Zobrazeno 1 - 10
of 19
pro vyhledávání: '"David Lukacsovich"'
Autor:
Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma, X. Steven Chen, Brian Kunkle, Eden R. Martin, Lily Wang
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTDNA methylation (DNAm) plays a crucial role in a number of complex diseases. However, the reliability of DNAm levels measured using Illumina arrays varies across different probes. Previous research primarily assessed probe reliability by comp
Externí odkaz:
https://doaj.org/article/4ce06caaeaea44738879447256113558
Autor:
Sara Pierre-Ferrer, Ben Collins, David Lukacsovich, Shao’Ang Wen, Yuchen Cai, Jochen Winterer, Jun Yan, Lene Pedersen, Csaba Földy, Steven A. Brown
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114220- (2024)
Summary: The suprachiasmatic nucleus (SCN) encodes time of day through changes in daily firing; however, the molecular mechanisms by which the SCN times behavior are not fully understood. To identify factors that could encode day/night differences in
Externí odkaz:
https://doaj.org/article/576ac02ce84442c3ba83dada9a5e989f
Autor:
Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Growing evidence has demonstrated that DNA methylation (DNAm) plays an important role in Alzheimer’s disease (AD) and that DNAm differences can be detected in the blood of AD subjects. Most studies have correlated blood DNAm wit
Externí odkaz:
https://doaj.org/article/ae8faa0469a948dca7ff5ab04c03229a
Autor:
Gyöngyi Cinege, Lilla B. Magyar, Attila L. Kovács, Zita Lerner, Gábor Juhász, David Lukacsovich, Jochen Winterer, Tamás Lukacsovich, Zoltán Hegedűs, Éva Kurucz, Dan Hultmark, Csaba Földy, István Andó
Publikováno v:
Journal of Innate Immunity, Pp 1-20 (2021)
Multinucleated giant hemocytes (MGHs) represent a novel type of blood cell in insects that participate in a highly efficient immune response against parasitoid wasps involving isolation and killing of the parasite. Previously, we showed that circulat
Externí odkaz:
https://doaj.org/article/de772a7c3fba4482b02f904924d5e6b0
Autor:
Wenshu Luo, Natalia Andrea Cruz-Ochoa, Charlotte Seng, Matteo Egger, David Lukacsovich, Tamás Lukacsovich, Csaba Földy
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Circuit formation is a defining characteristic of the developing brain. However, multiple lines of evidence suggest that circuit formation can also take place in adults, the mechanisms of which remain poorly understood. Here, we investigated the epil
Externí odkaz:
https://doaj.org/article/c2e460dc0c9b45b1a9093dc37fa8ae1d
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The relationship between gene expression and morphology to classify PV interneurons is unclear. Here, the authors show transcriptional continuity of morphologically distinct mouse hippocampal PV interneurons subtypes, combining single-cell RNA sequen
Externí odkaz:
https://doaj.org/article/30fe6870647e4bc89e435480fcc57e66
Autor:
Viktor János Oláh, David Lukacsovich, Jochen Winterer, Antónia Arszovszki, Andrea Lőrincz, Zoltan Nusser, Csaba Földy, János Szabadics
Publikováno v:
eLife, Vol 9 (2020)
CCK-expressing interneurons (CCK+INs) are crucial for controlling hippocampal activity. We found two firing phenotypes of CCK+INs in rat hippocampal CA3 area; either possessing a previously undetected membrane potential-dependent firing or regular fi
Externí odkaz:
https://doaj.org/article/3ea6275c4bc84b01a000153a8dc60387
Publikováno v:
Cell Reports, Vol 27, Iss 13, Pp 3752-3759.e4 (2019)
Summary: Neurexins are key synaptic organizers that are expressed in thousands of alternatively spliced isoforms. Because transsynaptic neurexin interactions with different postsynaptic molecules are largely isoform dependent, a cell type-level censu
Externí odkaz:
https://doaj.org/article/3600ed6719304053bfd472b021dc59cc
Cortical GABAergic interneurons have been shown to fulfil important roles by inhibiting excitatory principal neurons. Recent transcriptomic studies have confirmed seminal discoveries that used anatomic and electrophysiological methods highlighting th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4847ee0bf1c06d5667a224bd3954c977
Autor:
Szilárd Szőcs, Tamas Lukacsovich, Natalia Andrea Cruz-Ochoa, Jochen Winterer, David P. Wolfer, Csaba Földy, Matteo Egger, David Lukacsovich, Andor Domonkos, Lin Que, Wenshu Luo, János Szabadics, Irmgard Amrein, Charlotte Seng, Antónia Arszovszki, Eszter Sipos, Csaba Varga
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 118 (40)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Circuit formation in the central nervous system has been historically studied during development, after which cell-autonomous and nonautonomous wiring factors inactivate. In principle, balanced reactivation of such factors could enable further wiring