Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David M. Fußhöller"'
Autor:
Rebecca Brinkschulte, David M. Fußhöller, Florian Hoss, Juan F. Rodríguez-Alcázar, Mario A. Lauterbach, Carl-Christian Kolbe, Melanie Rauen, Semra Ince, Christian Herrmann, Eicke Latz, Matthias Geyer
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Analysis of the inflammasome-forming protein NLRP3 provides insights into the function of conserved residues in the ATP-binding site of NLRP3 and the correlation of ATP hydrolysis with inflammasome activation.
Externí odkaz:
https://doaj.org/article/7db49d5d93a84c068f66b8aaa9afe45d
Autor:
Rebecca Brinkschulte, David M. Fußhöller, Florian Hoss, Juan F. Rodríguez-Alcázar, Mario A. Lauterbach, Carl-Christian Kolbe, Melanie Rauen, Semra Ince, Christian Herrmann, Eicke Latz, Matthias Geyer
Publikováno v:
Communications biology. 5(1)
The innate immune system uses inflammasomal proteins to recognize danger signals and fight invading pathogens. NLRP3, a multidomain protein belonging to the family of STAND ATPases, is characterized by its central nucleotide-binding NACHT domain. The
Autor:
Thomas K. Berger, Christoph Brenker, Dagmar Wachten, U. Benjamin Kaupp, Timo Strünker, Normann Goodwin, Eberhard Krause, David M. Fußhöller, Astrid Müller, Nasim Dokani Khesroshahi, Wolfgang Bönigk
Publikováno v:
The Journal of Physiology. 595:1533-1546
Key points In human sperm, proton flux across the membrane is controlled by the voltage-gated proton channel Hv1. We show that sperm harbour both Hv1 and an N-terminally cleaved isoform termed Hv1Sper. The pH-control of Hv1Sper and Hv1 is distinctive