Zobrazeno 1 - 10
of 39
pro vyhledávání: '"David M. Gooden"'
Autor:
David M. Gooden
Publikováno v:
Molbank, Vol 2009, Iss 4, p M638 (2009)
Microwave irradiation of maleimide with an excess of furan in water exclusively yields the corresponding exo-cycloadduct in good yield (87%) in 1 hour at 90 oC. Alkylation of the imido nitrogen with tetraethylene glycol under Mitsunobu conditions giv
Externí odkaz:
https://doaj.org/article/c689e94a4367401f8d663cbfca957e55
Autor:
Hai Yan, Darell D. Bigner, Roger E. McLendon, Yiping He, Giselle Y. Lopez, Rui Yang, B. Ahmed Rasheed, David M. Gooden, Ivan Spasojevic, Christopher G. Duncan, Zachary J. Reitman, Genglin Jin
PDF file-31KB, Synthesis of octyl-�-ketoglutarate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f34e25c83687b1f2a2d7e0fcf63c51d
https://doi.org/10.1158/0008-5472.22396448.v1
https://doi.org/10.1158/0008-5472.22396448.v1
Autor:
Hai Yan, Darell D. Bigner, Roger E. McLendon, Yiping He, Giselle Y. Lopez, Rui Yang, B. Ahmed Rasheed, David M. Gooden, Ivan Spasojevic, Christopher G. Duncan, Zachary J. Reitman, Genglin Jin
PDF file-23KB, D-2HG in cell line lysate samples, as assessed by LC-MS/M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd257fc5b9ef857be37d5d3b0584952
https://doi.org/10.1158/0008-5472.22396433
https://doi.org/10.1158/0008-5472.22396433
Autor:
Hai Yan, Darell D. Bigner, Roger E. McLendon, Yiping He, Giselle Y. Lopez, Rui Yang, B. Ahmed Rasheed, David M. Gooden, Ivan Spasojevic, Christopher G. Duncan, Zachary J. Reitman, Genglin Jin
PDF file-22KB, D-2HG in primary human glioma tissue samples, as assessed by LC-MS/MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5edd7a92e5768c55164736e4c9187c04
https://doi.org/10.1158/0008-5472.22396436.v1
https://doi.org/10.1158/0008-5472.22396436.v1
Autor:
Hai Yan, Darell D. Bigner, Roger E. McLendon, Yiping He, Giselle Y. Lopez, Rui Yang, B. Ahmed Rasheed, David M. Gooden, Ivan Spasojevic, Christopher G. Duncan, Zachary J. Reitman, Genglin Jin
PDF file-101KB, Mutant IDH1 in the absence of wild type IDH1 is not sufficient to efficiently produce D-2HG in HCT116 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd9b4fecbc324cd6deb135d693ed043
https://doi.org/10.1158/0008-5472.22396439
https://doi.org/10.1158/0008-5472.22396439
Autor:
Adam J. Kanack, Michael D. Olp, Oliver J. Newsom, Jamie B. Scaglione, David M. Gooden, Kevin McMahon, Brian C. Smith, K. Matthew Scaglione
Publikováno v:
Chembiochem
The ubiquitin ligase C-terminus of Hsc70 interacting protein (CHIP) is an important regulator of proteostasis. Despite playing an important role in maintaining proteostasis, little progress has been made in developing small molecules that regulate ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994c4b72ac9c5b5bebfc318acbeb154d
https://europepmc.org/articles/PMC9016715/
https://europepmc.org/articles/PMC9016715/
Autor:
P. Lee Ferguson, Kirsten E. Overdahl, Benjamin G. Bobay, Heather M. Stapleton, Gordon J. Getzinger, David M. Gooden
Publikováno v:
Environ Pollut
Azobenzene disperse dyes are the fastest-growing class of dyestuffs, yet little is known about dye occurrences, sources, and transformations; azo dyes are also underrepresented in chemical standard catalogs, molecular databases, and mass spectral lib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4dedb254c238929682575ebce25919b
https://europepmc.org/articles/PMC8434964/
https://europepmc.org/articles/PMC8434964/
Autor:
Harold Walder, Diane Renee Fels, Wayne F. Beyer, Katherine S. Hansen, Alexandru D. Buhimschi, Francis P. Gasparro, Hongwu Jing, David M. Gooden, Mark W. Dewhirst
Publikováno v:
Photochemistry and photobiology, vol 96, iss 5
Photochem Photobiol
Photochem Photobiol
Psoralen is a furocoumarin natural product that intercalates within DNA and forms covalent adducts when activated by ultraviolet radiation. It is well known that this property contributes to psoralen's clinical efficacy in several disease contexts, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afcf67789fff01d171ee95aff1a133f
https://escholarship.org/uc/item/7tk517vc
https://escholarship.org/uc/item/7tk517vc
Autor:
Zachary J. Reitman, Hai Yan, David M. Gooden, Michael R. Zalutsky, Satish K. Chitneni, Rebecca Spicehandler
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:694-699
Mutations in the metabolic enzyme isocitrate dehydrogenase 1 (IDH1) are commonly found in gliomas. AGI-5198, a potent and selective inhibitor of the mutant IDH1 enzyme, was radiolabeled with radioiodine and fluorine-18. These radiotracers were evalua
Autor:
Junqi Lu, Amy E. Ford, April K.S. Salama, Georgia M. Beasley, Anushka Dikshit, David M. Gooden, Yingai J. Jin, Amanda G. Nichols, Huiying Sun, Simone Degan, Jennifer Y. Zhang
Publikováno v:
JID Innovations, Vol 1, Iss 3, Pp 100043-(2021)
JID Innovations
JID Innovations
Increased breakdown of glucose through glycolysis in both aerobic and anaerobic conditions is a hallmark feature of mammalian cancer and leads to increased production of L-lactate. The high-level lactate present within the tumor microenvironment is r