Zobrazeno 1 - 10
of 78
pro vyhledávání: '"David M Stevenson"'
Autor:
Courtney E McDougal, Zachary T Morrow, Tighe Christopher, Seonyoung Kim, Drake Carter, David M Stevenson, Daniel Amador-Noguez, Mark J Miller, John-Demian Sauer
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009493 (2021)
Listeria monocytogenes is an intracellular bacterium that elicits robust CD8+ T-cell responses. Despite the ongoing development of L. monocytogenes-based platforms as cancer vaccines, our understanding of how L. monocytogenes drives robust CD8+ T-cel
Externí odkaz:
https://doaj.org/article/70d5aed845d64ce69478e83c864f8843
Autor:
Taylor B Updegrove, Jailynn Harke, Vivek Anantharaman, Jin Yang, Nikhil Gopalan, Di Wu, Grzegorz Piszczek, David M Stevenson, Daniel Amador-Noguez, Jue D Wang, L Aravind, Kumaran S Ramamurthi
Publikováno v:
eLife, Vol 10 (2021)
Hydrolysis of nucleoside triphosphates releases similar amounts of energy. However, ATP hydrolysis is typically used for energy-intensive reactions, whereas GTP hydrolysis typically functions as a switch. SpoIVA is a bacterial cytoskeletal protein th
Externí odkaz:
https://doaj.org/article/60e6f33030a8422a98d7eba95a455126
Autor:
Garret Suen, Paul J Weimer, David M Stevenson, Frank O Aylward, Julie Boyum, Jan Deneke, Colleen Drinkwater, Natalia N Ivanova, Natalia Mikhailova, Olga Chertkov, Lynne A Goodwin, Cameron R Currie, David Mead, Phillip J Brumm
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18814 (2011)
Fibrobacter succinogenes is an important member of the rumen microbial community that converts plant biomass into nutrients usable by its host. This bacterium, which is also one of only two cultivated species in its phylum, is an efficient and prolif
Externí odkaz:
https://doaj.org/article/14a5ec0919d84973a80ed1cad43d5998
Autor:
Daniel A. Pensinger, Horia A. Dobrila, David M. Stevenson, Nicole D. Hryckowian, Daniel Amador-Noguez, Andrew J. Hryckowian
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT The gut microbiome engenders colonization resistance against the diarrheal pathogen Clostridioides difficile, but the molecular basis of this colonization resistance is incompletely understood. A prominent class of gut microbiome-produced me
Externí odkaz:
https://doaj.org/article/41fe5440e23740f4a1f938cdd0bc569d
Autor:
Daven B. Khana, Mehmet Tatli, Julio Rivera Vazquez, Sarathi M. Weraduwage, Noah Stern, Alexander S. Hebert, Edna Angelica Trujillo, David M. Stevenson, Joshua J. Coon, Thomas D. Sharky, Daniel Amador-Noguez
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT Zymomonas mobilis is an industrially relevant aerotolerant anaerobic bacterium that can convert up to 96% of consumed glucose to ethanol. This highly catabolic metabolism could be leveraged to produce isoprenoid-based bioproducts via the met
Externí odkaz:
https://doaj.org/article/915f3e829112403a8b8e2cf70a06ac20
Autor:
Danny K. Fung, Kaihong Bai, Jin Yang, Xiaoli Xu, David M. Stevenson, Daniel Amador-Noguez, Laixin Luo, Jue D. Wang
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Small alarmone hydrolases (SAHs) are alarmone metabolizing enzymes found in both metazoans and bacteria. In metazoans, the SAH homolog Mesh1 is reported to function in cofactor metabolism by hydrolyzing NADPH to NADH. In bacteria, SAHs are o
Externí odkaz:
https://doaj.org/article/c19b7059797f4a6eb86cb3489880e018
Autor:
Shuen, Hon, Tyler, Jacobson, David M, Stevenson, Marybeth I, Maloney, Richard J, Giannone, Robert L, Hettich, Daniel, Amador-Noguez, Daniel G, Olson, Lee R, Lynd
Publikováno v:
Appl Environ Microbiol
Glycolysis is an ancient, widespread, and highly conserved metabolic pathway that converts glucose into pyruvate. In the canonical pathway, the phosphofructokinase (PFK) reaction plays an important role in controlling flux through the pathway. Clostr
Autor:
Julia I. Martien, Alexander S. Hebert, David M. Stevenson, Matthew R. Regner, Daven B. Khana, Joshua J. Coon, Daniel Amador-Noguez
Publikováno v:
mSystems, Vol 4, Iss 1 (2019)
ABSTRACT Zymomonas mobilis is an aerotolerant anaerobe and prolific ethanologen with attractive characteristics for industrial bioproduct generation. However, there is currently insufficient knowledge of the impact that environmental factors have on
Externí odkaz:
https://doaj.org/article/1334585791074c9bb696edfe11a9d3ba
Publikováno v:
bioRxiv
Listeria monocytogenesis a remarkably well-adapted facultative intracellular pathogen that can thrive in a wide range of ecological niches.L. monocytogenesmaximizes its ability to generate energy from diverse carbon sources using a respiro-fermentati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc9a7266a698e0582becc655e9b38fa
https://europepmc.org/articles/PMC9882099/
https://europepmc.org/articles/PMC9882099/
Autor:
Shuen Hon, Tyler Jacobson, David M. Stevenson, Marybeth I. Maloney, Richard J. Giannone, Robert L. Hettich, Daniel Amador-Noguez, Daniel G. Olson, Lee R. Lynd
Publikováno v:
Applied and Environmental Microbiology. 88
The ability to control the distribution of thermodynamic driving force throughout a metabolic pathway is likely to be an important tool for metabolic engineering. The phosphofructokinase reaction is a key enzyme in Embden-Mayerhof-Parnas glycolysis a