Zobrazeno 1 - 10
of 67
pro vyhledávání: '"David M. Bernstein"'
Autor:
Julie E. Goodman, Michael J. Becich, David M. Bernstein, Bruce W. Case, Jeffrey H. Mandel, Andre E. Nel, Robert Nolan, Nnaemeka U. Odo, Steven R. Smith, Emanuela Taioli, Graham Gibbs
The presentations in this session of the Monticello II conference were aimed at summarizing what is known about asbestiform and non-asbestiform elongate mineral particles (EMPs) and mesothelioma risks based on evidence from experimental and epidemiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e7878ed81a2dbcc7f1763547d18815
https://escholarship.org/uc/item/1b17b5rt
https://escholarship.org/uc/item/1b17b5rt
Autor:
David M, Bernstein
Publikováno v:
Critical Reviews in Toxicology. 52:89-112
The potential toxic effects of short chrysotile and amphibole asbestos fibers with lengths5 to ∼10 µm have been debated over the years. This stems from the large database of epidemiology, toxicology, and
Autor:
David M, Bernstein, Balazs, Toth, Rick A, Rogers, Peter, Kunzendorf, James I, Phillips, Dirk, Schaudien
Publikováno v:
Toxicology and applied pharmacology. 424
The final results from this multi-dose, 90-day inhalation toxicology study in the rat with life-time post-exposure observation have shown a significant fundamental difference in pathological response and tumorgenicity between brake dust generated fro
Autor:
Rick A. Rogers, David M. Bernstein, P. Kunzendorf, Balazs Toth, J.I. Phillips, Dirk Schaudien
Publikováno v:
Toxicology and Applied Pharmacology. 424:115598
The final results from this multi-dose, 90-day inhalation toxicology study in the rat with life-time post-exposure observation have shown a significant fundamental difference in pathological response and tumorgenicity between brake dust generated fro
Publikováno v:
Annals of the New York Academy of Sciences. 1141:284-303
Risk evaluation and mitigation strategies (REMS) formerly known as Risk Minimization Action Plans (RiskMAPs) are a regulatory technique for dealing with anticipated risks of new medications and are especially important for new drugs with abuse potent
Autor:
Ken Donaldson, Jacques Dunnigan, David M. Bernstein, Fred Pooley, Allen R. Gibbs, John A. Hoskins, Arthur M. Langer
Publikováno v:
Indoor and Built Environment. 16:94-98
In their work on human cancer, the International Agency for Research on Cancer have run a programme of «monographs» that evaluate carcinogenic risk of chemicals to man. The data collected provide considerable information on the risk from substances
Autor:
John A. Hoskins, David M. Bernstein
Publikováno v:
Regulatory Toxicology and Pharmacology. 45:252-264
This review substantiates kinetically and pathologically the differences between chrysotile and amphiboles. The serpentine chrysotile is a thin walled sheet silicate while the amphiboles are double-chain silicates. These different chemistries result
Publikováno v:
Inhalation Toxicology. 17:427-449
Calidria chrysotile asbestos, which is a serpentine mineral, has been shown to be considerably less biopersistent than the durable amphibole mineral tremolite asbestos, which persists once deposited in the lung. The initial results of this inhalation
Autor:
David Y. Lai, Hartwig Muhle, Ken Donaldson, Ernest E. McConnell, David B. Warheit, Vince Castranova, Agnes B. Kane, David M. Bernstein, Günter Oberdörster, Tom Hesterberg, Stephen S. Olin, Jack Hadley, Bice Fubini
Publikováno v:
Inhalation Toxicology. 17:497-537
This working group report is the product of the joint efforts of the members of an expert working group organized and convened by the International Life Sciences Institute Risk Science Institute. A...
Autor:
David M. Bernstein
Publikováno v:
Inhalation Toxicology. 16:675-689
Ventilation of the cigarette was designed to allow dilution of the cigarette smoke and thereby reduce the dose delivered to the smoker. Following the toxicological principle of dose response, a lower concentration of cigarette smoke should be associa