Zobrazeno 1 - 10
of 11
pro vyhledávání: '"David M McLendon"'
Publikováno v:
Psychopharmacologia. 37:23-29
Harnessed rhesus monkeys, surgically prepared with indwelling jugular catheters, were given access by means of remotely controlled infusion pumps to unlimited quantities of delta-9-trans-tetrahydrocannabinol. Naive monkeys as well as monkeys which we
Publikováno v:
Pharmacology Biochemistry and Behavior. 7:117-120
Three studies assessed the time course of inhibition of predatory aggression and changes in levels of brain serotonin following administration of Δ 9 -THC. In Study One, six groups of six rats each were administered 1.25 mg/kg Δ 9 -THC IV and frog-
Publikováno v:
Psychopharmacology. 50:159-163
Using classical conditioning procedures, the cardiac conditioned response (CCR) was established by pairing one of two tones with the delivery of a peripheral electric shock in Rhesus monkeys. The other tone had no terminal consequence. Such a procedu
Publikováno v:
Psychopharmacologia. 26:297-306
In two separate experiments effects were evaluated of chronic administration of δ-9-THC (i.v.) on the behavior of rhesus monkeys trained on a multiple schedule of food reinforcement and a shock avoidance schedule. Rapid tolerance to drug effect was
Publikováno v:
Nature. 238:463-465
MARIJUANA and its active major ingredient, Δ-9-tetrahydrocan-nabinol (THC), reduce fighting among previously isolated mice1 and decrease preference for the side of a T-maze where they are rewarded by the opportunity to attack2. The degree of suppres
Publikováno v:
The Journal of international medical research. 9(3)
Recently, it has been argued that benzodiazepines may not be safe or efficacious beyond 3 months continuous dosage. This study was designed to provide data regarding efficacy, safety, possible tolerance development, and possible withdrawal effects of
Autor:
Robert T. Harris, David M McLendon
Publikováno v:
Cocaine and Other Stimulants ISBN: 9781468430899
Suppression of ongoing positively reinforced behavior by the presentation of aversive stimuli has been reported in some cases while facilitation of such behavior has been noted in other instances. A major variable in these studies is the contingency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49e8cb151d4b922391c36144f2385480
https://doi.org/10.1007/978-1-4684-3087-5_28
https://doi.org/10.1007/978-1-4684-3087-5_28
Publikováno v:
Psychopharmacology. 79(4)
This was a 4-week, three-center, double-blind, randomized, parallel, placebo-controlled evaluation of the efficacy and safety of bupropion in hospitalized depressed patients. Results from 27 placebo and 48 bupropion-treated patients were analyzed for
Autor:
Louis F. Fabre, David M McLendon
Publikováno v:
Journal of clinical pharmacology. 21(S1)
The anxiolytic properties of nabilone, a synthetic cannabinoid resembling the natural cannabinoids, were studied in 25 outpatients suffering from anxiety. The drug was compared with a placebo in a double-blind manner over a 28-day treatment period. P
Publikováno v:
The Journal of international medical research. 7(2)
This study compared prazepam with diazepam, chlorazepate dipotassium, and placebo in the treatment of anxious out-patients. Patients were screened for participation in the study to be sure they met the criteria for inclusion. Patients were excluded i