Zobrazeno 1 - 10
of 243
pro vyhledávání: '"David M, Umbach"'
Autor:
Mikyeong Lee, Abhishek Kaul, James M. Ward, Qiyun Zhu, Marie Richards, Ziyue Wang, Antonio González, Christine G. Parks, Laura E. Beane Freeman, David M. Umbach, Alison A. Motsinger-Reif, Rob Knight, Stephanie J. London
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Background Chronic exposure to microorganisms inside homes can impact respiratory health. Few studies have used advanced sequencing methods to examine adult respiratory outcomes, especially continuous measures. We aimed to identify metagenom
Externí odkaz:
https://doaj.org/article/97747b8b6c014deea62feb192a18484e
Autor:
David M Umbach, Yuanyuan Li, Leping Li, Pallav Halani, Mihye Ahn, Deryck S C Yeung, Bradley Vaughn, Zheng Jane Fan
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Background The characteristics of and relationship between sleep apnoea and hypoventilation in patients with muscular dystrophy (MD) remain to be fully understood.Methods We analysed 104 in-laboratory sleep studies of 73 patients with MD with five co
Externí odkaz:
https://doaj.org/article/cf8f3c0f908c409fab3ffd9ee583e4a6
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Biological tissues consist of heterogenous populations of cells. Because gene expression patterns from bulk tissue samples reflect the contributions from all cells in the tissue, understanding the contribution of individual cell t
Externí odkaz:
https://doaj.org/article/4907238e8b17476ba7fe3658255f652e
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Human cancer cell line profiling and drug sensitivity studies provide valuable information about the therapeutic potential of drugs and their possible mechanisms of action. The goal of those studies is to translate the findings fr
Externí odkaz:
https://doaj.org/article/4b1de6683af848de92c5bf39c5ce389f
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Tumor purity is the percent of cancer cells present in a sample of tumor tissue. The non-cancerous cells (immune cells, fibroblasts, etc.) have an important role in tumor biology. The ability to determine tumor purity is important
Externí odkaz:
https://doaj.org/article/60e0f816266947b29a2b7ca97258148a
Autor:
Annah B. Wyss, Thanh T. Hoang, Hilde K. Vindenes, Julie D. White, Sinjini Sikdar, Marie Richards, Laura E. Beane-Freeman, Christine G. Parks, Mikyeong Lee, David M. Umbach, Stephanie J. London
Publikováno v:
Journal of Allergy and Clinical Immunology: Global. 1:248-256
Several studies conducted in Europe have suggested a protective association between early-life farming exposures and childhood eczema or atopic dermatitis; few studies have examined associations in adults.To investigate associations between early-lif
A comprehensive genomic pan-cancer classification using The Cancer Genome Atlas gene expression data
Autor:
Yuanyuan Li, Kai Kang, Juno M. Krahn, Nicole Croutwater, Kevin Lee, David M. Umbach, Leping Li
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background The Cancer Genome Atlas (TCGA) has generated comprehensive molecular profiles. We aim to identify a set of genes whose expression patterns can distinguish diverse tumor types. Those features may serve as biomarkers for tumor diagn
Externí odkaz:
https://doaj.org/article/73c69f5aaf2b419faf7154fd6d1767bf
Autor:
Kai Kang, Qian Meng, Igor Shats, David M Umbach, Melissa Li, Yuanyuan Li, Xiaoling Li, Leping Li
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 12, p e1007510 (2019)
Quantifying cell-type proportions and their corresponding gene expression profiles in tissue samples would enhance understanding of the contributions of individual cell types to the physiological states of the tissue. Current approaches that address
Externí odkaz:
https://doaj.org/article/806d7fdbe7eb493d84493b348ffbbaa9
Autor:
Quaker E. Harmon, Stacy A. Patchel, Shanshan Zhao, David M. Umbach, Tracy E. Cooper, Donna D. Baird
Publikováno v:
Obstetrics & Gynecology. 139:797-807
Investigate the association between use of depot medroxyprogesterone acetate (DMPA) (an injectable progestin-only contraceptive) and leiomyoma development.We conducted a cohort study in the Detroit, Michigan, area that involved four clinic visits at
Autor:
Gilberto Fronza, Alberto Inga, Michael A. Resnick, David M. Umbach, Debora Russo, Paola Menichini, Yari Ciribilli, Alessandra Bisio, Chiara Perfumo, Paola Monti
Supplementary Tables S1-S5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132685bec6202b86b32c5f9b560a6cc4
https://doi.org/10.1158/1541-7786.22519182
https://doi.org/10.1158/1541-7786.22519182