Zobrazeno 1 - 10
of 345
pro vyhledávání: '"David M. Aronoff"'
Publikováno v:
Biomedicine Hub, Vol 9, Iss 1, Pp 31-37 (2024)
Introduction: Folate, vitamin B9, is a water-soluble vitamin that is essential to cellular proliferation and division. In addition to the reduced folate carrier, eukaryotic cells take up folate through endocytosis mediated by one of two GPI-anchored
Externí odkaz:
https://doaj.org/article/58ce0622c45b45c08ff68d5b59ca517a
Autor:
Jennifer A. Gaddy, Rebecca E. Moore, Jonathan S. Lochner, Lisa M. Rogers, Kristen N. Noble, Ayush Giri, David M. Aronoff, David Cliffel, Alison J. Eastman
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionRupture of the gestational membranes often precedes major pregnancy complications, including preterm labor and preterm birth. One major cause of inflammation in the gestational membranes, chorioamnionitis (CAM) is often a result of bacter
Externí odkaz:
https://doaj.org/article/2b1afd0dc0bc403a883daa8f501baa3b
Autor:
Asanda Mtintsilana, Shane A. Norris, Siphiwe N. Dlamini, Lukhanyo H. Nyati, David M. Aronoff, John R. Koethe, Jeffrey A. Goldstein, Alessandra Prioreschi
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background In utero exposure to human immunodeficiency virus (HIV) and antiretroviral (ART) is associated with adverse birth outcomes, which are often attributed to alterations in placental morphology. This study used structural equation mod
Externí odkaz:
https://doaj.org/article/6072755c227d4b3fa53b4d156b7d80d0
Autor:
Elizabeth A. Jasper, Jacklyn N. Hellwege, Jacqueline A. Piekos, Sarah H. Jones, Katherine E. Hartmann, Brian Mautz, David M. Aronoff, Todd L. Edwards, Digna R. Velez Edwards
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The placenta is critical to human growth and development and has been implicated in health outcomes. Understanding the mechanisms through which the placenta influences perinatal and later-life outcomes requires further investigation. We eval
Externí odkaz:
https://doaj.org/article/811a5d94ec764a988035dd8d2f7a3f0c
Autor:
Anup P. Challa, Xinnan Niu, Etoi A. Garrison, Sara L. Van Driest, Lisa M. Bastarache, Ethan S. Lippmann, Robert R. Lavieri, Jeffery A. Goldstein, David M. Aronoff
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-10 (2022)
Challa et al. used 2.8 million electronic health records for proactive pharmacovigilance program development, by rapidly generating and validating hypotheses between medication use during pregnancy and neonatal neurodevelopmental defects. They identi
Externí odkaz:
https://doaj.org/article/284c09bf736649ff9afd1d8e78a51393
Autor:
Michelle L. Korir, Ryan S. Doster, Jacky Lu, Miriam A. Guevara, Sabrina K. Spicer, Rebecca E. Moore, Jamisha D. Francis, Lisa M. Rogers, Kathryn P. Haley, Amondrea Blackman, Kristen N. Noble, Alison J. Eastman, Janice A. Williams, Steven M. Damo, Kelli L. Boyd, Steven D. Townsend, C. Henrique Serezani, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Perinatal infection with Group B Streptococcus (GBS) is associated with preterm birth, neonatal sepsis, and stillbirth. Here, Korir et al. show that gene cadD, encoding a putative metal efflux transporter, is important for metal detoxification, immun
Externí odkaz:
https://doaj.org/article/597dc8cb42f34cfcbcc7b2c564bd3327
Autor:
Alessandra Prioreschi, John R. Koethe, David M. Aronoff, Jeffrey A. Goldstein, Shane A. Norris
Publikováno v:
Obesity Science & Practice, Vol 8, Iss 4, Pp 500-509 (2022)
Abstract Objective Adipose tissue is a central regulator of metabolic health and a contributor to systemic inflammation. Patterns of adiposity deposition are important to understand for optimizing health. This study aimed to asses relationships betwe
Externí odkaz:
https://doaj.org/article/be6857f4330741c891097dbcfefa7846
Autor:
Jacky Lu, Rebecca E. Moore, Sabrina K. Spicer, Ryan S. Doster, Miriam A. Guevara, Jamisha D. Francis, Kristen N. Noble, Lisa M. Rogers, Julie A. Talbert, Michelle L. Korir, Steven D. Townsend, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Streptococcus agalactiae, also known as group B Streptococcus (GBS), is a Gram-positive encapsulated bacterium that colonizes the gastrointestinal tract of 30 to 50% of humans. GBS causes invasive infection during pregnancy that can lead to
Externí odkaz:
https://doaj.org/article/a4dcbca43151424ab3662c888ebec53d
Autor:
Jamisha D. Francis, Miriam A. Guevara, Jacky Lu, Shabir A. Madhi, Gaurav Kwatra, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Streptococcus agalactiae or Group B Streptococcus (GBS) is an encapsulated gram-positive bacterial pathobiont that commonly colonizes the lower gastrointestinal tract and reproductive tract of human hosts. This bacterium can infec
Externí odkaz:
https://doaj.org/article/025e3e037b5f4953a372a109f7f05c55
Autor:
Cole R. McCutcheon, Macy E. Pell, Jennifer A. Gaddy, David M. Aronoff, Margaret G. Petroff, Shannon D. Manning
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Although the neonatal and fetal pathogen Group B Streptococcus (GBS) asymptomatically colonizes the vaginal tract of ∼30% of pregnant women, only a fraction of their offspring develops invasive disease. We and others have postulated that these dimo
Externí odkaz:
https://doaj.org/article/526121ad7f7e4963ba344e04654c8181