Zobrazeno 1 - 10
of 118
pro vyhledávání: '"David M Gardiner"'
Autor:
Jeffrey Lehrberg, David M Gardiner
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123186 (2015)
We have modified and optimized the technique of organotypic slice culture in order to study the mechanisms regulating growth and pattern formation in regenerating axolotl limb blastemas. Blastema cells maintain many of the behaviors that are characte
Externí odkaz:
https://doaj.org/article/7b6a530d6b7d4dccaa1fc16fd4af0211
Autor:
Cristian Aguilar, David M Gardiner
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134791 (2015)
The formation of a blastema during regeneration of an axolotl limb involves important changes in the behavior and function of cells at the site of injury. One of the earliest events is the formation of the wound epithelium and subsequently the apical
Externí odkaz:
https://doaj.org/article/283bd84060e5484da3f176539145a769
Autor:
Catherine D McCusker, David M Gardiner
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e77064 (2013)
The regenerating region of an amputated salamander limb, known as the blastema, has the amazing capacity to replace exactly the missing structures. By grafting cells from different stages and regions of blastemas induced to form on donor animals expr
Externí odkaz:
https://doaj.org/article/a7de080a332d4864b1df406ccd8ce020
Autor:
Jangwoo Lee, David M Gardiner
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50615 (2012)
In spite of numerous investigations of regenerating salamander limbs, little attention has been paid to the details of how joints are reformed. An understanding of the process and mechanisms of joint regeneration in this model system for tetrapod lim
Externí odkaz:
https://doaj.org/article/f0cb860f6c824cdaa7012d9f77a4b4ed
Autor:
C T Laurencin, Jeffrey D. Esko, Takayoshi Otsuka, David M. Gardiner, Anne Q. Phan, S V Bryant
Publikováno v:
Regenerative engineering and translational medicine, vol 6, iss 1
Regen Eng Transl Med
Regen Eng Transl Med
Limb regeneration is the outcome of a complex sequence of events that are mediated by interactions between cells derived from the tissues of the amputated stump. Early in regeneration, these interactions are mediated by growth factor/morphogen signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98698d02aad7bed498eae4e3b0515de
https://escholarship.org/uc/item/98q0b9qr
https://escholarship.org/uc/item/98q0b9qr
Autor:
David M. Gardiner, Susan V. Bryant
Publikováno v:
The International Journal of Developmental Biology. 62:363-368
The explosive growth of information from genetics and genomics has led to an appreciation of the conservation of gene regulatory networks between organisms, and between development and regeneration. With ever increasing knowledge, it will be possible
Autor:
David M. Gardiner
Publikováno v:
Journal of morphology. 155(2)
The sperm of the shiner surfperch are packaged into high density aggregations which are introduced into the female genital tract at insemination. Germ cell differentiation occurs within cysts formed by nongerminal Sertoli cells. In late spermiogenesi
Autor:
Ken Muneoka, Alex Palumbo, Antony Athippozhy, Radha Nagarajan, David M. Gardiner, Arnold J. Stromberg, S. Randal Voss
Publikováno v:
Regeneration. 2:120-136
While it is appreciated that global gene expression analyses can provide novel insights about complex biological processes, experiments are generally insufficiently powered to achieve this goal. Here we report the results of a robust microarray exper
Publikováno v:
Regeneration. 2:54-71
The axolotl is one of the few tetrapods that are capable of regenerating complicated biological structures, such as complete limbs, throughout adulthood. Upon injury the axolotl generates a population of regeneration-competent limb progenitor cells k
Autor:
David M. Gardiner
Regenerative Engineering and Developmental Biology: Principles and Applications examines cutting-edge developments in the field of regenerative engineering. Specific attention is given to activities that embrace the importance of integrating developm