Výsledky vyhledávání - "David M. Lynn"

Stimuli-Responsive Polymer Coatings for the Rapid and Tunable Contact Transfer of Plasmid DNA to Soft Surfaces

Autor: Visham Appadoo, Matthew C. D. Carter, James Jennings, Xuanrong Guo, Bo Liu, Timothy A. Hacker, David M. Lynn

Publikováno v: ACS Biomaterials Science & Engineering. 8:4390-4401

We report the design and characterization of thin polymer-based coatings that promote the contact transfer of DNA to soft surfaces under mild and physiologically relevant conditions. Past studies reveal polymer multilayers fabricated using linear pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe12a7511d4f58e26b21600d769bb861
https://doi.org/10.1021/acsbiomaterials.2c00706

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Slippery Antifouling Polymer Coatings Fabricated Entirely from Biodegradable and Biocompatible Components

Autor: Harshit Agarwal, La’Darious J. Quinn, Sahana C. Walter, Thomas J. Polaske, Douglas H. Chang, Sean P. Palecek, Helen E. Blackwell, David M. Lynn

Publikováno v: ACS Appl Mater Interfaces

We report on the design of slippery liquid-infused porous surfaces (SLIPS) fabricated entirely from building blocks that are biodegradable, edible, or generally regarded to be biocompatible. Our approach involves infusion of lubricating oils, includi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d471337b51dd4863f793a78e51fdf9fe
https://pubmed.ncbi.nlm.nih.gov/35394750

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Environmentally Responsive Emulsions of Thermotropic Liquid Crystals with Exceptional Long-Term Stability and Enhanced Sensitivity to Aqueous Amphiphiles

Autor: Oscar H. Piñeres-Quiñones, David M. Lynn, Claribel Acevedo-Vélez

Publikováno v: Langmuir. 38:957-967

We report colloidally stable emulsions of thermotropic liquid crystals (LCs) that can detect the presence of amphiphilic analytes in aqueous environments. Our approach makes use of a Pickering stabilization strategy consisting of surfactant-nanoparti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38efee951c459efe2ca71cc66a96949
https://doi.org/10.1021/acs.langmuir.1c02278

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Controlling the toxicity of biomass-derived difunctional molecules as potential pharmaceutical ingredients for specific activity toward microorganisms and mammalian cells

Autor: Hochan Chang, Douglas H. Chang, Alexios G. Stamoulis, George W. Huber, David M. Lynn, Sean P. Palecek, James A. Dumesic

Publikováno v: Green Chemistry.

A biomass-derived difuran molecule can be converted to difunctional compounds by Diels–Alder reaction with N-substituted maleimides. Acid-catalyzed retro Diels–Alder reaction of difunctional compounds can promote the eradication of microorganisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61563752b45a3c660522c3ff851e3ae0
https://doi.org/10.1039/d3gc00188a

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Interactions of Bacterial Quorum Sensing Signals with Model Lipid Membranes: Influence of Acyl Tail Structure on Multiscale Response

Autor: Helen E. Blackwell, Reid C. Van Lehn, David M. Lynn, Curran G Gahan

Publikováno v: Langmuir

Many common bacteria use amphiphilic N-acyl-L-homoserine lactones (AHLs) as signaling molecules to coordinate group behaviors at high cell densities. Past studies demonstrate that AHLs can adsorb to and promote the remodeling of lipid membranes in wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc446528e5fe978a8aaa057f59bf034
https://doi.org/10.1021/acs.langmuir.1c01825

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Akademický článek

Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species

Autor: Namrata Raman, Myung-Ryul Lee, David M. Lynn, Sean P. Palecek

Publikováno v: Pharmaceuticals, Vol 8, Iss 3, Pp 483-503 (2015)

Candida albicans is the most prevalent cause of fungal infections and treatment is further complicated by the formation of drug resistant biofilms, often on the surfaces of implanted medical devices. In recent years, the incidence of fungal infection

Externí odkaz: https://doaj.org/article/13838478f92e4869bc1d464ad0497396

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Interactions of Bacterial Quorum Sensing Signals with Model Lipid Membranes: Influence of Membrane Composition on Membrane Remodeling

Autor: Curran G. Gahan, Reid C. Van Lehn, Helen E. Blackwell, David M. Lynn

Publikováno v: Langmuir : the ACS journal of surfaces and colloids.

We report the influence of membrane composition on the multiscale remodeling of multicomponent lipid bilayers initiated by contact with the amphiphilic bacterial quorum sensing signal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8c32ee0335e2b120801dfe993829eb
https://pubmed.ncbi.nlm.nih.gov/36534123

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Bacterial Quorum Sensing Signals Promote Large-Scale Remodeling of Lipid Membranes

Autor: Helen E. Blackwell, Curran G Gahan, David M. Lynn, Daniel E Manson, Zachary J Ehmer, Samarthaben J. Patel, Reid C. Van Lehn, Lawrence M Chen

Publikováno v: Langmuir

We report that N-acyl-l-homoserine lactones (AHLs), a class of nonionic amphiphiles that common bacteria use as signals to coordinate group behaviors, can promote large-scale remodeling in model lipid membranes. Characterization of supported lipid bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a25e6c425e48102e1b91e78b7de7c54
https://doi.org/10.1021/acs.langmuir.1c01204

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