Zobrazeno 1 - 10
of 65
pro vyhledávání: '"David M Gracey"'
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-5 (2023)
Abstract Background While anaemia following liver transplant is common, anaemia in the context of BK viraemia is not a commonly recognised phenomenon. Case presentation We present the case of 59-year old gentleman with severe anaemia in the context o
Externí odkaz:
https://doaj.org/article/cfa65d8501a14f5da4b3f8d049dbfc13
Autor:
Jack E Heron, Hamish McManus, Tobias Vickers, Kathleen Ryan, Edwina Wright, Allison Carter, Mark Stoove, Jason Asselin, Andrew Grulich, Basil Donovan, Rebecca Guy, Rick Varma, Marcus Chen, Nathan Ryder, David A Lewis, David J Templeton, Catherine C O'Connor, David M Gracey, ACCESS Collaboration
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0280339 (2023)
BackgroundTenofovir disoproxil fumarate (TDF) is associated with adverse renal outcomes when prescribed for HIV infection. There are few data concerning real-world renal outcomes amongst patients prescribed TDF for pre-exposure prophylaxis (PrEP).Met
Externí odkaz:
https://doaj.org/article/4521ee89fb3946b4b84878b76f901cae
Autor:
Julian Singer, Yan Jun Li, Tracey Ying, Leyla J Aouad, David M Gracey, Laurence Macia, Huiling Wu, Steven J Chadban
Publikováno v:
BMJ Open, Vol 11, Iss 4 (2021)
Introduction Kidney transplantation remains the best treatment for end-stage kidney disease, however the requirement for indefinite immunosuppression increases the risk of cardiovascular disease, cancer and infection, leading to a reduction in long-t
Externí odkaz:
https://doaj.org/article/9138e5dd23b347968e1579fcc3d13535
Autor:
Alexander Gilbert, Lindsey Robertson, Jack E Heron, Steve Chadban, Chiratidzo Ndhlovu, Rumbi F Dahwa, David M Gracey
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241229 (2020)
BackgroundAcute kidney injury (AKI) is predominantly a disease of low and middle-income countries. Despite this, there is a particular paucity of data regarding AKI in Africa. Most published studies were conducted prior to the most recent Kidney Dise
Externí odkaz:
https://doaj.org/article/7f05b6546f49486bade1ff6771ae513b
Autor:
Jack Edward Heron, Sarah M Norman, Jeannie Yoo, Kirsty Lembke, Catherine C O'Connor, Clare E Weston, David M Gracey
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223224 (2019)
BackgroundNon-AIDS-related mortality rates among HIV-infected patients still exceed those of their uninfected peers. A major driver of this excess mortality is a higher risk of non-infectious comorbidities, including cardiovascular disease, chronic k
Externí odkaz:
https://doaj.org/article/259b7e519e2f4446a9ef9dfa2c575138
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210106 (2019)
BackgroundPre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) significantly reduces the risk of HIV acquisition. TDF is a known nephrotoxin however, renal dysfunction from TDF is mostly reversible following disc
Externí odkaz:
https://doaj.org/article/e3a714d9864b47d9a07c527c12f77dad
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-6 (2020)
Abstract Background The nucleotide reverse transcriptase inhibitor Tenofovir Alafenamide (TAF) is a novel pro-drug of tenofovir (TFV) and possesses a superior renal safety profile compared with tenofovir disoproxil fumerate (TDF). Due to unique pharm
Externí odkaz:
https://doaj.org/article/1b9148ab0de64f4aa768c267e4b81f79
Publikováno v:
AIDS Research and Therapy, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Chronic kidney disease (CKD) is a comorbidity of major clinical significance amongst people living with HIV (PLWHIV) and is associated with significant morbidity and mortality. The prevalence of CKD is rising, despite the widespread use of a
Externí odkaz:
https://doaj.org/article/9f0e7a26105b491899b2e2566a375e5a
Autor:
Mitchell Hunter-Dickson, Douglas Drak, Matthew Anderson, Tinei Shamu, Cleophas Chimbetete, Rumbidzai Dahwa, David M. Gracey
Publikováno v:
BMC Nephrology. 24
Background Renal impairment in people living with HIV (PWH) in Sub-Saharan Africa is common and associated with increased morbidity and mortality. The ideal equation to estimate glomerular filtration rate (eGFR) in this population remains unclear. Th
Publikováno v:
Sexual Health. 19:224-227
Background Tenofovir disoproxil is efficacious in the preventing HIV infection as part of a pre-exposure prophylaxis (PrEP) regimen. Although its use has been associated with impaired renal function, instances of Fanconi syndrome are extremely rare.