Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David M Savastano"'
Autor:
Susan M Schwartz, David M Savastano
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 56:476-481
Objective Examine inhibition of dietary fat absorption with orlistat tablets (24, 36, 48, 72, and 144 mg) vs. 60-mg orlistat capsule. Materials and methods 83 overweight/obese subjects randomized to 1 of 6 open-label treatments. Pre- vs. post-treatme
Publikováno v:
International journal of clinical pharmacology and therapeutics. 55(7)
Objective Evaluate adherence of US consumers to proposed label directions for a new 400 mg ibuprofen formulation. Methods In this single-arm, open-label, multicenter, 30-day study simulating an over-the-counter (OTC)-like environment, US analgesic co
Autor:
Jack A. Yanovski, Sheila M. Brady, James C. Reynolds, David M Savastano, Henry S. Eden, Alexander M. Gorbach
Publikováno v:
The American Journal of Clinical Nutrition. 90:1124-1131
Background: Human obesity is associated with increased heat production; however, subcutaneous adipose tissue provides an insulating layer that impedes heat loss. To maintain normothermia, therefore, obese individuals must increase their heat dissipat
Autor:
Cong Ning, Laura E. Wolkoff, Roberto E Figueroa, Rachael A Sorg, Caroline A. Roza, Marian Tanofsky-Kraff, Kavitha Anandalingam, Sheila M. Brady, Merel Kozlosky, Joan C. Han, Jack A. Yanovski, David M Savastano, Kyra S. Jefferson-George, Ethan L. Sanford, Dale A. Schoeller
Publikováno v:
The American Journal of Clinical Nutrition. 90:912-920
Background: Homozygosity for 2 protein-altering polymorphisms in the melanocortin-3 receptor gene (MC3R) coding sequence, C17A and G241A, has been reported to be associated with an obesity phenotype in children, yet how these polymorphisms affect ene
Autor:
James C. Reynolds, Marian Tanofsky-Kraff, Natasha A. Schvey, David M Savastano, Susan Z. Yanovski, Lauren B. Shomaker, Jenna M. Checchi, Jack A. Yanovski, Sheila M. Brady, Lisa M. Ranzenhofer, Lisa B. Yanoff
Publikováno v:
Journal of Adolescent Health. 45:33-39
To examine the relationships between cognitive eating restraint and both bone mineral density (BMD) and markers of bone turnover in overweight adolescents.One hundred thirty-seven overweight (BMI 39.1 +/- 6.8 kg/m(2)) African American and Caucasian a
Autor:
Mihai Covasa, David M. Savastano
Publikováno v:
Physiology & Behavior. 92:434-442
Previous studies demonstrate that cholecystokinin type-1 (CCK(1)) and serotonin type-3 (5-HT(3)) dependent pathways are independently involved in intestinal nutrient-induced meal termination. In the current study, we employed selective antagonists to
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 292:R1063-R1070
Several gastrointestinal stimuli, including some intestinal nutrients, have been shown to exert their satiating effect via activation of serotonin type-3 (5-HT3) receptors. The presence of lipids in the small intestine potently suppresses food intake
Publikováno v:
Physiology & Behavior. 82:663-669
Recent evidence supports a role for the serotonin-3 (5-HT3) receptors in the modulation of cholecystokinin (CCK)-induced satiation. Likewise, 5-HT's anorectic response has been linked to recruitment of peripheral CCK-A receptors. Evidence to date, ho
Publikováno v:
Nutrition Journal
Background Dietary carbohydrates may affect metabolic and physiologic parameters. The present study evaluated whether a combination of two dietary fibers, oligofructose (OFS) and pectin (P), altered satiety and glycemic parameters. The primary object
Autor:
Christopher Diefenbach, Sheila G. West, Deborah M Bagshaw, David M. Savastano, Penny M. Kris-Etherton, Colin D. Kay, Sarah K Gebauer
Nut consumption reduces cardiovascular risk, and reductions in blood pressure and peripheral vascular resistance may be important mediators of this relationship. We evaluated effects of pistachios on flow-mediated dilation and blood pressure response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e70f306934f948b2744d4556d70c5e
https://europepmc.org/articles/PMC3862178/
https://europepmc.org/articles/PMC3862178/