Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David M. Fialho"'
Autor:
Brian J. Cafferty, David M. Fialho, Jaheda Khanam, Ramanarayanan Krishnamurthy, Nicholas V. Hud
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
One of the questions for prebiotic chemistry is the formation of complementary base pairing systems. Here, the authors show that plausible two prebiotic heterocycles can form glycosidic bonds with ribose in water and that these spontaneously base-pai
Externí odkaz:
https://doaj.org/article/929a087411554bbb88a0d9e551908211
Autor:
Joseph R. A. Kincaid, Madison J. Wong, Nnamdi Akporji, Fabrice Gallou, David M. Fialho, Bruce H. Lipshutz
Publikováno v:
Journal of the American Chemical Society. 145:4266-4278
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fff3503067fdc571e1a4970fd23335f
https://doi.org/10.1021/jacs.2c13444
https://doi.org/10.1021/jacs.2c13444
Autor:
Kaitlyn M. Freiberg, Rahul D. Kavthe, Rohan M. Thomas, David M. Fialho, Paris Dee, Matthew Scurria, Bruce H. Lipshutz
Publikováno v:
Chemical science, vol 14, iss 13
Technology for generating especially important amide and peptide bonds from carboxylic acids and amines that avoids traditional coupling reagents is described. The 1-pot processes developed rely on thioester formation, neat, using a simple dithiocarb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6114c7d020cc41dc9aa7277b86d29344
https://doi.org/10.1039/d3sc00198a
https://doi.org/10.1039/d3sc00198a
Autor:
Joseph R. A. Kincaid, Madison J. Wong, Nnamdi Akporji, Fabrice Gallou, David M. Fialho, Bruce H. Lipshutz
Savie is a biodegradable surfactant derived from vitamin E and polysarcosine (PSar) developed for organic synthesis in water. This includes homogeneous catalysis (including examples employing only ppm levels of catalyst), heterogeneous catalysis, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c999a38c817ac082fb9667d7f1e5f274
https://doi.org/10.26434/chemrxiv-2022-bhzns
https://doi.org/10.26434/chemrxiv-2022-bhzns
Autor:
Katherine W Greeson, Isaac Martinez, Nicholas V. Hud, Ramanarayanan Krishnamurthy, Suneesh C. Karunakaran, Gary B. Schuster, David M. Fialho
Publikováno v:
Journal of the American Chemical Society. 143:13525-13537
The mechanism by which informational polymers first formed on the early earth is currently unknown. The RNA world hypothesis implies that RNA oligomers were produced prebiotically, before the emergence of enzymes, but the demonstration of such a proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d34d812c9da242e12d336f2867a2c2c
https://doi.org/10.1021/jacs.1c02287
https://doi.org/10.1021/jacs.1c02287
Autor:
César Menor‐Salván, Bradley T. Burcar, Marcos Bouza, David M. Fialho, Facundo M. Fernández, Nicholas V. Hud
Publikováno v:
Chemistry – A European Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::527ca144a1680a9f5142ae3cc59bbbc1
https://doi.org/10.1002/chem.202201679
https://doi.org/10.1002/chem.202201679
Autor:
César Menor‐Salván, Bradley T. Burcar, Marcos Bouza, David M. Fialho, Facundo M. Fernández, Nicholas V. Hud
Publikováno v:
Chemistry – A European Journal. 28
The prebiotic origins of biopolymers and metabolic co-factors are key questions in Origins of Life studies. In a simple warm-little-pond model, using a drying phase to produce a urea-enriched solution, we present a prebiotic synthetic path for the si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85763709e713049196066a632b6c688a
https://doi.org/10.1002/chem.202200714
https://doi.org/10.1002/chem.202200714
Publikováno v:
The Journal of Organic Chemistry. 85:15337-15346
An efficient, zirconium-catalyzed conversion of unprotected aldose sugars with acetylacetone to polyhydroxyalkyl furans or C-glycosylfurans is reported. The furan products are formed in up to 93% yield using 5-10 mol % ZrCl4. Pentoses are readily con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6082bfea5167aadd193146260b260c34
https://doi.org/10.1021/acs.joc.0c02176
https://doi.org/10.1021/acs.joc.0c02176
Autor:
Marcos Bouza, Nicholas V. Hud, David M. Fialho, Facundo M. Fernández, C. Menor Salván, Bradley T. Burcar
Publikováno v:
ChemBioChem. 21:3504-3510
Urea appears to be a key intermediate of important prebiotic synthetic pathways. Concentrated pools of urea likely existed on the surface of the early Earth, as urea is synthesized in significant quantities from hydrogen cyanide or cyanamide (widely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467734fb9deb4e73791ca3214ac0fbdd
https://doi.org/10.1002/cbic.202000510
https://doi.org/10.1002/cbic.202000510
Publikováno v:
Chemical Reviews. 120:4806-4830
The origin of nucleotides is a major question in origins-of-life research. Given the central importance of RNA in biology and the influential RNA World hypothesis, a great deal of this research has focused on finding possible prebiotic syntheses of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203ff08fd0130cb805266f8dc88f9fb3
https://doi.org/10.1021/acs.chemrev.0c00069
https://doi.org/10.1021/acs.chemrev.0c00069