Výsledky vyhledávání - "David M, Clarke"

Hepatitis C virus in people with serious mental illness: an analysis of the care cascade at a tertiary health service with a pilot 'identify and treat' strategy

Autor: Suresh Sundram, Timothy Phan, William Sievert, Danny Con, Ian Woolley, Michael Rudi Braude, Anouk Dev, David M Clarke

Publikováno v: Internal medicine journalReferences.

BACKGROUND People with serious mental illness (SMI) are underserved from a hepatitis C Virus (HCV) screening and treatment perspective. AIMS To examine the HCV care cascade in people with SMI and to pilot a supported HCV treatment integration program

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbde2f61daeff5489c12d8ed874bdce
https://pubmed.ncbi.nlm.nih.gov/34719839

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Differences by age and sex in adolescent suicide

Autor: Stephanie Lee, David M Clarke, Eldho Paul, Robert Roseby, Jeremy Dwyer, Sophie Treleaven

Publikováno v: Australian and New Zealand Journal of Public Health, Vol 43, Iss 3, Pp 248-253 (2019)

Objectives: To compare demographic and psychosocial characteristics of completed suicide between younger and older adolescents, and by sex. Methods: Data was collected from the Victorian Suicide Register, which contains information on suicides report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494a8c0c6339e7d80f731d4366c96882
https://doaj.org/article/516b5b87642344ce8161280bdd8454bf

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MP16-07 LOSS OF SNAI2 IN PROSTATE CANCER DEFINES PATIENT RESPONSE TO ANDROGEN DEPRIVATION THERAPY

Autor: Mareck Cmero, Niall M. Corcoran, Anthony J. Costello, Patrick Mccoy, Christopher M. Hovens, David M Clarke, Paul Ruljancich, Andrew Ryan, Natalie Kurganovs, Philip Dundee, Phillip Parente

Publikováno v: Journal of Urology. 203

INTRODUCTION AND OBJECTIVE:Androgen receptor (AR) signalling is important in prostate cancer progression, and therapies that specifically target this pathway are the mainstay of treatment for advan...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ab4b6578b4ba2423eae994b02cfbbd7
https://doi.org/10.1097/ju.0000000000000841.07

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Quality of Life in Gulf War Veterans: the Influence of Recency and Persistence of Psychiatric Morbidity

Autor: Helen L Kelsall, David M Clarke, Breanna Wright, Malcolm R Sim

Publikováno v: Applied Research in Quality of Life. 14:23-38

Important contributors to quality of life (QOL), such as psychosocial factors, have received limited exploration in veteran populations, in contrast to a significant amount of research focused on health-related quality of life (HRQL). This study inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40cf4d4545c5ad56f9f0987bd9621abb
https://doi.org/10.1007/s11482-017-9579-7

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Medical student psychological distress and academic performance

Autor: Kylie Horne, Sally Ayoub, Julie Baulch, David M Clarke, Arunaz Kumar, Rebecca Pellicano, Michelle Theresa Leech, Eric F Morand, Margaret Hay, Claire Dendle, Irene Tatjana Lichtwark

Publikováno v: Medical Teacher. 40:1257-1263

The impact of medical student psychological distress on academic performance has not been systematically examined. This study provided an opportunity to closely examine the potential impacts of workplace and study related stress factors on student's

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277c5ba55438d07f2f56803d87bc5bec
https://doi.org/10.1080/0142159x.2018.1427222

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Akademický článek

Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein.

Autor: Zsolt Bikadi, Istvan Hazai, David Malik, Katalin Jemnitz, Zsuzsa Veres, Peter Hari, Zhanglin Ni, Tip W Loo, David M Clarke, Eszter Hazai, Qingcheng Mao

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e25815 (2011)

Human P-glycoprotein (P-gp) is an ATP-binding cassette multidrug transporter that confers resistance to a wide range of chemotherapeutic agents in cancer cells by active efflux of the drugs from cells. P-gp also plays a key role in limiting oral abso

Externí odkaz: https://doaj.org/article/a19f57097012451dab15ef5acf742c53

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Thiol-reactive drug substrates of human P-glycoprotein label the same sites to activate ATPase activity in membranes or dodecyl maltoside detergent micelles

Autor: David M. Clarke, Tip W. Loo

Publikováno v: Biochemical and Biophysical Research Communications. 488:573-577

P-glycoprotein (P-gp, ABCB1) is an ABC drug pump that is clinically important because it is involved in multidrug resistance. Many studies have used purified P-gp in detergent (n-dodecyl-β-D-maltoside; DM) micelles to map the locations of the drug-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259313812363b2e70e688a0ba3363d9a
https://doi.org/10.1016/j.bbrc.2017.05.106

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Refinement and revalidation of the demoralization scale: The DS-II-external validity

Autor: Michael Franco, Susan Burney, Courtney Hempton, Merlina Sulistio, Joanne Elizabeth Brooker, Natasha Michael, David W. Kissane, Sophie Robinson, David M Clarke, Mehmet Ozmen, Jane Fischer

Publikováno v: Cancer. 122:2260-2267

BACKGROUND The Demoralization Scale (DS) was initially validated in 2004 to enable the measurement of demoralization in patients with advanced cancer. Subsequent shortcomings indicated the need for psychometric strengthening. Here, the authors report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01c44e4a515a602fd6a526c15e5da99b
https://doi.org/10.1002/cncr.30012

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