3D Printed Reactionware for Synthetic Electrochemistry with Hydrogen Fluoride Reagents

Autor: David M. Heard, Alastair J. J. Lennox, Sayad Doobary

Publikováno v: Heard, D M, Doobary, S & Lennox, A J J 2021, ' 3D Printed Reactionware for Synthetic Electrochemistry with Hydrogen Fluoride Reagents ', ChemElectroChem, vol. 8, no. 11, pp. 2070-2074 . https://doi.org/10.1002/celc.202100496

Electrochemical fluorination reactions of organic compounds frequently employ hydrogen fluoride reagents that are corrosive. The corrosive nature of these reagents necessitates either the construction or purchase of cells that are stable to hydrogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf7c5f3696e8bb91c0642e514504c0b
https://doi.org/10.1002/celc.202100496

ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

Autor: Charles E. Evans, Patrick G. Kehoe, Giulia Piva, Mark Andrew Good, Christine L. Willis, David M. Heard, Emma Jane Kidd, James Scott Miners

Publikováno v: Acta Neuropathol
Acta Neuropathologica
Evans, C, Miners, J S, Piva, G, Willis, C L, Heard, D M, Kidd, E J, Good, M & Kehoe, P G 2020, ' ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease ', Acta Neuropathologica, vol. 139, pp. 485–502 . https://doi.org/10.1007/s00401-019-02098-6, https://doi.org/10.1007/s00401-020-02229-4

Mid-life hypertension and cerebrovascular dysfunction are associated with increased risk of later life dementia, including Alzheimer’s disease (AD). The classical renin–angiotensin system (cRAS), a physiological regulator of blood pressure, funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dceaf9c852a7cfa3516871b1d3b29087
https://doi.org/10.1007/s00401-019-02098-6

Minimal manual input

Autor: David M. Heard, Alastair J. J. Lennox

Publikováno v: Heard, D M & Lennox, A J J 2020, ' Minimal manual input ', Nature Chemistry, vol. 12, no. 2, pp. 113-114 . https://doi.org/10.1038/s41557-019-0416-5

Synthetic organic chemistry is increasingly automated, data rich and intelligent. At the Automated Synthesis Forum, industry and academia showcased their recent progress towards this augmented future.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b81baa94270b39391ee89113bd71f99
https://research-information.bris.ac.uk/en/publications/4e7816d1-74e4-467c-a1f2-2a5ea12ec9ab

Structural and Synthetic Studies on Maleic Anhydride and Related Diacid Natural Products

Autor: Thomas J. Simpson, Emyr R. Tayler, David M. Heard, Russell J. Cox, Christine L. Willis

Publikováno v: Heard, D M, Cox, R, Simpson, T J & Willis, C L 2019, ' Structural and Synthetic Studies on Maleic Anhydride and Related Diacid Natural Products. ', Tetrahedron . https://doi.org/10.1016/j.tet.2019.130717

A concise approach has been developed for the total syntheses of tricladic acids A, B and C previously isolated from Tricladium castaneicola confirming the structures of these fungal natural products. The required (E)-1,3-diene scaffolds were generat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe63af9153e45068db794824e74eb65
https://hdl.handle.net/1983/53998d06-9017-4cfb-822b-c6453348000a