Zobrazeno 1 - 10
of 272
pro vyhledávání: '"David M Findlay"'
Autor:
Asiri R Wijenayaka, Masakazu Kogawa, Hui Peng Lim, Lynda F Bonewald, David M Findlay, Gerald J Atkins
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25900 (2011)
Sclerostin is a product of mature osteocytes embedded in mineralised bone and is a negative regulator of bone mass and osteoblast differentiation. While evidence suggests that sclerostin has an anti-anabolic role, the possibility also exists that scl
Externí odkaz:
https://doaj.org/article/3f5c6d5f83b240f389dc651901794d86
Autor:
David M. Findlay, Author
This book opens the door to the frequently obscure world of scientific discovery, not just to document discoveries, but also to explain how these discoveries come about. As an example, it tells, in an accessible way, the exciting story of the importa
Autor:
Renee T. Ormsby, Kunihiro Hosaka, Andreas Evdokiou, Andreani Odysseos, David M. Findlay, Lucian B. Solomon, Gerald J. Atkins
Publikováno v:
Prosthesis, Vol 4, Iss 3, Pp 480-489 (2022)
Polyethylene (PE) liners are a common bearing surface of orthopaedic prostheses. Wear particles of ultra-high molecular weight PE (UHMWPE) contribute to periprosthetic osteolysis, a major cause of aseptic loosening. Vitamin E is added to some PE line
Externí odkaz:
https://doaj.org/article/a791f0e73ed54daba06f3d1af38dc229
Autor:
Dzenita Muratovic, David M. Findlay, Micaela J. Quinn, Ryan D. Quarrington, Lucian B. Solomon, Gerald J. Atkins
Publikováno v:
Osteoarthritis and Cartilage.
ObjectiveIt is unclear if different factors influence osteoarthritis (OA) progression and the changes characterising OA disease in hip and knee. We investigated the difference between hip OA and knee OA at the subchondral bone tissue and cellular lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87695933f23ebc856fc46cc2f79e3cbb
https://doi.org/10.1016/j.joca.2023.05.005
https://doi.org/10.1016/j.joca.2023.05.005
Autor:
Dongqing Yang, Asiri R. Wijenayaka, Lucian B. Solomon, Stephen M. Pederson, David M. Findlay, Stephen P. Kidd, Gerald J. Atkins
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT Periprosthetic joint infection (PJI) is a potentially devastating complication of orthopedic joint replacement surgery. PJI with associated osteomyelitis is particularly problematic and difficult to cure. Whether viable osteocytes, the predo
Externí odkaz:
https://doaj.org/article/731ea34e0e134859a77e030f1b52c1b6
Autor:
Renee T Ormsby, Kunihiro Hosaka, Andreas Evdokiou, Andreani Odysseos, David M Findlay, Lucian B. Solomon, Gerald J Atkins
Publikováno v:
Prosthesis; Volume 4; Issue 3; Pages: 480-489
Polyethylene (PE) liners are a common bearing surface of orthopaedic prostheses. Wear particles of ultra-high molecular weight PE (UHMWPE) contribute to periprosthetic osteolysis, a major cause of aseptic loosening. Vitamin E is added to some PE line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d68363455caa2d28e18696147c96855
https://doi.org/10.1101/2022.04.17.488608
https://doi.org/10.1101/2022.04.17.488608
Autor:
Mohsen Dorraki, Dzenita Muratovic, Anahita Fouladzadeh, Johan W Verjans, Andrew Allison, David M Findlay, Derek Abbott
Hip osteoarthritis (HOA) is a degenerative joint disease that leads to the progressive destruction of subchondral bone and cartilage at the hip joint. Development of effective treatments for HOA remains an open problem, primarily due to the lack of k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce6843fbb5d6fe9e56a8e36d5d443f0
https://doi.org/10.1101/2022.03.28.486155
https://doi.org/10.1101/2022.03.28.486155
Autor:
Bogdan Solomon, Ryan D. Quarrington, Dzenita Muratovic, Julia S. Kuliwaba, Xu Cao, Gerald J. Atkins, David M. Findlay
ObjectiveOver-activity of transforming growth factor β1 (TGFβ1) in subchondral bone has a direct causal role in rodent models of knee osteoarthritis (OA), which can be blocked by TGFβ1 neutralisation. In this study, we investigated whether the spa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6ade1d417db1b4777e3138da2737e20
https://doi.org/10.1101/2021.09.13.459432
https://doi.org/10.1101/2021.09.13.459432
Autor:
Barbara M. Misof, Paul Roschger, Stéphane Blouin, Masakazu Kogawa, Gerald J. Atkins, Jochen G. Hofstaetter, Nobuaki Ito, Lucian B. Solomon, David M. Findlay, Andreas Evdokiou
Autosomal Dominant Osteopetrosis type II (ADOII), also known as Albers-Schönberg disease, is caused by mutation of the CLCN7 chloride channel gene and is characterized by reduced bone resorption. Here we report on an individual with the classic feat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a31a6e35026ce0710313faefe9c1bd8e
https://doi.org/10.1101/2021.07.08.21257202
https://doi.org/10.1101/2021.07.08.21257202
Autor:
Jochen G. Hofstaetter, Gerald J. Atkins, Hajime Kato, Masakazu Kogawa, Stéphane Blouin, Barbara M. Misof, Paul Roschger, Andreas Evdokiou, Dongqing Yang, Lucian B. Solomon, David M. Findlay, Nobuaki Ito
Publikováno v:
Calcified tissue international. 111(4)
Osteopetrosis is a heterogeneous group of rare hereditary diseases characterized by increased bone mass of poor quality. Autosomal-dominant osteopetrosis type II (ADOII) is most often caused by mutation of theCLCN7gene leading to impaired bone resorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d580563c88baaa565456ad24215df9
https://pubmed.ncbi.nlm.nih.gov/35618777
https://pubmed.ncbi.nlm.nih.gov/35618777