Zobrazeno 1 - 10
of 113
pro vyhledávání: '"David M Lubaroff"'
Autor:
Peng Li, Amani Makkouk, Jennifer Gordetsky, Eddy Yang, Lewis Thomas, Yousef Zakharia, George J Weiner, Aliasger K Salem, Lakshminarayanan Nandagopal, Hesham Yasin, Rohan Garje, Shannon K Boi, Rachael M Orlandella, Justin Tyler Gibson, William James Turbitt, Gal Wald, Claire Buchta Rosean, Katlyn E Norris, Megan Bing, Laura Bertrand, Brett P Gross, Dmytro Starenki, Kristine I Farag, Robert E Sorge, James A Brown, David M Lubaroff, Rebecca C Arend, Kenneth Nepple, Tatiana T Marquez-Lago, Lyse A Norian
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Obesity is a major risk factor for renal cancer, yet our understanding of its effects on antitumor immunity and immunotherapy outcomes remains incomplete. Deciphering these associations is critical, given the growing clinical use of immune
Externí odkaz:
https://doaj.org/article/e32b1f2582bd4a1abceb494628d92ae8
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67904 (2013)
Standard cancer therapies, particularly those involving chemotherapy, are in need of modifications that both reduce short-term and long-term side effects as well as improve the overall survival of cancer patients. Here we show that combining low-dose
Externí odkaz:
https://doaj.org/article/a1df3ef5468541b39daaff1909271819
Autor:
Lyse A. Norian, Rohan Garje, Lewis Thomas, Shannon K. Boi, Rebecca C. Arend, Claire Buchta Rosean, Brett P. Gross, Lakshminarayanan Nandagopal, David M. Lubaroff, Rachael M. Orlandella, Kenneth G. Nepple, Dmytro Starenki, William J. Turbitt, George J. Weiner, Katlyn E Norris, Gal Wald, Kristine I Farag, Megan Bing, Eddy S. Yang, Jennifer B. Gordetsky, Robert E. Sorge, Amani Makkouk, Hesham A Yasin, James A. Brown, Peng Li, Justin T. Gibson, Tatiana T. Marquez-Lago, Yousef Zakharia, Laura A. Bertrand, Aliasger K. Salem
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundObesity is a major risk factor for renal cancer, yet our understanding of its effects on antitumor immunity and immunotherapy outcomes remains incomplete. Deciphering these associations is critical, given the growing clinical use of immune
Autor:
Donna M. Farley, Laila Dahmoush, Premal H. Thaker, Lauren Z. Davis, Kristian E. Markon, Michael J. Goodheart, David M. Lubaroff, David Bender, Susan K. Lutgendorf, Steve W. Cole, Frank J. Penedo, George M. Slavich, Anil K. Sood
Publikováno v:
Cancer. 121:3543-3550
BACKGROUND The impact of psychological well-being on the physiologic processes involved in cancer progression remains unclear. Prior research has implicated adrenergic signaling in tumor growth and metastasis. Given that adrenergic signaling is influ
Publikováno v:
Immunologic Research. 59:236-242
Immunotherapy has been investigated in both preclinical studies and clinical trials as a new therapy for prostate cancer. Vaccines, including those that utilize dendritic cells, viruses, or DNA, immunize against prostate-specific antigen and prostati
Publikováno v:
Nature Reviews Urology. 10:149-160
In this Review, Geary and colleagues discuss the potential mechanisms of action for all prostate cancer vaccines that trigger cytotoxic-T-lymphocyte-mediated responses and have reached clinical trials. They consider ways in which key immune events ar
Autor:
Laila Dahmoush, Steven W. Cole, Anil K. Sood, Amina Ahmed, Premal H. Thaker, Michael J. Goodheart, Koen De Geest, Frank J. Penedo, Susan K. Lutgendorf, Joseph A. Lucci, David Bender, Luis Mendez, David M. Lubaroff, Parvin Ganjei-Azar, George M. Slavich, M. Bridget Zimmerman
Publikováno v:
Journal of Clinical Oncology. 30:2885-2890
Purpose Previous research has demonstrated relationships of social support with disease-related biomarkers in patients with ovarian cancer. However, the clinical relevance of these findings to patient outcomes has not been established. This prospecti
Autor:
Laila Dahmoush, Michael J. Goodheart, Thomas E. Buekers, Lauren Clevenger, David M. Lubaroff, Donna B. Farley, Anil K. Sood, David Bender, Susan K. Lutgendorf, Koen DeGeest, Gina Krueger, Steve W. Cole, Luis Mendez, Frank J. Penedo
Publikováno v:
Brain, Behavior, and Immunity. 25:250-255
Noradrenergic pathways have been implicated in growth and progression of ovarian cancer. Intratumoral norepinephrine (NE) has been shown to increase with stress in an animal cancer model, but little is known regarding how tumor NE varies with disease
Autor:
Bridget Zimmerman, David M. Lubaroff, Donald M. Lamkin, Douglas R. Spitz, Anil K. Sood, Daniel J. Lenihan, Mian M.K. Shahzad, Eileen H. Shinn, Susan K. Lutgendorf, Koen DeGeest
Publikováno v:
Cancer. 115:1021-1027
BACKGROUND: Research suggests that glucose levels in cancer patients may be an important prognostic indicator. In ovarian tumors, increased expression of glucose transporter 1 (GLUT1), a transmembrane protein responsible for glucose uptake, is relate
Autor:
David M. Lubaroff, Dev Karan
Publikováno v:
Advanced Drug Delivery Reviews. 61:268-274
The use of an adenovirus transduced to express a prostate cancer antigen (PSA) as a vaccine for the treatment of prostate cancer has been shown to be active in the destruction of antigen-expressing prostate tumor cells in a pre-clinical model, using