Zobrazeno 1 - 10
of 266
pro vyhledávání: '"David M Lubaroff"'
Autor:
Peng Li, Amani Makkouk, Jennifer Gordetsky, Eddy Yang, Lewis Thomas, Lakshminarayanan Nandagopal, Hesham Yasin, Rohan Garje, Shannon K Boi, Rachael M Orlandella, Justin Tyler Gibson, William James Turbitt, Gal Wald, Claire Buchta Rosean, Katlyn E Norris, Megan Bing, Laura Bertrand, Brett P Gross, Dmytro Starenki, Kristine I Farag, Robert E Sorge, James A Brown, David M Lubaroff, Rebecca C Arend, Kenneth Nepple, Tatiana T Marquez-Lago, Lyse A Norian
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Obesity is a major risk factor for renal cancer, yet our understanding of its effects on antitumor immunity and immunotherapy outcomes remains incomplete. Deciphering these associations is critical, given the growing clinical use of immune
Externí odkaz:
https://doaj.org/article/e32b1f2582bd4a1abceb494628d92ae8
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67904 (2013)
Standard cancer therapies, particularly those involving chemotherapy, are in need of modifications that both reduce short-term and long-term side effects as well as improve the overall survival of cancer patients. Here we show that combining low-dose
Externí odkaz:
https://doaj.org/article/a1df3ef5468541b39daaff1909271819
Autor:
Lyse A. Norian, Rohan Garje, Lewis Thomas, Shannon K. Boi, Rebecca C. Arend, Claire Buchta Rosean, Brett P. Gross, Lakshminarayanan Nandagopal, David M. Lubaroff, Rachael M. Orlandella, Kenneth G. Nepple, Dmytro Starenki, William J. Turbitt, George J. Weiner, Katlyn E Norris, Gal Wald, Kristine I Farag, Megan Bing, Eddy S. Yang, Jennifer B. Gordetsky, Robert E. Sorge, Amani Makkouk, Hesham A Yasin, James A. Brown, Peng Li, Justin T. Gibson, Tatiana T. Marquez-Lago, Yousef Zakharia, Laura A. Bertrand, Aliasger K. Salem
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundObesity is a major risk factor for renal cancer, yet our understanding of its effects on antitumor immunity and immunotherapy outcomes remains incomplete. Deciphering these associations is critical, given the growing clinical use of immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3c7bacc0043b7241bd1cd491a6be2c
https://jitc.bmj.com/content/8/2/e000725.full
https://jitc.bmj.com/content/8/2/e000725.full
Autor:
Donna M. Farley, Laila Dahmoush, Premal H. Thaker, Lauren Z. Davis, Kristian E. Markon, Michael J. Goodheart, David M. Lubaroff, David Bender, Susan K. Lutgendorf, Steve W. Cole, Frank J. Penedo, George M. Slavich, Anil K. Sood
Publikováno v:
Cancer. 121:3543-3550
BACKGROUND The impact of psychological well-being on the physiologic processes involved in cancer progression remains unclear. Prior research has implicated adrenergic signaling in tumor growth and metastasis. Given that adrenergic signaling is influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e97c50de3d9290e738de9c0f96a89af
https://doi.org/10.1002/cncr.29516
https://doi.org/10.1002/cncr.29516
Publikováno v:
Immunologic Research. 59:236-242
Immunotherapy has been investigated in both preclinical studies and clinical trials as a new therapy for prostate cancer. Vaccines, including those that utilize dendritic cells, viruses, or DNA, immunize against prostate-specific antigen and prostati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dbb05ba0f462e7f854563440f2a565
https://doi.org/10.1007/s12026-014-8532-1
https://doi.org/10.1007/s12026-014-8532-1
Publikováno v:
Nature Reviews Urology. 10:149-160
In this Review, Geary and colleagues discuss the potential mechanisms of action for all prostate cancer vaccines that trigger cytotoxic-T-lymphocyte-mediated responses and have reached clinical trials. They consider ways in which key immune events ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1afbc8f4e1c986d0b782aa6eefd58e0e
https://doi.org/10.1038/nrurol.2013.8
https://doi.org/10.1038/nrurol.2013.8
Autor:
Laila Dahmoush, Steven W. Cole, Anil K. Sood, Amina Ahmed, Premal H. Thaker, Michael J. Goodheart, Koen De Geest, Frank J. Penedo, Susan K. Lutgendorf, Joseph A. Lucci, David Bender, Luis Mendez, David M. Lubaroff, Parvin Ganjei-Azar, George M. Slavich, M. Bridget Zimmerman
Publikováno v:
Journal of Clinical Oncology. 30:2885-2890
Purpose Previous research has demonstrated relationships of social support with disease-related biomarkers in patients with ovarian cancer. However, the clinical relevance of these findings to patient outcomes has not been established. This prospecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13916012227189bb931fd96f970d823f
https://doi.org/10.1200/jco.2011.39.4411
https://doi.org/10.1200/jco.2011.39.4411
Autor:
Laila Dahmoush, Michael J. Goodheart, Thomas E. Buekers, Lauren Clevenger, David M. Lubaroff, Donna B. Farley, Anil K. Sood, David Bender, Susan K. Lutgendorf, Koen DeGeest, Gina Krueger, Steve W. Cole, Luis Mendez, Frank J. Penedo
Publikováno v:
Brain, Behavior, and Immunity. 25:250-255
Noradrenergic pathways have been implicated in growth and progression of ovarian cancer. Intratumoral norepinephrine (NE) has been shown to increase with stress in an animal cancer model, but little is known regarding how tumor NE varies with disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f1187bdb20a34950d0234bdff2eeb2
https://doi.org/10.1016/j.bbi.2010.10.012
https://doi.org/10.1016/j.bbi.2010.10.012
Autor:
Bridget Zimmerman, David M. Lubaroff, Donald M. Lamkin, Douglas R. Spitz, Anil K. Sood, Daniel J. Lenihan, Mian M.K. Shahzad, Eileen H. Shinn, Susan K. Lutgendorf, Koen DeGeest
Publikováno v:
Cancer. 115:1021-1027
BACKGROUND: Research suggests that glucose levels in cancer patients may be an important prognostic indicator. In ovarian tumors, increased expression of glucose transporter 1 (GLUT1), a transmembrane protein responsible for glucose uptake, is relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242dc5a52c9784eabc1780de390e2aec
https://doi.org/10.1002/cncr.24126
https://doi.org/10.1002/cncr.24126
Autor:
David M. Lubaroff, Dev Karan
Publikováno v:
Advanced Drug Delivery Reviews. 61:268-274
The use of an adenovirus transduced to express a prostate cancer antigen (PSA) as a vaccine for the treatment of prostate cancer has been shown to be active in the destruction of antigen-expressing prostate tumor cells in a pre-clinical model, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72cee5774e7df99f234c165a82044c85
https://doi.org/10.1016/j.addr.2008.12.005
https://doi.org/10.1016/j.addr.2008.12.005