Zobrazeno 1 - 10
of 73
pro vyhledávání: '"David M Maclean"'
Autor:
Tyler Couch, Kyle D Berger, Dana L Kneisley, Tyler W McCullock, Paul Kammermeier, David M Maclean
Publikováno v:
eLife, Vol 10 (2021)
Acid-sensing ion channels (ASICs) are trimeric cation-selective channels activated by decreases in extracellular pH. The intracellular N and C terminal tails of ASIC1 influence channel gating, trafficking, and signaling in ischemic cell death. Despit
Externí odkaz:
https://doaj.org/article/460f92cce11d4f5d8f0067e9e9433851
Publikováno v:
eLife, Vol 9 (2020)
Acid-sensing ion channels (ASICs) are neuronal sodium-selective channels activated by reductions in extracellular pH. Structures of the three presumptive functional states, high-pH resting, low-pH desensitized, and toxin-stabilized open, have all bee
Externí odkaz:
https://doaj.org/article/2914653332f5469fa8a86b5e76b7d4de
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0219886 (2020)
Förster Resonance Energy Transfer (FRET) has become an immensely powerful tool to profile intra- and inter-molecular interactions. Through fusion of genetically encoded fluorescent proteins (FPs) researchers have been able to detect protein oligomer
Externí odkaz:
https://doaj.org/article/610f00fac0fe4bd485faa6e6cd1d57c0
Autor:
Jinjun Chen, Lingyong Li, Shao-Rui Chen, Hong Chen, Jing-Dun Xie, Rita E. Sirrieh, David M. MacLean, Yuhao Zhang, Meng-Hua Zhou, Vasanthi Jayaraman, Hui-Lin Pan
Publikováno v:
Cell Reports, Vol 38, Iss 4, Pp 110308- (2022)
Externí odkaz:
https://doaj.org/article/6f495f000171454ebd6396114d09ed80
Autor:
David M. MacLean, Enrique Soto
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/402f9830cd4148aa8d2bbd341cb3fbf8
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Structures of the trimeric acid-sensing ion channel have been solved in the resting, toxin-bound open and desensitized states. Within the extracellular domain, there is little difference between the toxin-bound open state and the desensitized state.
Externí odkaz:
https://doaj.org/article/6d8fd25387bc46e9a27a83f62a2a78f1
Autor:
Karl, Foley, Haider, Altimimi, Hailong, Hou, Yu, Zhang, Cody, McKee, Makaía M, Papasergi-Scott, Hongtian, Yang, Abigail, Mayer, Nancy, Ward, David M, MacLean, Angus C, Nairn, David, Stellwagen, Houhui, Xia
Publikováno v:
Frontiers in synaptic neuroscience. 14
Inhibitor-2 (I-2) is a prototypic inhibitor of protein phosphatase-1 (PP1), a major serine-threonine phosphatase that regulates synaptic plasticity and learning and memory. Although I-2 is a potent inhibitor of PP1
Publikováno v:
J Physiol
Acid-sensing ion channels (ASICs) are a class of trimeric cation-selective ion channels activated by changes in pH within the physiological range. They are widely expressed in the central and peripheral nervous systems where they participate in a ran
Autor:
Karl Foley, Haider Altimimi, Hailong Hou, Yu Zhang, Cody McKee, Makaía M. Papasergi-Scott, Hongtian Yang, Abigail Mayer, Nancy Ward, David M. MacLean, Angus C. Nairn, David Stellwagen, Houhui Xia
Inhibitor-2 (I-2) is a prototypic inhibitor of protein phosphatase-1 (PP1), a major serine-threonine phosphatase that regulates synaptic plasticity and learning and memory. Although I-2 is a potent inhibitor of PP1 in vitro, our previous work has elu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c0a884b7cbf2365f69edec67d359ee
https://doi.org/10.1101/2022.02.10.480004
https://doi.org/10.1101/2022.02.10.480004