Zobrazeno 1 - 10
of 198
pro vyhledávání: '"David M, Bannerman"'
Autor:
Takahiro Shimizu, Stuart G. Nayar, Matthew Swire, Yi Jiang, Matthew Grist, Malte Kaller, Cassandra Sampaio Baptista, David M. Bannerman, Heidi Johansen-Berg, Katsutoshi Ogasawara, Koujiro Tohyama, Huiliang Li, William D. Richardson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Previous work has shown that motor skill learning stimulates and requires generation of myelinating oligodendrocytes (OLs) from their precursor cells (OLPs) in the brains of adult mice. In the present study we ask whether OL production is al
Externí odkaz:
https://doaj.org/article/0c5951f15afa4a27aeb235a513dc66e0
Autor:
Ahmed Eltokhi, Ilaria Bertocchi, Andrei Rozov, Vidar Jensen, Thilo Borchardt, Amy Taylor, Catia C. Proenca, John Nick P. Rawlins, David M. Bannerman, Rolf Sprengel
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108116- (2023)
Summary: Pharmacological studies established a role for AMPARs in the mammalian forebrain in spatial memory performance. Here we generated global GluA1/3 double knockout mice (Gria1/3−/−) and conditional knockouts lacking GluA1 and GluA3 AMPAR su
Externí odkaz:
https://doaj.org/article/3d19046a94f54e098f4d4195cc9ae8b8
Autor:
Christopher W. Thomas, Cristina Blanco-Duque, Benjamin J. Bréant, Guy M. Goodwin, Trevor Sharp, David M. Bannerman, Vladyslav V. Vyazovskiy
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Serotonergic psychedelic drugs, such as psilocin (4-hydroxy-N,N-dimethyltryptamine), profoundly alter the quality of consciousness through mechanisms which are incompletely understood. Growing evidence suggests that a single psychedelic expe
Externí odkaz:
https://doaj.org/article/6caaa8a3ea294d27b106c6c2d4ac8afc
Autor:
Gauri Ang, Laurence A. Brown, Shu K. E. Tam, Kay E. Davies, Russell G. Foster, Paul J. Harrison, Rolf Sprengel, Vladyslav V. Vyazovskiy, Peter L. Oliver, David M. Bannerman, Stuart N. Peirson
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Dysfunction of the glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor GluA1 subunit and deficits in synaptic plasticity are implicated in schizophrenia and sleep and circadian rhythm disruption. To investigate th
Externí odkaz:
https://doaj.org/article/db96924aa90f4475ae84a2e870b1ccac
Autor:
Linus Milinski, Simon P. Fisher, Nanyi Cui, Laura E. McKillop, Cristina Blanco-Duque, Gauri Ang, Tomoko Yamagata, David M. Bannerman, Vladyslav V. Vyazovskiy
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Homeostatic regulation of sleep is reflected in the maintenance of a daily balance between sleep and wakefulness. Although numerous internal and external factors can influence sleep, it is unclear whether and to what extent the pr
Externí odkaz:
https://doaj.org/article/dc6a612dba99435da68acfbd495fabb2
Autor:
Ilaria Bertocchi, Ahmed Eltokhi, Andrey Rozov, Vivan Nguyễn Chi, Vidar Jensen, Thorsten Bus, Verena Pawlak, Marta Serafino, Hannah Sonntag, Boyi Yang, Nail Burnashev, Shi-Bin Li, Horst A. Obenhaus, Martin Both, Burkhard Niewoehner, Frank N. Single, Michael Briese, Thomas Boerner, Peter Gass, John Nick P. Rawlins, Georg Köhr, David M. Bannerman, Rolf Sprengel
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-21 (2021)
Ilaria Bertocchi et al. use a mouse model of Grin2a dysfunction to show that activity-independent NMDA receptors are involved in audiogenic seizure generation. Their results suggest a role for NMDA receptors in maintaining an appropriate response to
Externí odkaz:
https://doaj.org/article/2aca38124f6b4bf6abea581f18e3486f
Autor:
Sonia O. Spitzer, Andrzej Tkacz, Helene M. Savignac, Matthew Cooper, Natasa Giallourou, Edward O. Mann, David M. Bannerman, Jonathan R. Swann, Daniel C. Anthony, Philip S. Poole, Philip W.J. Burnet
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103113- (2021)
Summary: We have shown previously that prebiotic (Bimuno galacto-oligosacharides, B-GOS®) administration to neonatal rats increased hippocampal NMDAR proteins. The present study has investigated the effects of postnatal B-GOS® supplementation on hi
Externí odkaz:
https://doaj.org/article/f49c809af1034cb7bc3ed433aa006d4b
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The development of current neuroleptics was largely aiming to decrease excessive dopaminergic signaling in the striatum. However, the notion that abnormal dopamine creates psychotic symptoms by causing an aberrant assignment of salience that drives m
Externí odkaz:
https://doaj.org/article/9ef3ed9449964a9d809ff79da2fab625
Autor:
David M. Bannerman, Rolf Sprengel, Mark E. Walton, Thomas Jahans-Price, Gary Gilmour, Paul Harrison, Thomas Boerner, Anna Huber, Marios C Panayi, David J. Sanderson
Publikováno v:
Molecular Psychiatry, 2022, Vol.28(2023), pp.579-587 [Peer Reviewed Journal]
Psychosis in disorders like schizophrenia is commonly associated with aberrant salience and elevated striatal dopamine. However, the underlying cause(s) of this hyper-dopaminergic state remain elusive. Various lines of evidence point to glutamatergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ec5d968a8f2b0bdf5c365242fcaa44
https://doi.org/10.1038/s41380-022-01861-8
https://doi.org/10.1038/s41380-022-01861-8
Autor:
David J. Sanderson, Aletheia Lee, Rolf Sprengel, Peter H. Seeburg, Paul J. Harrison, David M. Bannerman
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The GluA1 AMPAR subunit (encoded by the Gria1 gene) has been implicated in schizophrenia. Gria1 knockout in mice results in recently experienced stimuli acquiring aberrantly high salience. This suggests that GluA1 may be important for learni
Externí odkaz:
https://doaj.org/article/b9ce5fc089bb499b97f2ec2b7df45736