Zobrazeno 1 - 10
of 232
pro vyhledávání: '"David M, Bodine"'
Autor:
Rini H Pek, Xiaojing Yuan, Nicole Rietzschel, Jianbing Zhang, Laurie Jackson, Eiji Nishibori, Ana Ribeiro, William Simmons, Jaya Jagadeesh, Hiroshi Sugimoto, Md Zahidul Alam, Lisa Garrett, Malay Haldar, Martina Ralle, John D Phillips, David M Bodine, Iqbal Hamza
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/d8c0bfb69a4940ad97e5ac2b5f0ee7a2
Autor:
Anindita Roy, Guanlin Wang, Deena Iskander, Sorcha O’Byrne, Natalina Elliott, Jennifer O’Sullivan, Gemma Buck, Elisabeth F. Heuston, Wei Xiong Wen, Alba Rodriguez Meira, Peng Hua, Anastasios Karadimitris, Adam J. Mead, David M. Bodine, Irene Roberts, Bethan Psaila, Supat Thongjuea
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109698- (2021)
Summary: Human hematopoiesis is a dynamic process that starts in utero 18–21 days post-conception. Understanding the site- and stage-specific variation in hematopoiesis is important if we are to understand the origin of hematological disorders, man
Externí odkaz:
https://doaj.org/article/9d0c2134b4a34cc79ac5a40723153498
Autor:
Cheryl A Keller, Alexander Q Wixom, Elisabeth F Heuston, Belinda Giardine, Chris C -S Hsiung, Maria R Long, Amber Miller, Stacie M Anderson, April Cockburn, Gerd A Blobel, David M Bodine, Ross C Hardison
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
AbstractChromatin immunoprecipitation followed by massively parallel, high throughput sequencing (ChIP-seq) is the method of choice for genome-wide identification of DNA segments bound by specific transcription factors or in chromatin with particular
Externí odkaz:
https://doaj.org/article/187ad77994884baf9b47056148b28010
Autor:
Elisabeth F. Heuston, Cheryl A. Keller, Jens Lichtenberg, Belinda Giardine, Stacie M. Anderson, NIH Intramural Sequencing Center, Ross C. Hardison, David M. Bodine
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-18 (2018)
Abstract Background Enhancers and promoters are cis-acting regulatory elements associated with lineage-specific gene expression. Previous studies showed that different categories of active regulatory elements are in regions of open chromatin, and eac
Externí odkaz:
https://doaj.org/article/ffa0091b021042a59e44f4d492feec23
Autor:
Rini H Pek, Xiaojing Yuan, Nicole Rietzschel, Jianbing Zhang, Laurie Jackson, Eiji Nishibori, Ana Ribeiro, William Simmons, Jaya Jagadeesh, Hiroshi Sugimoto, Md Zahidul Alam, Lisa Garrett, Malay Haldar, Martina Ralle, John D Phillips, David M Bodine, Iqbal Hamza
Publikováno v:
eLife, Vol 8 (2019)
Free heme is cytotoxic as exemplified by hemolytic diseases and genetic deficiencies in heme recycling and detoxifying pathways. Thus, intracellular accumulation of heme has not been observed in mammalian cells to date. Here we show that mice deficie
Externí odkaz:
https://doaj.org/article/4e86e16fa4d9480ca2abf87f8ab5d9ba
Autor:
Sunmi Park, Cho Rong Han, Jeong Won Park, Li Zhao, Xuguang Zhu, Mark Willingham, David M Bodine, Sheue-Yann Cheng
Publikováno v:
PLoS Genetics, Vol 13, Iss 9, p e1006991 (2017)
Patients with mutations of the THRA gene exhibit classical features of hypothyroidism, including erythroid disorders. We previously created a mutant mouse expressing a mutated TRα1 (denoted as PV; Thra1PV/+ mouse) that faithfully reproduces the clas
Externí odkaz:
https://doaj.org/article/d4f2878eafa2414cbdb331d679ab8c0d
Autor:
Rohitash Jamwal, Lily C. Wain, Christopher Copeland, Penelope A. Kosinski, Megan Wind-Rotolo, Ilya Gertsman, William Eaton, David M Bodine, Lenny Dang, Swee Lay Thein
Publikováno v:
Blood. 140:950-951
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11666083aa01499d2dd874c6531fdd82
https://doi.org/10.1182/blood-2022-156591
https://doi.org/10.1182/blood-2022-156591
Publikováno v:
Blood. 140:8247-8248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc87810c1f13714af31a29a984b21b9c
https://doi.org/10.1182/blood-2022-156579
https://doi.org/10.1182/blood-2022-156579
Autor:
Jianshi Yu, Jens Lichtenberg, John D. Phillips, Pengcheng Wang, Maureen A. Kane, Ian G. Chambers, Iqbal Hamza, David M. Bodine, Kumar P
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Multidrug Resistance Proteins (MRPs) are transporters that play critical roles in cancer even though the physiological substrates of these enigmatic transporters are poorly elucidated. InCaenorhabditis elegans, MRP5/ABCC5 is an essential heme exporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b534fdc3ab914cf79b767caf9654128
https://doi.org/10.1073/pnas.2111617119
https://doi.org/10.1073/pnas.2111617119
Autor:
C Christodoulidou, H Ren, M H Zaidi, Adam J. Mead, Anindita Roy, Alexia Katsarou, Bethan Psaila, Leena Karnik, Q Al-Oqaily, Deena Iskander, Valentina S. Caputo, Yvonne Harrington, Kanagaraju Ponnusamy, David M. Bodine, Pritesh Trivedi, Aristeidis Chaidos, Nikolaos Trasanidis, Supat Thongjuea, Mark Robinson, J de la Fuente, Marjorie Brand, Zeinab Mokhtari, Kikkeri N. Naresh, Guanlin Wang, C G Palii, Elisabeth F. Heuston, Irene Roberts, Richard Szydlo, Anastasios Karadimitris
Ribosome dysfunction underlies the pathogenesis of many cancers and heritable ribosomopathies. Here, we investigate how mutations in either ribosomal protein large (RPL) or ribosomal protein small (RPS) subunit genes selectively affect erythroid prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7beb80b780f8923efa20f1cd028371
https://ora.ox.ac.uk/objects/uuid:8537a5fd-eb59-46b0-80f7-b19bd5159ab7
https://ora.ox.ac.uk/objects/uuid:8537a5fd-eb59-46b0-80f7-b19bd5159ab7
