Zobrazeno 1 - 10
of 337
pro vyhledávání: '"David M Barrett"'
Autor:
David M Barrett, Daniel Martinez, Tiffany Smith, Jessica B Foster, Crystal Griffin, Jo Lynne Rokita, Allison Stern, Cameron Brimley, Komal Rathi, Maria V Lane, Samantha N Buongervino, Peter J Madsen, Alberto Delaidelli, Poul H Sorensen, Robert J Wechsler-Reya, Katalin Karikó, Phillip B Storm, Adam C Resnick, John M Maris, Kristopher R Bosse
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Pediatric brain tumors are the leading cause of cancer death in children with an urgent need for innovative therapies. Glypican 2 (GPC2) is a cell surface oncoprotein expressed in neuroblastoma for which targeted immunotherapies have been
Externí odkaz:
https://doaj.org/article/e7606fcfe47343a78a08e0f4943daef3
Autor:
Carl H June, David M Barrett, Stephan A Grupp, Rong Fan, Marcela V Maus, Zhiliang Bai, Stefan Lundh, Dongjoo Kim, Steven Woodhouse, Regina M Myers, Pablo G Camara, J Joseph Melenhorst
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Autologous T cells engineered to express a chimeric antigen receptor (CAR) specific for CD19 molecule have transformed the therapeutic landscape in patients with highly refractory leukemia and lymphoma, and the use of donor-generated allog
Externí odkaz:
https://doaj.org/article/d1c8e9cf34dd480380636e72e6720295
Autor:
Gregory M. Chen, Chia-Hui Chen, Jessica Perazzelli, Stephan A. Grupp, David M. Barrett, Kai Tan
Publikováno v:
Cancer Immunol Res
Chimeric antigen receptor (CAR) T-cell therapy targeting CD19 has been a clinical breakthrough for pediatric B-cell acute lymphoblastic leukemia (B-ALL), and loss of the CD19 target antigen on leukemic cells represents a major mechanism of relapse. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5af37a5d8feecb7269faaa62f1deb5
https://doi.org/10.1158/2326-6066.cir-22-0095
https://doi.org/10.1158/2326-6066.cir-22-0095
Autor:
Caroline Diorio, Rawan Shraim, Regina Myers, Edward M. Behrens, Scott Canna, Hamid Bassiri, Richard Aplenc, Chakkapong Burudpakdee, Fang Chen, Amanda M. DiNofia, Saar Gill, Vanessa Gonzalez, Michele P. Lambert, Allison Barz Leahy, Bruce L. Levine, Robert B. Lindell, Shannon L. Maude, J. Joseph Melenhorst, Haley Newman, Jessica Perazzelli, Alix E. Seif, Simon F. Lacey, Carl H. June, David M. Barrett, Stephan A. Grupp, David T. Teachey
Publikováno v:
Clinical Cancer Research. 28:3804-3813
Purpose: To study the biology and identify markers of severe cytokine release syndrome (CRS) and immune effector cell–associated neurotoxicity syndrome (ICANS) in children after chimeric antigen receptor T-cell (CAR T) treatment. Experimental Desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35fa230d856563f2e452186b3a0a53ac
https://doi.org/10.1158/1078-0432.ccr-22-0822
https://doi.org/10.1158/1078-0432.ccr-22-0822
Autor:
Kai Tan, David M. Barrett, Stephan A. Grupp, Jessica Perazzelli, Chia-Hui Chen, Gregory M. Chen
Legends for supplementary figures and tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfcba07b8c964552618492f80c7bbcf
https://doi.org/10.1158/2326-6066.22546341.v1
https://doi.org/10.1158/2326-6066.22546341.v1
Autor:
Kai Tan, David M. Barrett, Stephan A. Grupp, Jessica Perazzelli, Chia-Hui Chen, Gregory M. Chen
Chimeric antigen receptor (CAR) T-cell therapy targeting CD19 has been a clinical breakthrough for pediatric B-cell acute lymphoblastic leukemia (B-ALL), and loss of the CD19 target antigen on leukemic cells represents a major mechanism of relapse. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33976265d8fd9d219a140416e9619a49
https://doi.org/10.1158/2326-6066.c.6551154.v1
https://doi.org/10.1158/2326-6066.c.6551154.v1
Autor:
Kai Tan, David M. Barrett, Stephan A. Grupp, Jessica Perazzelli, Chia-Hui Chen, Gregory M. Chen
Details of SNVs and small indels detected from deep whole-exome sequencing in CD19 and selected genes associated with genomic instability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef2b05e5dec8acf7e10a733b05def5c
https://doi.org/10.1158/2326-6066.22546344
https://doi.org/10.1158/2326-6066.22546344
Autor:
Kai Tan, David M. Barrett, Stephan A. Grupp, Jessica Perazzelli, Chia-Hui Chen, Gregory M. Chen
Supplementary Figure 1-9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d27083c2ce5180abaf20f2069b87e8
https://doi.org/10.1158/2326-6066.22546350
https://doi.org/10.1158/2326-6066.22546350
Autor:
Andrei Thomas-Tikhonenko, Stephan A. Grupp, John M. Maris, Kristen W. Lynch, Yoseph Barash, Crystal Mackall, Terry Fry, Elad Jacoby, David Allman, Jan J. Melenhorst, Simon F. Lacey, Saar Gill, Alejandro Barrera, Pichai Raman, Shannon L. Maude, Ted J. Hofmann, Jessica Perazzelli, Elaine Y. Chung, Colleen T. Harrington, Nicole M. Martinez, Matthew R. Gazzara, Marco Ruella, Claudia Lanauze, Robyn Sussman, Glendon Wu, Derek Oldridge, Asen Bagashev, Kathryn L. Black, David M. Barrett, Elena Sotillo
Supplementary Table 1. DNA fragments synthesized and inserted into MSCV-CD19-IRES-DsRedFP via EcoRI/BglII or BglII/XhoI digestion, and later moved into pMX-IRES-Blast via EcoRI/XhoI cloning. Supplementary Table 2. Sets of primers used for PCR amplifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35429cb5175b3bba939b9bbf54000841
https://doi.org/10.1158/2159-8290.22531644
https://doi.org/10.1158/2159-8290.22531644
Autor:
Michael C. Milone, J. Joseph Melenhorst, Carl H. June, Stephan A. Grupp, Bruce L. Levine, Simon F. Lacey, John Leferovich, Changfeng Zhang, Felipe Bedoya, Megan M. Davis, Stefan M. Lundh, David M. Barrett, John Scholler, Prachi R. Patel, Joseph A. Fraietta, Roddy S. O'Connor, Selene Nunez-Cruz, Saba Ghassemi
The success of chimeric antigen receptor (CAR)–mediated immunotherapy in acute lymphoblastic leukemia (ALL) highlights the potential of T-cell therapies with directed cytotoxicity against specific tumor antigens. The efficacy of CAR T-cell therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9a1e3b462d8338fdedd469503667d5
https://doi.org/10.1158/2326-6066.c.6549262.v1
https://doi.org/10.1158/2326-6066.c.6549262.v1