Zobrazeno 1 - 10
of 64
pro vyhledávání: '"David M, Roberts"'
Autor:
Stuart Middlemiss, Matthieu Blandenet, David M. Roberts, Andrew McMahon, James Grimshaw, Joshua M. Edwards, Zikai Sun, Kevin D. Whitley, Thierry Blu, Henrik Strahl, Séamus Holden
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Most rod-shaped bacteria elongate by inserting new cell wall material into the inner surface of the cell sidewall. This is performed by class A penicillin binding proteins (PBPs) and a highly conserved protein complex, the elongasome, which
Externí odkaz:
https://doaj.org/article/aa29a5c2d20c4c05b440ebadd6070e85
Autor:
David M. Roberts
Publikováno v:
MicrobiologyOpen, Vol 12, Iss 1, Pp n/a-n/a (2023)
Abstract ParABS (Soj‐Spo0J) systems were initially implicated in plasmid and chromosome segregation in bacteria. However, it is now increasingly understood that they play multiple roles in cell cycle events in Bacillus subtilis, and possibly other
Externí odkaz:
https://doaj.org/article/56d790aadfc34afc8c89186c1c856662
Autor:
Jamie N. Orr, Roy Neilson, Thomas E. Freitag, David M. Roberts, Keith G. Davies, Vivian C. Blok, Peter J. A. Cock
Publikováno v:
Frontiers in Plant Science, Vol 10 (2020)
Pasteuria spp. are endospore forming bacteria which act as natural antagonists to many of the most economically significant plant parasitic nematodes (PPNs). Highly species-specific nematode suppression may be observed in soils containing a sufficien
Externí odkaz:
https://doaj.org/article/0355ffc812a5491683549ce7401d9832
Autor:
Fernando Santos-Beneit, David M. Roberts, Stuart Cantlay, Joseph R. McCormick, Jeff Errington
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Protein FtsZ plays key roles in cell division and is essential in most bacterial species; exceptions include streptomycetes, which grow from the cell tip and form branched hyphae. Here, Santos-Beneit et al. show that branching allows FtsZ-independent
Externí odkaz:
https://doaj.org/article/6b47206cd70c444686984c3d36219400
Autor:
Heather A. Howell Wescott, David M. Roberts, Christian L. Allebach, Rachel Kokoczka, Tanya Parish
Publikováno v:
ACS Omega, Vol 2, Iss 1, Pp 41-51 (2017)
Externí odkaz:
https://doaj.org/article/4ea39d7f2b1e4ecd93465c88a608c642
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0205479 (2019)
Tuberculosis is a disease of global importance for which novel drugs are urgently required. We developed a whole-cell phenotypic screen which can be used to identify inhibitors of Mycobacterium tuberculosis growth. We used recombinant strains of viru
Externí odkaz:
https://doaj.org/article/5b33e04ec36148ad939de1b7fbcf3037
Autor:
Stuart Middlemiss, David M Roberts, James Grimshaw, Joshua M Edwards, Zikai Sun, Kevin D Whitley, Thierry Blu, Henrik Strahl, Séamus Holden
Most rod-shaped bacteria elongate by inserting new cell wall material into the inner surface of the cell sidewall. This is primarily performed by a highly conserved protein complex, the elongasome, which moves processively around the cell circumferen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e15087c3060956780c89888d3f6fd8e1
https://doi.org/10.1101/2023.05.10.540107
https://doi.org/10.1101/2023.05.10.540107
Autor:
Heather H. Wescott, Edison S. Zuniga, Anumita Bajpai, Carolina Trujillo, Sabine Ehrt, Dirk Schnappinger, David M. Roberts, Tanya Parish
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Tuberculosis is a massive global burden and Mycobacterium tuberculosis is increasingly resistant to first- and second-line drugs. There is an acute need for new anti-mycobacterial drugs with novel targets. We previously evaluated a series of 2-aminot
Externí odkaz:
https://doaj.org/article/9ed8713a1e5d489b801fda30e2c8d728
Autor:
Kristina N Schaefer, Teresa T Bonello, Shiping Zhang, Clara E Williams, David M Roberts, Daniel J McKay, Mark Peifer
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007339 (2018)
Wnt signaling provides a paradigm for cell-cell signals that regulate embryonic development and stem cell homeostasis and are inappropriately activated in cancers. The tumor suppressors APC and Axin form the core of the multiprotein destruction compl
Externí odkaz:
https://doaj.org/article/9098cfc7b0864aefb1d87fc3c7ad84fd
Autor:
David M, Roberts, Anna, Anchimiuk, Tomas G, Kloosterman, Heath, Murray, Ling Juan, Wu, Stephan, Gruber, Jeff, Errington
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(41)
SMC complexes, loaded at ParB