretroviral therapy. HIV-1 transgene expression in rats inhibits nuclear factor (erythroid-derived 2)-like 2 (
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Alcohol exposure induces TGFβ1 and renders the lung susceptible to injury and disrepair. We determined that TGFβ1 regulates myofibroblast differentiation through the loss of Thy-1 expression and consequent induction of α-SMA. TGFβ1 is
Publikováno v:
TP95. TP095 TUBERCULOSIS CLINICAL AND BASIC STUDIES.
Autor:
Deborah Molehin, Bum-Yong Kang, Justin M. Smith, Sonia C. Flores, Laurence Huang, Roy L. Sutliff, Cari F. Kessing, Kevin Pruitt, Edgar G. Martinez, Edu B Suárez-Martínez, Bryan McNair, Kaiser M. Bijli, Sushma K. Cribbs, Laura Pumarejo-Gomez, Priscilla Y. Hsue, Brandy E. Wade, Sharilyn Almodovar, David M. Guidot, Kristi M. Porter, William R. Tyor, Ethan A. Salazar, Robert Alexis Lopez-Astacio, Jaritza Perez Hernandez
Publikováno v:
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Pulmonary Arterial Hypertension (PAH) is overrepresented in People Living with Human Immunodeficiency Virus (PLWH). HIV protein gp120 plays a key role in the pathogenesis of HIV-PAH. Genetic changes in HIV gp120 determine viral interactions with chem