Zobrazeno 1 - 10
of 1 301
pro vyhledávání: '"David M Smith"'
Could a Common Mechanism of Protein Degradation Impairment Underlie Many Neurodegenerative Diseases?
Autor:
David M Smith
Publikováno v:
Journal of Experimental Neuroscience, Vol 12 (2018)
At the cellular level, many neurodegenerative diseases (NDs), often considered proteinopathies, are characterized by the accumulation of misfolded and damaged proteins into large insoluble aggregates. Prominent species that accumulate early and play
Externí odkaz:
https://doaj.org/article/b612d2e103cf4e169ffa3f4b3e90fb07
Autor:
Licurgo Benemann Almeida, Owen Dean, Marco Idiart, Sasha Devore, David M Smith, Christiane Linster
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
In the olfactory system, cholinergic modulation has been associated with contrast modulation and changes in receptive fields in the olfactory bulb, as well the learning of odor associations in olfactory cortex. Computational modeling and behavioral s
Externí odkaz:
https://doaj.org/article/51ecb0e975474d2f8249e0285144d00b
Publikováno v:
International Journal of Integrated Care, Vol 14, Iss 8 (2014)
Externí odkaz:
https://doaj.org/article/2ce4f56fb0f84f03999349b3a1a6eb71
Publikováno v:
Frontiers in Human Neuroscience, Vol 8 (2014)
Spatial navigation requires representations of landmarks and other navigation cues. The retrosplenial cortex (RSC) is anatomically positioned between limbic areas important for memory formation, such as the hippocampus and the anterior thalamus, and
Externí odkaz:
https://doaj.org/article/08a4b8aabc744c41817eb33bc3e5ecc2
Autor:
Mikael Bjursell, Xiufeng Xu, Therése Admyre, Gerhard Böttcher, Sofia Lundin, Ralf Nilsson, Virginia M Stone, Noel G Morgan, Yan Y Lam, Leonard H Storlien, Daniel Lindén, David M Smith, Mohammad Bohlooly-Y, Jan Oscarsson
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114942 (2014)
GPR120 (Ffar4) has been postulated to represent an important receptor mediating the improved metabolic profile seen upon ingestion of a diet enriched in polyunsaturated fatty acids (PUFAs). GPR120 is highly expressed in the digestive system, adipose
Externí odkaz:
https://doaj.org/article/484465c51f7048c088e91a0e6698af4a
Autor:
Martin Glaser, Jörg Schnauß, Teresa Tschirner, B U Sebastian Schmidt, Maximilian Moebius-Winkler, Josef A Käs, David M Smith
Publikováno v:
New Journal of Physics, Vol 18, Iss 5, p 055001 (2016)
The self-assembly of molecular and macromolecular building blocks into organized patterns is a complex process found in diverse systems over a wide range of size and time scales. The formation of star- or aster-like configurations, for example, is a
Externí odkaz:
https://doaj.org/article/f3a7eeb025fe48469d88bd9a6fee2e71
Autor:
Marika Orlov, Florin Vaida, Olivia C Finney, David M Smith, Angela K Talley, Ruobing Wang, Stefan H Kappe, Qianqian Deng, Robert T Schooley, Patrick E Duffy
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39000 (2012)
Co-infection with HIV and P. falciparum worsens the prognosis of both infections; however, the mechanisms driving this adverse interaction are not fully delineated. To evaluate this, we studied HIV-1 and P. falciparum interactions in vitro using peri
Externí odkaz:
https://doaj.org/article/23eea0e3cb494dc2917828edbc0e9d5c
Autor:
Grace Q. Gong, Benoit Bilanges, Ben Allsop, Glenn R. Masson, Victoria Roberton, Trevor Askwith, Sally Oxenford, Ralitsa R. Madsen, Sarah E. Conduit, Dom Bellini, Martina Fitzek, Matt Collier, Osman Najam, Zhenhe He, Ben Wahab, Stephen H. McLaughlin, A. W. Edith Chan, Isabella Feierberg, Andrew Madin, Daniele Morelli, Amandeep Bhamra, Vanesa Vinciauskaite, Karen E. Anderson, Silvia Surinova, Nikos Pinotsis, Elena Lopez-Guadamillas, Matthew Wilcox, Alice Hooper, Chandni Patel, Maria A. Whitehead, Tom D. Bunney, Len R. Stephens, Phillip T. Hawkins, Matilda Katan, Derek M. Yellon, Sean M. Davidson, David M. Smith, James B. Phillips, Richard Angell, Roger L. Williams, Bart Vanhaesebroeck
Publikováno v:
Nature. 618:159-168
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8f8e36156cc591a3aec34b2fffc9688
https://doi.org/10.1038/s41586-023-05972-2
https://doi.org/10.1038/s41586-023-05972-2
Publikováno v:
SLAS Discovery. 28:3-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1326b6271e01b289554499289513fbdd
https://doi.org/10.1016/j.slasd.2023.01.002
https://doi.org/10.1016/j.slasd.2023.01.002
Autor:
David M. Smith
This final volume of the Heads of Religious Houses: England and Wales series takes the lists of monastic superiors from 1377 to the dissolution of the monastic houses ending in 1540 and so concludes a reference work covering six hundred years of mona
